본문 바로가기
KERD
논문KCI 등재

Intermittent Fasting: a Promising Approach for Preventing Vascular Dementia

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Vascular dementia is the most common neuropsychiatric syndrome and is characterized by synaptic dysfunction, neuroinflammation, and cognitive dysfunction. Vascular dementia is associated with various environmental, genetic, and lifestyle risk factors. Recent research has focused on the association between vascular dementia and dietary patterns, suggesting that dietary regulation leads to better control of energy metabolism, improvements in brain insulin resistance, and the suppression of neuroinflammation. Intermittent fasting is a calorie-restriction method known to be more effective in promoting fat loss and regulating the impairment of glucose metabolism as compared with other dietary restriction regimens. Herein, the authors review the effects of intermittent fasting with regard to vascular dementia based on recent evidence and propose that intermittent fasting could be a therapeutic approach for ameliorating vascular dementia pathology and preventing its onset.

Abstract

Vascular dementia is the most common neuropsychiatric syndrome and is characterized by synaptic dysfunction, neuroinflammation, and cognitive dysfunction. Vascular dementia is associated with various environmental, genetic, and lifestyle risk factors. Recent research has focused on the association between vascular dementia and dietary patterns, suggesting that dietary regulation leads to better control of energy metabolism, improvements in brain insulin resistance, and the suppression of neuroinflammation. Intermittent fasting is a calorie-restriction method known to be more effective in promoting fat loss and regulating the impairment of glucose metabolism as compared with other dietary restriction regimens. Herein, the authors review the effects of intermittent fasting with regard to vascular dementia based on recent evidence and propose that intermittent fasting could be a therapeutic approach for ameliorating vascular dementia pathology and preventing its onset.

참고문헌 (55)

  1. Livingston G, "Dementia prevention, intervention, and care", Lancet, 390, pp.2673~2734 (2017)
  2. Wortmann M, "Dementia: a global health priority - highlights from an ADI and World Health Organization report", Alzheimers Res Ther, 4, pp.40~ (2012)
  3. Masters CL, "Alzheimer's disease", Nat Rev Dis Primers, 1, pp.15056~ (2015)
  4. Cummings JL, "Alzheimer's disease", N Engl J Med, 351, pp.56~67 (2004)
  5. McKhann GM, "The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease", Alzheimers Dement, 7, pp.263~269 (2011)
  6. Warren JD, "Clinical review. Frontotemporal dementia", BMJ, 347, pp.f4827~ (2013)
  7. Dong Y, "Patterns of neuropsychological impairment in Alzheimer's disease and mixed dementia", J Neurol Sci, 333, pp.5~8 (2013)
  8. Bussè C, "Specific verbal memory measures may distinguish Alzheimer's disease from dementia with lewy bodies", J Alzheimers Dis, 59, pp.1009~1015 (2017)
  9. Scheltens P, "Alzheimer's disease", Lancet, 388, pp.505~517 (2016)
  10. Bhaskar K, "Regulation of tau pathology by the microglial fractalkine receptor", Neuron, 68, pp.19~31 (2010)
  11. Gorelick PB, "Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association", American Stroke Association, 2011, pp.42, 2672~2713
  12. Forette F, "Detection of cerebral aging, an absolute need: predictive value of cognitive status", Eur Neurol, 39(Suppl 1), pp.2~6 (1998)
  13. Bell RD, "Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging", Neuron, 68, pp.409~427 (2010)
  14. Gupta A, "Mid-life cardiovascular risk impacts memory function: the Framingham Offspring study", Alzheimer Dis Assoc Disord, 29, pp.117~123 (2015)
  15. Sun MK, "Links between Alzheimer's disease and diabetes", Timely Top Med Cardiovasc Dis, 10, pp.E24~ (2006)
  16. Aridi YS, "The association between the Mediterranean dietary pattern and cognitive health: a systematic review", Nutrients, 9, pp.E674~ (2017)
  17. Bordone L, "Calorie restriction, SIRT1 and metabolism: understanding longevity", Nat Rev Mol Cell Biol, 6, pp.298~305 (2005)
  18. Seimon RV, "Do intermittent diets provide physiological benefits over continuous diets for weight loss? A systematic review of clinical trials", Mol Cell Endocrinol, 418, pp.153~172 (2015)
  19. Davis CS, "Intermittent energy restriction and weight loss: a systematic review", Eur J Clin Nutr, 70, pp.292~299 (2016)
  20. Ganesan K, "Intermittent fasting: the choice for a healthier lifestyle", Cureus, 10, pp.e2947~ (2018)
  21. Puttonen S, "Effect of shiftwork on systemic markers of inflammation", Chronobiol Int, 28, pp.528~535 (2011)
  22. Schafer MJ, "Calorie restriction suppresses age-dependent hippocampal transcriptional signatures", PLoS One, 10, pp.e0133923~ (2015)
  23. Shin BK, "Intermittent fasting protects against the deterioration of cognitive function, energy metabolism and dyslipidemia in Alzheimer's disease-induced estrogen deficient rats", Exp Biol Med (Maywood), 243, pp.334~343 (2018)
  24. Zhang J, "Intermittent fasting protects against Alzheimer's disease possible through restoring aquaporin-4 polarity", Front Mol Neurosci, 10, pp.395~ (2017)
  25. Wang X, "β hydroxybutyrate levels in serum and cerebrospinal fluid under ketone body metabolism in rats", Exp Anim, 66, pp.177~182 (2017)
  26. Vera E, "Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity", PLoS One, 8, pp.e53760~ (2013)
  27. Fann DY, "Intermittent fasting attenuates inflammasome activity in ischemic stroke", Exp Neurol, 257, pp.114~119 (2014)
  28. Vasconcelos AR, "Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment", J Neuroinflammation, 11, pp.85~ (2014)
  29. Shojaie M, "Intermittent fasting could ameliorate cognitive function against distress by regulation of inflammatory response pathway", J Adv Res, 8, pp.697~701 (2017)
  30. Longo VD, "Fasting: molecular mechanisms and clinical applications", Cell Metab, 19, pp.181~192 (2014)
  31. Jeong JH, "Intermittent fasting is neuroprotective in focal cerebral ischemia by minimizing autophagic flux disturbance and inhibiting apoptosis", Exp Ther Med, 12, pp.3021~3028 (2016)
  32. Cohen SM, "Evolutionary and functional perspectives on signaling from neuronal surface to nucleus", Biochem Biophys Res Commun, 460, pp.88~99 (2015)
  33. Hirano Y, "Fasting launches CRTC to facilitate long-term memory formation in Drosophila", Science, 339, pp.443~446 (2013)
  34. Fusco S, "A role for neuronal cAMP responsiveelement binding (CREB)-1 in brain responses to calorie restriction", Proc Natl Acad Sci U S A, 109, pp.621~626 (2012)
  35. Kondo M, "The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects", Mol Psychiatry, 20, pp.1428~1437 (2015)
  36. Dasgupta A, "Intermittent fasting promotes prolonged associative interactions during synaptic tagging", capture by altering the metaplastic properties of the CA1hippocampal neurons, 2018, pp.154, 70~77
  37. Wang M, "Fasting induces a form of autonomic synaptic plasticity that prevents hypoglycemia", Proc Natl Acad Sci U S A, 113, pp.E3029~E3038 (2016)
  38. Cabral-Costa JV, "Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice", Sci Rep, 8, pp.8595~ (2018)
  39. Gao YZ, "Regional cerebral blood flow and cerebrovascular reactivity in Alzheimer's disease and vascular dementia assessed by arterial spinlabeling magnetic resonance imaging", Curr Neurovasc Res, 10, pp.49~53 (2013)
  40. Iadecola C, "The pathobiology of vascular dementia", Neuron, 80, pp.844~866 (2013)
  41. Hughes TM, "Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study", Neurology, 90, pp.e1248~e1256 (2018)
  42. Tarantini S, "Impaired neurovascular coupling in aging and Alzheimer's disease: contribution of astrocyte dysfunction and endothelial impairment to cognitive decline", Exp Gerontol, 94, pp.52~58 (2017)
  43. Fontana L, "Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans", Proc Natl Acad Sci U S A, 101, pp.6659~6663 (2004)
  44. Headland ML, "Effect of intermittent energy restriction on flow mediated dilatation, a measure of endothelial function: a short report", Int J Environ Res Public Health, 15, pp.E1166~ (2018)
  45. Erdem Y, "The effect of intermittent fasting on blood pressure variability in patients with newly diagnosed hypertension or prehypertension", J Am Soc Hypertens, 12, pp.42~49 (2018)
  46. Nematy M, "Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study", Nutr J, 11, pp.69~ (2012)
  47. Antoni R, "Investigation into the acute effects of total and partial energy restriction on postprandial metabolism among overweight", obese participants, 2016, pp.115, 951~959
  48. Anson RM, "Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake", Proc Natl Acad Sci U S A, 100, pp.6216~6220 (2003)
  49. Thompson PM, "Tracking Alzheimer's disease", Ann N Y Acad Sci, 1097, pp.183~214 (2007)
  50. Wolf SA, "Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23model of Alzheimer's disease", Biol Psychiatry, 60, pp.1314~1323 (2006)
  51. Wang Z, "Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis", J Cereb Blood Flow Metab, 32, pp.387~398 (2012)
  52. Garza JC, "Leptin increases adult hippocampal neurogenesis in vivo and in vitro", J Biol Chem, 283, pp.18238~18247 (2008)
  53. Hu Y, "Intermittent fasting pretreatment prevents cognitive impairment in a rat model of chronic cerebral hypoperfusion", J Nutr, 147, pp.1437~1445 (2017)
  54. Hu Y, "Postoperative intermittent fasting prevents hippocampal oxidative stress and memory deficits in a rat model of chronic cerebral hypoperfusion", Eur J Nutr, 58, pp.423~432 (2019)
  55. Singh R, "Middle age onset shortterm intermittent fasting dietary restriction prevents brain function impairments in male Wistar rats", Biogerontology, 16, pp.775~788 (2015)

관련 논문AI추천

이 간행물의 다른 논문 (6건)