폐쇄성 수면무호흡증과 삶의 질 : 예비연구

Abstract

Background : While obstructive sleep apnea syndrome (OSAS) is defined by both polysomnographic abnormalities and clinical symptoms, severity is quantified primarily by the apnea-hypopnea index alone. Clinically, we have noted discordance between the severity indicated by polysomnography results and the degree of symptoms reported by some patients with OSAS. The aim of this study was to assess the quality of life (QOL) in patients with OSAS, and the relationship between the QOL, and self-reported measures and polysomnographic measures. Methods: We reviewed the clinical data and night polysomnography results in 64 patients with OSAS at our sleep disorder clinic. QOL was assessed with the Medical Outcome Study 36-Item Short-Form Health Survey (SF-36). Demographic data were obtained via structured interview and medical record review. Self-reported measures included Epworth Sleepiness Scale, Pittsburgh Sleep Quality index, Insomnia Severity Index, Berlin Questionnaire, Beck Depression Inventory, and SF-36. All subjects underwent full overnight in laboratory polysomnography for the diagnosis of OSAS. The associations between each domain on the SF-36, and self-reported measures or polysomnographic measures were examined by Spearman correlation coefficients, and regression analysis. Results : The parameters of SF-36 of the patients with OSAS correlated well with self-reported measures. The parameters of polysomnographic measures of patients with OSAS did not show correlation with that of SF-36. Conclusions : The parameters measured by polysomnography may not reflect the severity of patients with OSAS and sleep apnea disease burden should be quantified with both physiologic and subjective measures.