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Glutaraldehycle를 이용한 설파제의 지속성과 항균성

A study on the Durability and Synthesis of Sulfa AgentsUsing Glutarldehyde

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Abstract

Dual actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against Gram(+) and Gram(-) of 4 strains and a long durability supposing that the stomach and blood.

참고문헌 (4)

  1. "Drug parameters imporyant for transdermal delivery", pp.3~ (1997), CRC Press
  2. "Medical applications of controlled release", pp.2~8 (1994), CRC Press
  3. "藥物送達法, 廣川書店", pp.225~231 (2000)
  4. "Methods of Drug Delivery", pp.82~85 (1996), Pergamon Press

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