Colon Capsule Endoscopy: Indications, Findings, and Complications – Data from a Prospective German Colon Capsule Registry Trial (DEKOR)
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Background/Aims: Reliable and especially widely accepted preventive measures are crucial to further reduce the incidenceof colorectal cancer (CRC). Colon capsule endoscopy (CCE) might increase the screening numbers among patients unable orunwilling to undergo conventional colonoscopy. This registry trial aimed to document and determine the CCE indications, findings,complications, and adverse events in outpatient practices and clinics throughout Germany. Methods: Patients undergoing CCE between 2010 and 2015 were enrolled in this prospective multicenter registry trial at six Germancenters. Patient demographics, outcomes, and complications were evaluated. Results: A total of 161 patients were included. Of the CCE evaluations, 111 (68.9%) were considered successful. Pathological findingsin the colon (n=92, 60.1%) and in the remaining gastrointestinal tract (n=38, 24.8%) were recorded. The main finding was thepresence of polyps (n=52, 32.3%). Furthermore, five carcinomas (3.1%) were detected and histologically confirmed later. Adequatebowel cleanliness was more likely to be achieved in the outpatient setting (p<0.0001). Interestingly, 85 patients (55.6%) chose toundergo CCE based on personal motivation. Conclusions: CCE seems to be a reliable and safe endoscopic tool for screening for CRC and detecting other diseases. Its patientacceptance and feasibility seems to be high, especially in the outpatient setting.
Abstract
Background/Aims: Reliable and especially widely accepted preventive measures are crucial to further reduce the incidenceof colorectal cancer (CRC). Colon capsule endoscopy (CCE) might increase the screening numbers among patients unable orunwilling to undergo conventional colonoscopy. This registry trial aimed to document and determine the CCE indications, findings,complications, and adverse events in outpatient practices and clinics throughout Germany. Methods: Patients undergoing CCE between 2010 and 2015 were enrolled in this prospective multicenter registry trial at six Germancenters. Patient demographics, outcomes, and complications were evaluated. Results: A total of 161 patients were included. Of the CCE evaluations, 111 (68.9%) were considered successful. Pathological findingsin the colon (n=92, 60.1%) and in the remaining gastrointestinal tract (n=38, 24.8%) were recorded. The main finding was thepresence of polyps (n=52, 32.3%). Furthermore, five carcinomas (3.1%) were detected and histologically confirmed later. Adequatebowel cleanliness was more likely to be achieved in the outpatient setting (p<0.0001). Interestingly, 85 patients (55.6%) chose toundergo CCE based on personal motivation. Conclusions: CCE seems to be a reliable and safe endoscopic tool for screening for CRC and detecting other diseases. Its patientacceptance and feasibility seems to be high, especially in the outpatient setting.
참고문헌 (31)
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