16종 다용한약재의 산지별 As, Cd, Pb, Co, Cr 농도 및 특성고찰 - 한국과 중국산의 평균농도, 최소-최대농도와 법적 허용농도초과비율을 중심으로 -
As, Cd, Pb, Co, Cr Concentration and Property Evaluation in Frequently Using 16 Oriental Herbal Medicines - Mainly Average, Lowest, Highest Concentration and Percent Exceeding Value of Legal Allowance in Korean and Chinese Origines -
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Objective: Average, lowest, highest concentration and exceeding value of legal allowance of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea (Astragali Radix, Ginseng, Citri Unshii Pericarpium, Aurantii Fructus Immaturus, Angelicae Gigantis Radix, Cnidii Rhizoma, Paeoniae Radix, Rehmanniae Radix Preparata, Zingiberis Rhizoma Crudus, Zizyphi Fructus, Atractylodis Rhizoma Alba, Hoelen, Dioscoreae Rhizoma, Corni Fructus, Schisandrae Fructus, Lycii Fructus) was evaluated according to their origines (korea, china) and property was also discussed according to the medicinally active part and individuals regardless origines. Method: Korean and Chinese herbal medicines were evenly sampled from corresponding country nationwide. Pre-treatment was executed according to the KFDA(Korea Food and Drug Administration) regulation and analysis was performed according to the Korean Environmental Analysis QA/QC. Result: Not much difference was observed according to their origines. However, lowest, highest and percent exceeding value of legal allowance was showed some consistent differences according to the medicinally active part and individuals. Co and Cr was can not be evaluated since their legal regulation was not established yet. Conclusion: The average concentration of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea showed no noticeable difference according to their origines. Regardless the origin, some consistent differences were observed according to the individuals and medicinally active parts.
Abstract
Objective: Average, lowest, highest concentration and exceeding value of legal allowance of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea (Astragali Radix, Ginseng, Citri Unshii Pericarpium, Aurantii Fructus Immaturus, Angelicae Gigantis Radix, Cnidii Rhizoma, Paeoniae Radix, Rehmanniae Radix Preparata, Zingiberis Rhizoma Crudus, Zizyphi Fructus, Atractylodis Rhizoma Alba, Hoelen, Dioscoreae Rhizoma, Corni Fructus, Schisandrae Fructus, Lycii Fructus) was evaluated according to their origines (korea, china) and property was also discussed according to the medicinally active part and individuals regardless origines. Method: Korean and Chinese herbal medicines were evenly sampled from corresponding country nationwide. Pre-treatment was executed according to the KFDA(Korea Food and Drug Administration) regulation and analysis was performed according to the Korean Environmental Analysis QA/QC. Result: Not much difference was observed according to their origines. However, lowest, highest and percent exceeding value of legal allowance was showed some consistent differences according to the medicinally active part and individuals. Co and Cr was can not be evaluated since their legal regulation was not established yet. Conclusion: The average concentration of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea showed no noticeable difference according to their origines. Regardless the origin, some consistent differences were observed according to the individuals and medicinally active parts.
참고문헌 (20)
- Sun-Dong Lee, "Urine and Hair Metal Correlation in Subjects with Long Term Intake of Herbal Medicine", Journal of Oriental Preventive Medical Society, 6(1), pp.129~139 (2002)
- 이선동, "한약재복용으로 인한 한국인의 중금속 섭취량 및 위해성 평가연구", 한국환경보건학회지, 36(1), pp.14~19 (2010), 한국환경보건학회
- 이정렬, "五積散을 투여한 흰쥐의 혈액중 금속농도 비교에 관한 연구< 용량-반응관계와 기전을 중심으로 >", 대한한의학회지, 23(1), pp.67~82 (2002), 대한한의학회
- Massaro, E.J., "Handbook of Human Toxicology", pp.149~188 (1990), Boca Raton Press
- "보건복지부 고시 1996-26호, 한약재 품질 및유통관리", ~ (1996)
- 식품의약품안전청, "생약 등의 잔류․오염물질기준 및 시험방법 개정고시 제2011-42호(2011.08. 22, 개정)", ~ (2011)
- Joint FAO, "Safety Evaluation of Certain Food Additives and Contaminants", pp.2000, WHO Expert Committee on Food Additives(JECFA)
- Suk-Kyung Ko, "Contents of Heavy Metals of Commercial Herbal Medicines in Seoul Area", Report of Seoul Institute of Health & Environment, 39, pp.31~43 (2003)
- Young Shin, "Monitoring of Heavy Metal in Herbal Medicines from Markets in Seoul by ICPMS", Report of Seoul Institute of Health & Environment, 43, pp.226~246 (2007)
- Eun-Jung Han, "Heavy Metal Contents of Herbal Medicines in Common Use for Food and Medicine from Markets in Seoul", Report of Seoul Institute of Health & Environment, 44, pp.126~139 (2008)
- 한방 의료이용 및 한약소비 실태조사, "한국보건사회연구원", 보건복지부, 328~348 (2011)
- 환경부, "환경시험․검사 QA", QC 핸드북, 2011
- 정삼주, "한약재의 약용부위별 중금속 함량 및 탕 액에서의 이행률 조사", 한국식품위생안전성학회지, 25(4), pp.402~409 (2010), 한국식품위생안전성학회
- 박문기, "경북북부지역 한약재와 재배토양중의 중금속과의 상관관계", 한국환경과학회지, 14(2), pp.185~192 (2005), 한국환경과학회
- Sang-Baek Han, "Heavy Metal Concentrations of Herbal Medicines Produced in Korea, China and Other Countries", 석사, Oriental Medicine, pp.1998
- 정일형, "한약 및 한약제제의 안전성 평가", 한국식품위생안전성학회지, 25(3), pp.232~237 (2010), 한국식품위생안전성학회
- 이향희, "광주지역 유통 한약재의 유해물질 잔류실태조사", 한국식품위생안전성학회지, 25(2), pp.83~90 (2010), 한국식품위생안전성학회
- 이미경, "유통 한약재의 중금속 함량 조사", 한국식품저장유통학회지, 15(2), pp.253~260 (2008), 한국식품저장유통학회
- 중약대사전 편찬위원회, "중약대사전 1권", pp.888~ (2004), 정담
- 김광중, "경북북부지역 재배한약재와 토양의 중금속 함량연구", 동의생리병리학회지, 17(3), pp.1419~1426 (2003), 대한동의병리학회