구강자극요법이 미숙아의 경구수유 이행에 미치는 효과에 대한 체계적 문헌고찰과 메타분석
A Systematic Review and Meta-Analysis on the Effects of Oral Stimulation Interventions on the Transition from Tube to Oral Feeding in Premature Infants
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목적: 이 연구의 목적은 체계적 고찰과 메타분석을 통하여 구강자극요법이 미숙아의 경구수유 이행에 미치는 효과를 확인하는 것이다. 방법: 국내․외의 데이터베이스를 이용하여 찾은 1980년부터 2015년 사이에 출판된 무작위대조군 실험연구 중 5개의 무작위대조군 연구가 선택되었다. 연구의 질은 SIGN 평가도구로 확인하였으며 메타분석은 Cochrane Review Manager software Version 5.3(RevMan)로 수행되었다. 결과 : 미숙아에게 구강자극요법을 시행하는 것은 경구수유 이행에 걸리는 시간을 단축시켰다( PMA:월경 후 연령, DOL:생 후 일수 ) 특히 이행에 필요한 생후 일수에서는 유의한 중간 효과크기를 보였다(ES=-4.95, p=.02). 또한 구강자극 요법은 입원기간에 있어 유의한 큰 효과크기(ES=-8.33, p<.001)를 보이는 것으로 확인되었다. 결론: 이러한 결과에 근거하여 구강자극요법은 미숙아의 경구수유 이행과 입원기간을 단축시키기 효과가 있었다.
Abstract
Purpose: The purpose of this study was to evaluate the effects of oral stimulation interventions on the transition from tube to oral feeding in preterm infants through systematic review. Methods: The randomized clinical trials published between 1980 and 2015 were searched using domestic and international databases, and five randomized studies were selected for this study. The quality of study was assessed by assessment tool from the SIGN and meta-analysis was performed using the Cochrane Review Manager software Version 5.3 (RevMan).Results: Oral stimulation intervention in preterm infants decreased the transition time from tube to oral feeding(Post Menstrual Age, Day of life). Especially, a significant medium effect size was found in the number of days needed on the transition (ES=-4.95, p=.02). The oral stimulation intervention also had a significant large effect on the length of stay at hospital (ES=-8.33, p<.001). Conclusion: Based on the findings, oral stimulation interventions could be useful to facilitate the transition from tube to oral feeding in preterm infants in terms of reducing the length of stay at hospital and the number of days needed on transition.
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