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논문KCI 등재

APTT 결과에서 기준치 아래의 표시를 보이는 것의 대책

Countermeasures of Specimens Showing below Reference Value in APTT Result

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초록

The activated partial thromboplastin time (APTT) is used primarily to evaluate coagulation abnormalities in the intrinsic pathway. The proper specimen is very important factor for precise results of blood coagulation analysis. The objective of this study was to get to the conclusion of whether to analyze again and to collect blood sample over again when APTT result shows below the reference value. We evaluated 126 samples showing a value below 20.0 sec at ATPT result, which consist of 48 males and 78 females candidates during night duty from March 2012 to December 2012. Average comparisons of APTT result between first and retested analysis among study subjects were significantly different in male samples. APTT results comparison of recollected subjects among clotted samples were also significantly different with both sexes (p<0.000). We suggest that we should carefully check the samples to get accurate results and collect samples again in case of only obtaining improper samples; even though the APTT result show below reference value.

Abstract

The activated partial thromboplastin time (APTT) is used primarily to evaluate coagulation abnormalities in the intrinsic pathway. The proper specimen is very important factor for precise results of blood coagulation analysis. The objective of this study was to get to the conclusion of whether to analyze again and to collect blood sample over again when APTT result shows below the reference value. We evaluated 126 samples showing a value below 20.0 sec at ATPT result, which consist of 48 males and 78 females candidates during night duty from March 2012 to December 2012. Average comparisons of APTT result between first and retested analysis among study subjects were significantly different in male samples. APTT results comparison of recollected subjects among clotted samples were also significantly different with both sexes (p<0.000). We suggest that we should carefully check the samples to get accurate results and collect samples again in case of only obtaining improper samples; even though the APTT result show below reference value.

참고문헌 (10)

  1. Ambrus JL, "Effect of antifibrinolytic agents and estrogens on blood loss and blood coagulation factors during open heart surgery", J Med, 2, pp.65~81 (1971)
  2. Beckala HR, "Comparison of five manually operated coagulation instruments", Am J Clinical Pathol, 70, pp.71~75 (1978)
  3. Kamal AH, "How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults", Mayo Clin Proc, 82, pp.864~873 (2007)
  4. Lewis SM, "Quality assurance in hematology", pp.113~143 (1993), Korea Medical
  5. Marlar RA, "Comparioson of the sensitivity of commercial APTT reagents in the detection of the mild coagulopathies", Am J Clinical Pathol, 82, pp.436~439 (1984)
  6. Matsuo N, "Overview of the Sysmex CA-7000 automated coagulation analyzer", Sysmex J Int, 9, pp.170~174 (1999)
  7. Prasad RN, "Effect on hemostasis after two-year use of low dose combined oral contraceptives with gestodene or levonorgestrel", Clin App Thromb Hemost, 51, pp.60~70 (1999)
  8. Suchman AL, "Diagnostic uses of the activated partial thromboplastin time and prothrombin time", Ann Intern Med, 104, pp.810~816 (1986)
  9. Kasai T, "Principles of analysis by the automated coagulation analyzer CA-6000TM", Sysmex Journal International, 7, pp.43~45 (1997)
  10. 이유경, "자동응고분석기 CA-1500과 CA-7000의 평가", 임상 병리와 정도관리, 23, pp.253~258 (2001)

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