Microglia and Autism Spectrum Disorder: Overview of Current Evidence and Novel Immunomodulatory Treatment Options

키워드

참고문헌 (65)

1. Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators, "Prevalence of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2010", MMWR Surveill Summ, 63, pp.1~21 (2014)
2. Kim YS, "Prevalence of autism spectrum disorders in a total population sample", Am J Psychiatry, 168, pp.904~912 (2011)[DOI]
3. King MD, "Socioeconomic status and the increased prevalence of autism in California", Am Sociol Rev, 76, pp.320~346 (2011)[DOI]
4. King M, "Diagnostic change and the increased prevalence of autism", Int J Epidemiol, 38, pp.1224~1234 (2009)[DOI]
5. Kinney DK, "Autism prevalence following prenatal exposure to hurricanes and tropical storms in Louisiana", J Autism Dev Disord, 38, pp.481~488 (2008)[DOI]
6. Currenti SA, "Understanding and determining the etiology of autism", Cell Mol Neurobiol, 30, pp.161~171 (2010)[DOI]
7. Anderson GM, "Autism biomarkers: challenges, pitfalls and possibilities", J Autism Dev Disord, 45, pp.1103~1113 (2015)[DOI]
8. Solek CM, "Maternal immune activation in neurodevelopmental disorders", Dev Dyn, 247, pp.588~619 (2018)[DOI]
9. Nardone S, "The interaction between the immune system and epigenetics in the etiology of autism spectrum disorders", Front Neurosci, 10, pp.329~ (2016)
10. Bertolino B, "Beneficial effects of co-ultramicronized palmitoylethanolamide", luteolin in a mouse model of autism and in a case report of autism, 2017, pp.23, 87~98
11. Kumar H, "Minocycline ameliorates prenatal valproic acid induced autistic behaviour, biochemistry and blood brain barrier impairments in rats", Brain Res, 1630, pp.83~97 (2016)[DOI]
12. Naviaux JC, "Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy", Transl Psychiatry, 4, pp.e400~ (2014)[DOI]
13. Bauman MD, "Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring", Biol Psychiatry, 75, pp.332~341 (2014)[DOI]
14. Machado CJ, "Maternal immune activation in nonhuman primates alters social attention in juvenile offspring", Biol Psychiatry, 77, pp.823~832 (2015)[DOI]
15. Smith SE, "Maternal immune activation alters fetal brain development through interleukin-6", J Neurosci, 27, pp.10695~10702 (2007)[DOI]
16. Lin D, "Porphyromonas gingivalis infection during pregnancy increases maternal tumor necrosis factor alpha, suppresses maternal interleukin-10, and enhances fetal growth restriction and resorption in mice", Infect Immun, 71, pp.5156~5162 (2003)[DOI]
17. Golan H, "Involvement of tumor necrosis factor alpha in hippocampal development and function", Cereb Cortex, 14, pp.97~105 (2004)[DOI]
18. Gilmore JH, "Prenatal infection and risk for schizophrenia: IL-1beta, IL-6, and TNFalpha inhibit cortical neuron dendrite development", Neuropsychopharmacology, 29, pp.1221~1229 (2004)[DOI]
19. Patterson PH, "Immune involvement in schizophrenia and autism: etiology, pathology and animal models", Behav Brain Res, 204, pp.313~321 (2009)[DOI]
20. Li X, "Elevated immune response in the brain of autistic patients", J Neuroimmunol, 207, pp.111~116 (2009)[DOI]
21. Vargas DL, "Neuroglial activation and neuroinflammation in the brain of patients with autism", Ann Neurol, 57, pp.67~81 (2005)[DOI]
22. Casano AM, "Microglia: multitasking specialists of the brain", Dev Cell, 32, pp.469~477 (2015)[DOI]
23. Ginhoux F, "Fate mapping analysis reveals that adult microglia derive from primitive macrophages", Science, 330, pp.841~845 (2010)[DOI]
24. Harry GJ, "Microglia during development and aging", Pharmacol Ther, 139, pp.313~326 (2013)[DOI]
25. Schafer DP, "Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner", Neuron, 74, pp.691~705 (2012)[DOI]
26. Williamson LL, "Microglia and memory: modulation by early-life infection", J Neurosci, 31, pp.15511~15521 (2011)[DOI]
27. Tang G, "Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits", Neuron, 83, pp.1131~1143 (2014)[DOI]
28. Takano T, "Role of microglia in autism: recent advances", Dev Neurosci, 37, pp.195~202 (2015)[DOI]
29. Dirscherl K, "Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype", J Neuroinflammation, 7, pp.3~ (2010)[DOI]
30. Chen HQ, "Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation", Neurosci Lett, 448, pp.175~179 (2008)[DOI]
31. Kimata M, "Effects of luteolin, quercetin and baicalein on immunoglobulin e-mediated mediator release from human cultured mast cells", Clin Exp Allergy, 30, pp.501~508 (2000)[DOI]
32. Harwood M, "A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic", carcinogenic properties, 2007, pp.45, 2179~2205
33. Parker-Athill E, "Flavonoids, a prenatal prophylaxis via targeting JAK2", STAT3 signaling to oppose IL-6, J Neuroimmunol, pp.2009, 217[DOI]
34. Theoharides TC, "A case series of a luteolin formulation (NeuroProtek(R)) in children with autism spectrum disorders", Int J Immunopathol Pharmacol, 25, pp.317~323 (2012)[DOI]
35. Taliou A, "An open-label pilot study of a formulation containing the anti-inflammatory flavonoid luteolin and its effects on behavior in children with autism spectrum disorders", Clin Ther, 35, pp.592~602 (2013)[DOI]
36. Yong VW, "The promise of minocycline in neurology", Lancet Neurol, 3, pp.744~751 (2004)[DOI]
37. Regen F, "Inhibition of brain retinoic acid catabolism: a mechanism for minocycline's pleiotropic actions?", World J Biol Psychiatry, 17, pp.634~640 (2016)
38. Siller SS, "Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome", Neural Plast, 2012, pp.124548~ (2012)
39. Zhu F, "Minocycline and risperidone prevent microglia activation and rescue behavioral deficits induced by neonatal intrahippocampal injection of lipopolysaccharide in rats", PLoS One, 9, pp.e93966~ (2014)[DOI]
40. Kumar A, "Potential role of licofelone, minocycline and their combination against chronic fatigue stress induced behavioral, biochemical and mitochondrial alterations in mice", Pharmacol Rep, 64, pp.1105~1115 (2012)[DOI]
41. Shigemori T, "Altered microglia in the amygdala are involved in anxiety-related behaviors of a copy number variation mouse model of autism", J Nippon Med Sch, 82, pp.92~99 (2015)[DOI]
42. Paribello C, "Open-label add-on treatment trial of minocycline in fragile X syndrome", BMC Neurol, 10, pp.91~ (2010)[DOI]
43. Pardo CA, "A pilot open-label trial of minocycline in patients with autism and regressive features", J Neurodev Disord, 5, pp.9~ (2013)[DOI]
44. Ghaleiha A, "Minocycline as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind placebo-controlled trial", J Child Adolesc Psychopharmacol, 26, pp.784~791 (2016)[DOI]
45. Light AR, "Purinergic receptors activating rapid intracellular Ca increases in microglia", Neuron Glia Biol, 2, pp.125~138 (2006)
46. Naviaux RK, "Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model", PLoS One, 8, pp.e57380~ (2013)[DOI]
47. Naviaux JC, "Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model", Mol Autism, 6, pp.1~ (2015)[DOI]
48. Naviaux RK, "Low-dose suramin in autism spectrum disorder: a small, phase I", II, randomized clinical trial, 2017, pp.4, 491~505
49. Wu Y, "Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection", J Pain, 5, pp.48~55 (2004)[DOI]
50. Macova L, "Vitamin D, neurosteroids and autism", Physiol Res, 66(Supplementum 3), pp.S333~S340 (2017)
51. Dulla YA, "Regulatory mechanisms of vitamin D3 on production of nitric oxide and pro-inflammatory cytokines in microglial BV-2 cells", Neurochem Res, 41, pp.2848~2858 (2016)[DOI]
52. Boontanrart M, "Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism", J Neuroimmunol, 292, pp.126~136 (2016)[DOI]
53. Saad K, "Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder", J Child Psychol Psychiatry, 59, pp.20~29 (2018)[DOI]
54. Kerley CP, "Lack of effect of vitamin D3 supplementation in autism: a 20-week, placebo-controlled RCT", Arch Dis Child, 102, pp.1030~1036 (2017)[DOI]
55. Hatice Altun, "The Levels of Vitamin D, Vitamin D Receptor, Homocysteine and Complex B Vitamin in Children with Autism Spectrum Disorders", Clinical Psychopharmacology and Neuroscience, 16(4), pp.383~390 (2018), 대한정신약물학회[DOI]
56. Buie T, "Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report", Pediatrics, 125(Suppl 1), pp.S1~S18 (2010)[DOI]
57. Adams JB, "Gastrointestinal flora and gastrointestinal status in children with autism: comparisons to typical children and correlation with autism severity", BMC Gastroenterol, 11, pp.22~ (2011)[DOI]
58. Parracho HM, "Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children", J Med Microbiol, 54, pp.987~991 (2005)[DOI]
59. Cryan JF, "Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour", Nat Rev Neurosci, 13, pp.701~712 (2012)[DOI]
60. Tillisch K, "Consumption of fermented milk product with probiotic modulates brain activity", Gastroenterology, 144, pp.1394~1401 (2013)[DOI]
61. Alan C. Logan, "The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases", Clinical Psychopharmacology and Neuroscience, 14(2), pp.131~147 (2016), 대한정신약물학회
62. Hsiao EY, "Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders", Cell, 155, pp.1451~1463 (2013)[DOI]
63. Vuong HE, "Emerging roles for the gut microbiome in autism spectrum disorder", Biol Psychiatry, 81, pp.411~423 (2017)[DOI]
64. Kim S, "Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring", Nature, 549, pp.528~532 (2017)[DOI]
65. Erny D, "Host microbiota constantly control maturation and function of microglia in the CNS", Nat Neurosci, 18, pp.965~977 (2015)[DOI]

관련 논문AI추천