국내 유통 한약재의 중금속 함량 모니터링 -서울과 대구지역 한약재 중심으로 -
Monitoring of Heavy Metal Contents in Commercial Herbal Medicines in Korea: Cultivated Herbal Medicines in the Seoul and Daegu Areas
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초록
Objectives: This study was conducted to determine the heavy metal contents in commercial herbal medicinesin Korea. Methods: Monitoring of lead, arsenic, cadmium and mercury was carried out on 116 samples of eleven typesof herbal medicines. Among the total samples, 71 samples were domestic and 45 were imported. The sampleswere digested using the microwave method. The heavy metal contents were measured by inductively coupledplasma atomic emission spectrometry (ICP-AES) and a mercury analyzer. ICP-AES was used to analyze lead,arsenic cadmium. Mercury was analyzed by the amalgamation method. Results: The mean values of the heavy metal contents in the herbal medicines were Pb 0.64mg/kg, As 0.26mg/kg,Cd 0.07mg/kg and Hg 0.004mg/kg. Of the total samples, one violated the MFDS (Ministry of Food and Drug Safety)regulatory guidance on heavy metals in herbal medicines. Lead was detected at more than 5mg/kg in one sample. Themeasured values of arsenic, cadmium and mercury in the herbal medicines showed levels lower than therecommended levels for herbal medicines in MFDS regulatory guidance. In the comparison of domestic samples withimported herbal medicines, it was found that one domestic sample surpassed the maximum residue limits for lead. Conclusion: These results will be used to establish the regulation and control of heavy metal contents in herbalmedicines. In addition, continuous monitoring is needed to ensure confidence in and the safety of these herbalmedicines.
Abstract
Objectives: This study was conducted to determine the heavy metal contents in commercial herbal medicinesin Korea. Methods: Monitoring of lead, arsenic, cadmium and mercury was carried out on 116 samples of eleven typesof herbal medicines. Among the total samples, 71 samples were domestic and 45 were imported. The sampleswere digested using the microwave method. The heavy metal contents were measured by inductively coupledplasma atomic emission spectrometry (ICP-AES) and a mercury analyzer. ICP-AES was used to analyze lead,arsenic cadmium. Mercury was analyzed by the amalgamation method. Results: The mean values of the heavy metal contents in the herbal medicines were Pb 0.64mg/kg, As 0.26mg/kg,Cd 0.07mg/kg and Hg 0.004mg/kg. Of the total samples, one violated the MFDS (Ministry of Food and Drug Safety)regulatory guidance on heavy metals in herbal medicines. Lead was detected at more than 5mg/kg in one sample. Themeasured values of arsenic, cadmium and mercury in the herbal medicines showed levels lower than therecommended levels for herbal medicines in MFDS regulatory guidance. In the comparison of domestic samples withimported herbal medicines, it was found that one domestic sample surpassed the maximum residue limits for lead. Conclusion: These results will be used to establish the regulation and control of heavy metal contents in herbalmedicines. In addition, continuous monitoring is needed to ensure confidence in and the safety of these herbalmedicines.
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