A Systematic Review and Meta-Analysis of Randomized Controlled Trials on Acupuncture for Improving Post-Operative Cognitive Dysfunction (POCD) and Chemotherapy-Related Cognitive Impairment (CRCI)
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Objectives: This study was conducted to evaluate the efficacy of Korean Medicine Therapy (KMT) for the treatment of Chemotherapy-induced Cognitive Impairment (CICI) through systematic review and meta-analysis of randomized controlled trials (RCTs) as proceeding research to further research the efficacy of KMT for CICI patients. Methods: We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines (PRISMA). The RCTs on the efficacy of KMT for treatment of CICI were searched by structured search strategies in MEDLINE, EMBASE, Cochrane library, CAJD, KISS, NDSL, KoreaMed, and OASIS. The searched RCTs were screened by inclusion and exclusion criteria. We evaluated the quality of the method in the included studies using the Jadad score and Cochran ROB tool. The efficacy outcomes were the Visual Analogue Scale (VAS) and the Clinical total Effective Rate (CER) of CICI. They were analyzed using mean difference for continuous variable or Relative Risk (RR) for Dichotomous variable in the random-effect model. The RevMan 5.3 program was used for meta-analysis. Results: We included 19 RCTs, including 653 participants, in the systematic review and meta-analysis. There were favorable results for the KMT group after the intervention compared with the pharmacotherapy group, physiotherapy group, and combined treatment group. KMT group showed improvement using CER and VAS compared with exercises, but their heterogeneities were slightly significant. KMT was more effective compared to the Rehabilitation program in CER and the subgroup analysis results showed that KMT had a significant difference compared to other therapies in VAS, to Medication therapy in CER. Conclusions: KMT presented reasonable evidence on improving the Clinical total Effective Rate and Visual Analogue Scale in CICI patients. However, further evaluation in future research is required.
Abstract
Objectives: This study was conducted to evaluate the efficacy of Korean Medicine Therapy (KMT) for the treatment of Chemotherapy-induced Cognitive Impairment (CICI) through systematic review and meta-analysis of randomized controlled trials (RCTs) as proceeding research to further research the efficacy of KMT for CICI patients. Methods: We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines (PRISMA). The RCTs on the efficacy of KMT for treatment of CICI were searched by structured search strategies in MEDLINE, EMBASE, Cochrane library, CAJD, KISS, NDSL, KoreaMed, and OASIS. The searched RCTs were screened by inclusion and exclusion criteria. We evaluated the quality of the method in the included studies using the Jadad score and Cochran ROB tool. The efficacy outcomes were the Visual Analogue Scale (VAS) and the Clinical total Effective Rate (CER) of CICI. They were analyzed using mean difference for continuous variable or Relative Risk (RR) for Dichotomous variable in the random-effect model. The RevMan 5.3 program was used for meta-analysis. Results: We included 19 RCTs, including 653 participants, in the systematic review and meta-analysis. There were favorable results for the KMT group after the intervention compared with the pharmacotherapy group, physiotherapy group, and combined treatment group. KMT group showed improvement using CER and VAS compared with exercises, but their heterogeneities were slightly significant. KMT was more effective compared to the Rehabilitation program in CER and the subgroup analysis results showed that KMT had a significant difference compared to other therapies in VAS, to Medication therapy in CER. Conclusions: KMT presented reasonable evidence on improving the Clinical total Effective Rate and Visual Analogue Scale in CICI patients. However, further evaluation in future research is required.
참고문헌 (56)
- Coleman MP, "Cancer survival in Australia, Canada, Denmark, Norway, Sweden and the UK, 1995-2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data", The Lancet, 377(9760), pp.127~138 (2011)
- 김경혜, "항암화학요법을 받은 유방암 환자의 인지기능", Asian Oncology Nursing, 12(1), pp.1~11 (2012), 대한종양간호학회
- Hess LM, "Chemotherapy-related change in cognitive function: a conceptual model", Oncology Nursing Forum, 34, pp.981~994 (2007)
- Denlinger CS, "Survivorship: cognitive function, version 1.2014", Journal of the National Comprehensive Cancer Network, 12(7), pp.976~986 (2014)
- Ballard C, "Optimised anaesthesia to reduce post operative cognitive decline(POCD)in older patients undergoing elective surgery, a randomised controlled trial", PLoS One, 7(6), pp.e37410~ (2012)
- Nascimento CM, "Physical exercise improves peripheral BDNF levels and cognitive functions in mild cognitive impairment elderly with different BDNF Val66Met genotypes", Journal of Alzheimers Disease, 43(1), pp.8~91 (2015)
- Charlene JT, "Interventions for cognitive impairment due to non-localised cancer treatment such as chemotherapy or hormonal therapy", Cochrane Database of Systematic Reviews, 8, pp.CD011325~ (2016)
- Andreas AA, "Either Called “Chemobrain” or “Chemofog,” the Long-Term Chemotherapy-Induced Cognitive Decline in Cancer Survivors Is Real", Journal of Pain and Symptom Management, 41(1), pp.126~139 (2011)
- Ma SQ, "Effects of acupuncture on dementia : An overview of systematic reviews", European Journal of Integrative Medicine, 41, pp.101256~ (2021)
- Wang Z, "Acupuncture modulates resting state hippocampal functional connectivity in Alzheimer disease", PLoS One, 9(3), pp.e91160~ (2014)
- Chatchada Sutalangka, "Laser Acupuncture Improves Memory Impairment in an Animal Model of Alzheimer’s Disease", Journal of Acupuncture & Meridian Studies, 6(5), pp.247~251 (2013), 사단법인약침학회[DOI]
- Peng W, "Acupuncture for vascular dementia", Cochrane Database of Systematic Reviews, 2, pp.CD004987~ (2007)
- Zhou W, "Effects of electroacupuncture on the elderly’s postoperation cognitive dysfunction after general anesthesia", Chin J Phys Med Rehabil, 36, pp.372~375 (2014)
- Moher D, "Preferred reporting items for systematic reviews and meta-analyses : the PRISMA statement", Int J Surg, 8, pp.336~341 (2010)
- Higgins JP, "The Cochrane collaboration’s tool for assessing risk of bias in randomised trials", BMJ, 343, pp.d5928~ (2011)
- Jadad Ar, "Assessing the quality of reports of randomized clinical trials : is blinding necessary?", Conrol Clin Trials, 17(1), pp.1~12 (1996)
- Lin S, "Influences of acupuncture anesthesia on postoperative cognitive dysfunction and S-100β protein level of the elderly patients of colorectal cancer resection", Chinese Acupuncture &Moxibution, 33(1), pp.63~66 (2013)
- Lin S, "Impacts of the different frequencies of electroacupunctrue on cognitive function in patients after abdominal operation under compound anesthesia of acupuncture and drugs", Chinese Acupuncture & Moxibution, 33(12), pp.1109~1112 (2013)
- Ni J, "Effect of Transcutaneous Acupoint Electrical Stimulation on Postoperative Cognitive Function in Elderly Patients Undergoing Laparoscopic Resection of Rectal Cancer", Chinese Heneral Practice, 18(12), pp.1390~1395 (2015)
- Li X, "Effect of transcutaneous electrical acupoint stimulation on postoperative cognitive function in patients undergoing radical thoracoscopic lung cancer operation", Chinese archives of traditional Chinese Medicine, 34(7), pp.1752~1755 (2016)
- Liu Z, "Effect of acupuncture combined with general anesthesia on cognitive function and related inflammatory factors in elderly patients with tumor resection", China medical herald, 14(22), pp.76~79 (2017)
- Tong T, "Efficacy of Acupuncture Therapy for Chemotherapy-Related Cognitive Impairment in Breast Cancer Patients", Clinical research, 24, pp.2919~2927 (2018)
- Wang N, "Combined acupuncture and general anesthesia on immune and cognitive function in elderly patients following subtotal gastrectomy for gastric cancer", ONCOLOGYLETTERS, 15, pp.189~194 (2018)
- Li X, "The effect of transcutaneous electrical acupoint stimulation on postoperative cognitive function in patients undergoing radical thoracoscopic lung cancer operation", Master, pp.2018
- Zhang C, "Clinical Study on Acupuncture Treatment of Yiqi-Tiaoshen Acupoint on Mild Cognitive Impairment Caused by Chemotherapy of Breast Cancer Patients", Guiding Journal of Traditional Chinese Medicine and Pharmacy, 24(9), pp.49~52 (2018)
- Han X, "Effect of acupuncture combined with anesthesia on postoperative cognitive function of elderly patients undergoing bowel cancer resection", Heilongjiang Journal of Traditional Chinese Medicine, 1, pp.68~69 (2018)
- Zhang Z, "Electroacupuncture trigeminal nerve stimulation plus body acupuncture for chemotherapy-induced cognitive impairment in breast cancer patients : An assessor-participant blinded, randomized controlled trial", Brain, Behavior, and Immunity, 88, pp.88~96 (2020)
- Shilling V, "Self-reported cognitive problems in women receiving adjuvant therapy for breast cancer", Eur J of Oncol Nursing, 11, pp.6~15 (2006)
- Vardy J, "Cancer and cancer-therapy related cognitive dysfunction : an international perspective from the Venice cognitive workshop", Ann Oncol, 19, pp.623~629 (2008)
- Hermelink K, "Two different sides of ‘chemobrain’: determinants and nondeterminants of self‐perceived cognitive dysfunction in a prospective, randomized, multi-center study", Psycho-oncology, 19, pp.1321~1328 (2010)
- Varsha D, "Chemotherapy, neurotoxicity, and cognitive changes in breast cancer", Journal of Cancer Research and Therapeutics, 7, pp.264~269 (2011)
- Palmer JL, "Cognitive effects of Tamoxifen in pre-menopausal women with breast cancer compared to healthy controls", Journal of cancer survivorship : research and practice, 2(4), pp.275~282 (2008)
- Denlinger CS, "Survivorship: cognitive function, version 1.2014", Journal of the National Comprehensive Cancer Network : JNCCN, 12(7), pp.976~986 (2014)
- BoykoffN, "Confronting chemobrain : an in-depth look at survivors’ reports of impact on work, social networks, and health care response", Journal of cancer survivorship : research and practice, 3(4), pp.223~232 (2009)
- Wang J, "Acupuncture mechanisms : Anesthesia, analgesia and protection on organ functions", World J Tradit Chin Med, 1, pp.59~66 (2015)
- Gemma M, "Acupuncture accelerates recovery after general anesthesia : A prospective randomized controlled trial", J Integr Med, 13, pp.99~104 (2015)
- Wefel JS, "International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer", The Lancet. Oncology, 12(7), pp.703~708 (2011)
- Janelsins MC, "Prevalence, mechanisms, and management of cancer-related cognitive impairment", International review of psychiatry, 26(1), pp.102~113 (2014)
- Newman MF, "Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery", Stroke, 32, pp.2874~2881 (2001)
- Caza N, "The effects of surgery and anesthesia on memory and cognition", Prog Brain Res, 169, pp.409~422 (2008)
- Cibelli M, "Role of interleukin-1beta in postoperative cognitive dysfunction", Ann Neurol, 68, pp.360~368 (2010)
- Lin D, "Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats", Neuropharmacology, 61, pp.1354~1359 (2011)
- Evered L, "Postoperative cognitive dysfunction is independent of type of surgery and anesthetic", Anesth Analg, 112, pp.1179~1185 (2011)
- 이재우, "60세 이상 환자에서 척추마취 동안 propofol을 이용한 진정 깊이 정도에 따른 수술 후 인지기능장애 발생", Anesthesia and Pain Medicine, 10(3), pp.196~202 (2015), 대한마취통증의학회
- Lin S, "Effect of acupuncture-anesthetic composite anesthesia on the incidence of POCD and TNF-alpha, IL-1beta, IL-6 in elderly patients", chinese journal of integrated traditional and western medicine, 34(7), pp.795~799 (2014)
- Avisar AR, "Chemotherapy-related cognitive impairment : does integrating complementary medicine have something to add? Review of the literature", Breast cancer research and treatment, 136(1), pp.1~7 (2012)
- Johnston MFY, "Acupuncture for chemotherapy-associated cognitive dysfunction : a hypothesis-generating literature review to inform clinical advice", Integrative cancer therapies, 6(1), pp.36~41 (2007)
- Lin R, "Electroacupuncture at the Baihui acupoint alleviates cognitive impairment and exerts neuroprotective effects by modulating the expression and processing of brain-derived neurotrophic factor in APP", PS1 transgenic mice, 2016, pp.13(2), 1611~1617
- Cheng H, "Acupuncture improves cognitive deficits and regulates the brain cell proliferation of SAMP8 mice", Neurosci Letter, 432(2), pp.111~116 (2008)
- Zhao L, "Aging-related changes of triose phosphate isomerase in hippocampus of senescence accelerated mouse and the intervention of acupuncture", Neurosci Lett, 542, pp.59~64 (2013)
- Nie K, "Effect of acupuncture on transmembrane signal pathway in AD mice: an analysis based on lipid-raft proteomics", Chinese Journal of Integrated Traditional and Western Medicine, 34(8), pp.991~996 (2014)
- Wang X, "Effect of electro-acupuncture on neuroplasticity of spinal cord-transected rats", Med Sci Monit, 23, pp.4241~4251 (2017)
- Słowik AJ, "Evaluation of quality of life in women with breast cancer, with particular emphasis on sexual satisfaction, future perspectives and body image, depending on the method of surgery", Psychiatr Pol, 51(5), pp.871~888 (2017)
- Luo D, "Mechanism underlying acupuncture-ameliorated depressive behaviors by enhancing glial glutamate transporter in chronic unpredictable mild stress (CUMS) Rats", Med Sci Monit, 23, pp.3080~3087 (2017)
- He Y, "Effectiveness of acupuncture for cancer pain : Protocol for an umbrella review and meta-analyses of controlled trials", BMJ Open, 7(12), pp.e018494~ (2017)
- Schulz KF, "CONSORT 2010 statement : updated guidelines for reporting parallel group randomised trials", BMJ, 340, pp.c332~ (2010)