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혈청종양 표지자 CA 125가 극도로 상승한 경계성 난소종양 1예

Extremely elevated serum CA 125 in a borderline tumor of the ovary: A case report

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초록

경계성 상피성 난소종양은 빈도상 악성종양의 약 10% 정도를 차지한다. 경계성 난소종양은 악성종양과 비교하여 예후가 좋은데 이는 상대적으로 조기에 발견되고 특성상 조직 실질내로 침윤이 없어 보존적인 방법으로도 치유가 가능하기 때문이다. 수술 전 경계성 난소종양과 조기 악성종양을 감별진단하는 것은 중요한데 수술방법에 영향을 미치기 때문이다. 혈청종양 표지자 CA 125는 악성 난소종양의 유용한 진단적 도구이나 경계성 난소종양에서 그 임상적 의미는 아직 확실하지 않다. 저자 등은 경계성 난소종양에서 CA 125 치가 극도로 상승한 예를 수술하고 경과를 관찰하였기에 이를 간단한 문헌고찰과 함께 보고하는 바이다.

Abstract

Tumors of low malignant potential (also called borderline tumors) account for approximately 10% of malignant ovarian neoplasm. Borderline tumors have a much better prognosis and, because they are noninvasive, may be treated less radically than invasive ovarian cancer. The ability to distinguish borderline tumor from early stage malignant disease preoperatively considerably influences surgical treatment, and allows improved counseling of patients. CA 125 is a useful tumor marker in the diagnosis of malignant ovarian tumors. However, in the case of borderline ovarian tumor, the value of CA 125 as a diagnostic tool seems to be invalid. Herein, we report a case of borderline ovarian tumor with extremely elevated serum CA 125 level.

참고문헌 (20)

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