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Tribenzylamine Ionophore를 이용한 pH-ISE의 제조 및 임상응용

Preparation and Clinical Application of pH-ISE(Ion Selective Electrode) Based on Tribenzylamine Ionophore

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주제분류기타자연과학

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Abstract

The pH-ISE(ion selective electrode) based on tribenzylamine as a hydrogen ion carrier was prepared and its electrochemical characterization was studied. It responded linearly to hydrogen ions in the range of pH 3.1 - pH 11.0 and the Nernstian slope showed 55.0 mV/pH (at 20 ± 0.2℃), it also showed a fast response time of 8 sec. When it was directly applied to human blood(pH 6.0-8.5), we could get the same satisfying results. A good reproducibility and stability were shown with the precision of 2 mV (±0.1). The pH-ISE based on tribenzylamine exhibited biocompatibility in clinical applications.

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