암 환자의 한약-양약 상호작용에 대한 고찰
Study about Herb-Drug Interaction for Cancer Patients
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives : We present some opinions to reduce the risk of herb-drug interactions through scanning “About Herbs” of the Memorial Sloan Kettering Cancer Center Website. Methods : We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions. Results : There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.; 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-Huang Chi have positive interactions to increase the effects of the chemoagent. Conclusions : We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs.
Abstract
Objectives : We present some opinions to reduce the risk of herb-drug interactions through scanning “About Herbs” of the Memorial Sloan Kettering Cancer Center Website. Methods : We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions. Results : There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.; 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-Huang Chi have positive interactions to increase the effects of the chemoagent. Conclusions : We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs.
참고문헌 (44)
- Mary Ann Richardson, "Biopharmacologic and Herbal Therapies for Cancer", J. Nutr, 131(11S), pp.3037~3040 (2001)
- Cassileth BR, "Complementary and alternative therapies for cancer", Oncologist, 9(1), pp.80~89 (2004)
- Ni H, "Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey", Med Care, 40(4), pp.353~358 (2002)
- Meijerman I, "Herb-drug interactions in oncology: focus on mechanisms of induction", Oncologist, 11(7), pp.742~752 (2006)
- "Information resource: About herbs, botanicals and other products"[URL]
- Cassileth Lucarelli, "Herb-Drug Interactions in Oncology", pp.1~480 (2003), BC decker Inc.
- 전국한의과대학 본초학교수, "본초학", pp.1~682 (2000), 영림사
- 전국한의과대학 방제학교수, "방제학", pp.143~ (1999), 영림사
- Herr SM, "Herb-Drug Interaction handbook" (2002), Church Street Books
- Taussig SJ, "Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application", J Ethnopharmacol, 22(2), pp.191~202 (1988)
- Ju YH, "Dietary genistein negates the inhibitory effects of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice", Can Res, 62(9), pp.2474~2477 (2002)
- Upton, R., "Astragalus root: analytical, quality control and therapeutic monograph", American Herbal Pharmacopoeia, 1, pp.1~25 (1999)
- Chu DT, "Fractionated extract of Astragalus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2", J Clin Lab Immunol, 26(4), pp.183~187 (1988)
- Chu DT, "Immunotherapy with Chinese medicinal herbs. II. Reversal of Cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo", J Clin Lab Immunol, 25(3), pp.125~129 (1988)
- Somasundaram S., "Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer", Cancer Res, 62(13), pp.3868~3875 (2002)
- Ju YH, "Dietary genistein negates the inhibitory effects of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice", Can Res, 62(2), pp.2474~2477 (2002)
- Liu B, "Low-dose dietary phytoestrogen abrogates tamoxifen-associated mammary tumor prevention", Cancer Res, 65(3), pp.879~886 (2005)
- Mathijssen RHJ, "Effects of St. Johns wort on irinotecan metabolism", J Natl Cancer Inst, 94(16), pp.1247~1249 (2002)
- Smith P, "The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylate", Pharmacotherapy, 24(11), pp.1508~1514 (2004)
- Frye RF, "Effect of St. John's wort on imatinib mesylate pharmacokinetics", Clin Pharmacol Ther, 76(4), pp.323~329 (2004)
- Rubio IT, "Effect of glutamine on methotrexate efficacy and toxicity", Ann Surg, 227(5), pp.772~780 (1998)
- Mason P., "Dietary Supplements" (2001), Pharmaceutical Press
- Barrie R., "Cassileth, gary Deng. Complemwntary and Alternativw Therapies for Cancer", The Oncologist, 9(1), pp.80~89 (2004)
- Weiger WA, "Advising patients who seek complementary and alternative medical therapies for cancer", Ann Intern Med, 137(11), pp.889~903 (2002)
- Chrystal K, "The use of complementary", alternative medicine by cancer patients in a New Zealand regional cancer treatment centre, 2003, pp.116(1168), U296~
- Eisenberg DM, "Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey", JAMA, 280(18), pp.1569~1575 (1998)
- "Publication BFHC0462"[URL]
- Ernst E, "The prevalence of complementary", alternative medicine in cancer: a systematic review, 1998, pp.83, 777~782
- Pierce JP, "A randomized trial of the effect of a plant-based dietary pattern on additional breast cancer events and survival: the Women’s Healthy Eating and Living (WHEL) Study", Control Clin Trials, 23(6), pp.728~756 (2002)
- De Smet PA, "Clinical risk management of herb-drug interactions", Br J Clin Pharmacol, 63(3), pp.258~267 (2007)
- AdrianeFugh-Berman, E. Ernst, "Herb-Drug interactions: Review and assessment of report reliability", 2001 Blackwell Science Ltd Br J Clin Pharmacol, 52, pp.587~595 (2001)
- [URL]
- "Complementary/integrative medicine"[URL]
- "National Center for Complementary and Alternative Medicine"[URL]
- "Office of Cancer Complementary and Alternative Medicine"[URL]
- "Making treatment decisions: complementary and alternative therapies"[URL]
- "Complementary and alternative medicine"[URL]
- Ni H, "Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey", Med Care, 40(4), pp.353~358 (2002)
- 김정선, "Natural Standard Methodology를 이용한 암 보완대체의학의 근거 및 권고수준에 대한 연구", 대한한방내과학회지, 29(1), pp.160~176 (2008), 대한한방내과학회
- Meijerman I, "Herb-drug interactions in oncology: focus on mechanisms of induction", Oncologist, 11(7), pp.742~ (2006)
- Meijerman I, "Herb -drug interactions in oncology: focus on mechanisms of induction", Oncologist, 11(7), pp.742~752 (2006)
- 박재갑, "종양학", pp.140~174 (2003), 일조각
- Izzo AA, "Interactions between herbal medicines and prescribed drugs: a systematic review", Drugs, 61, pp.2163~2175 (2001)
- Fugh-Berman A., "Herb-drug interactions", Lancet, 355, pp.134~138 (2000)
