Prenatally detected thoracic neuroblastoma
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초록
Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cellsof the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracicneuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma withmassive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referredto our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicionof teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the masswas considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheralcalcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excisionbiopsy.
Abstract
Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cellsof the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracicneuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma withmassive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referredto our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicionof teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the masswas considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheralcalcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excisionbiopsy.
참고문헌 (15)
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