Preventive Measures against the Development of Dementia in Old Age
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Dementia is a neurological condition characterized by numerous types of central nervous system diseases, which gradually deteriorates an individual’s reasoning, rational thinking, and judgment abilities. As a serious public health concern that currently affects more than 50 million older adults, dementia is one of the most significant causes of incapacity, disability, and dependency among older adults. As new cases are expected to increase expo-nentially in the next three decades, dementia, which is not a normal feature of healthy aging despite the fact that it generally affects older adults disproportionately, requires enormous management and care efforts due to its associ-ated socioeconomic, psychological, and physical burdens that involve the patient, their caregivers, guardians, fami-ly members, and society at large. Presently, there is no cure for dementia; however, this condition could be prevent-ed. This narrative review aimed to provide a broad overview of studies detailing the alternative lifestyle modifica-tion-centered preventive measures against dementia. A comprehensive search of key databases to find articles re-lated to this topic revealed that participating in regular physical activities, healthy eating and dieting, avoiding all forms of smoking, avoiding air pollutants, halting or reducing alcohol consumption, exercising the mind and being socially dynamic, getting enough rest and establishing good sleeping habits, infection prevention, stress preven-tion, avoidance of injuries, preventing the effects of social isolation and lockdowns, continuing education, and de-pression prevention are protective measures against the development of dementia.
Abstract
Dementia is a neurological condition characterized by numerous types of central nervous system diseases, which gradually deteriorates an individual’s reasoning, rational thinking, and judgment abilities. As a serious public health concern that currently affects more than 50 million older adults, dementia is one of the most significant causes of incapacity, disability, and dependency among older adults. As new cases are expected to increase expo-nentially in the next three decades, dementia, which is not a normal feature of healthy aging despite the fact that it generally affects older adults disproportionately, requires enormous management and care efforts due to its associ-ated socioeconomic, psychological, and physical burdens that involve the patient, their caregivers, guardians, fami-ly members, and society at large. Presently, there is no cure for dementia; however, this condition could be prevent-ed. This narrative review aimed to provide a broad overview of studies detailing the alternative lifestyle modifica-tion-centered preventive measures against dementia. A comprehensive search of key databases to find articles re-lated to this topic revealed that participating in regular physical activities, healthy eating and dieting, avoiding all forms of smoking, avoiding air pollutants, halting or reducing alcohol consumption, exercising the mind and being socially dynamic, getting enough rest and establishing good sleeping habits, infection prevention, stress preven-tion, avoidance of injuries, preventing the effects of social isolation and lockdowns, continuing education, and de-pression prevention are protective measures against the development of dementia.
참고문헌 (103)
- "Dementia" (2015)[URL]
- "Dementia" (2019)[URL]
- "What is dementia? symptoms, types, and diagnosis" (2019)[URL]
- "What is dementia?" (2019)[URL]
- "Dementia statistics" (2020)[URL]
- "Global prevalence" (2018)[URL]
- Sadock BJ, "Kaplan & Sadock’s concise textbook of clinical psychiatry", pp.2008, Wolters Kluwer
- Alty J, "Exercise and dementia prevention", Pract Neurol, 20, pp.234~240 (2020)
- Bertram S, "Exercise for the diabetic brain : how physical training may help prevent dementia and Alzheimer’s disease in T2DM patients", Endocrine, 53, pp.350~363 (2016)
- Lautenschlager NT, "Physical activity for cognitive health : what advice can we give to older adults with subjective cognitive decline and mild cognitive impairment?", Dialogues Clin Neurosci, 21, pp.61~68 (2019)
- Liu IT, "Therapeutic effects of exercise training on elderly patients with dementia : a randomized controlled trial", Arch Phys Med Rehabil, 101, pp.762~769 (2020)
- Bossers WJ, "A 9-week aerobic and strength training program improves cognitive and motor function in patients with dementia : a randomized, controlled trial", Am J Geriatr Psychiatry, 23, pp.1106~1116 (2015)
- Nuzum H, "Potential benefits of physical activity in MCI and dementia", Behav Neurol, 2020, pp.7807856~ (2020)
- Ayenigbara IO, "The contributions of physical activity and fitness for the optimal health and wellness of the elderly people", J Gerontol Geriatr, 68, pp.40~46 (2020)
- Ngandu T, "A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people(FINGER) : a randomized controlled trial", Lancet, 385, pp.2255~2263 (2015)
- Rosenberg A, "Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics : the FINGER trial", Alzheimers Dement, 14, pp.263~270 (2018)
- Kulmala J, "The effect of multidomain lifestyle intervention on daily functioning in older people", J Am Geriatr Soc, 67, pp.1138~1144 (2019)
- Sink KM, "Effect of a 24-month physical activity intervention vs health education on cognitive outcomes in sedentary older adults : the LIFE randomized trial", JAMA, 314, pp.781~790 (2015)
- Ayenigbara I, "The role of healthy nutrition and diet in the prevention of non-communicable diseases among the aged", Geriatr Care, 5, pp.7961~ (2019)
- Glabska D, "Fruit and vegetable intake and mental health in adults : a systematic review", Nutrients, 12, pp.115~ (2020)
- Chou YC, "Association of diet quality and vegetable variety with the risk of cognitive decline in Chinese older adults", Nutrients, 11, pp.1666~ (2019)
- Uenobe M, "Effect of continuous dewaxed brown rice ingestion on the cognitive function of elderly individuals", J Nutr Sci Vitaminol (Tokyo), 65(Supplement), pp.S122~S124 (2019)
- Munoz-Garcia MI, "“A priori” dietary patterns and cognitive function in the SUN project", Neuroepidemiology, 54, pp.45~57 (2020)
- Hosking DE, "MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study", Alzheimers Dement, 15, pp.581~589 (2019)
- Solfrizzi V, "Diet and Alzheimer’s disease risk factors or prevention : the current evidence", Expert Rev Neurother, 11, pp.677~708 (2011)
- Samadi M, "Dietary pattern in relation to the risk of Alzheimer’s disease : a systematic review", Neurol Sci, 40, pp.2031~2043 (2019)
- Wallin C, "Alzheimer’s disease and cigarette smoke components : effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV)ions on amyloid-β peptide aggregation", Sci Rep, 7, pp.14423~ (2017)
- Calderon-Garciduenas L, "Smoking and cerebral oxidative stress and air pollution: a dreadful equation with particulate matter involved and one more powerful reason not to smoke anything!", J Alzheimers Dis, 54, pp.109~112 (2016)
- Durazzo TC, "Active cigarette smoking in cognitively-normal elders and probable Alzheimer’s disease is associated with elevated cerebrospinal fluid oxidative stress biomarkers", J Alzheimers Dis, 54, pp.99~107 (2016)
- Durazzo TC, "Smoking and increased Alzheimer’s disease risk: a review of potential mechanisms", Alzheimers Dement, 10(3Suppl), pp.S122~S145 (2014)
- Swan GE, "The effects of tobacco smoke and nicotine on cognition and the brain", Neuropsychol Rev, 17, pp.259~273 (2007)
- Tavee J, "Smoking cessation for the neurologic patient", Neurol Clin Pract, 2, pp.112~121 (2012)
- Peters R, "Air pollution and dementia : a systematic review", J Alzheimers Dis, 70(s1), pp.S145~S163 (2019)
- Chen H, "Exposure to ambient air pollution and the incidence of dementia : a population-based cohort study", Environ Int, 108, pp.271~277 (2017)
- Carey IM, "Are noise and air pollution related to the incidence of dementia? : a cohort study in London, England", BMJ Open, 8, pp.e022404~ (2018)
- Cerza F, "Long-term exposure to air pollution and hospitalization for dementia in the Rome longitudinal study", Environ Health, 18, pp.72~ (2019)
- Iaccarino L, "Association between ambient air pollution and amyloid positron emission tomography positivity in older adults with cognitive impairment", JAMA Neurol, 78, pp.197~207 (2021)
- Roberts RO, "Prevalence and outcomes of amyloid positivity among persons without dementia in a longitudinal, population-based setting", JAMA Neurol, 75, pp.970~979 (2018)
- Rao R, "Alcohol use disorders and the brain", Addiction, 115, pp.1580~1589 (2020)
- Rehm J, "Alcohol use and dementia : a systematic scoping review", Alzheimers Res Ther, 11, pp.1~ (2019)
- Hoffman JL, "Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer’s disease", Int Rev Neurobiol, 148, pp.169~230 (2019)
- Sullivan EV, "Brain-behavior relations and effects of aging and common comorbidities in alcohol use disorder : a review", Neuropsychology, 33, pp.760~780 (2019)
- Sabia S, "Alcohol consumption and risk of dementia : 23 year follow-up of Whitehall II cohort study", BMJ, 362, pp.k2927~ (2018)
- Koch M, "Alcohol consumption and risk of dementia and cognitive decline among older adults with or without mild cognitive impairment", JAMA Netw Open, 2, pp.e1910319~ (2019)
- Zhang R, "Association of low to moderate alcohol drinking with cognitive functions from middle to older age among US adults", JAMA Netw Open, 3, pp.e207922~ (2020)
- Wang HX, "Late-life engagement in social and leisure activities is associated with a decreased risk of dementia : a longitudinal study from the Kungsholmen project", Am J Epidemiol, 155, pp.1081~1087 (2002)
- Marseglia A, "Participating in mental, social, and physical leisure activities and having a rich social network reduce the incidence of diabetes-related dementia in a cohort of Swedish older adults", Diabetes Care, 42, pp.232~239 (2019)
- Yates LA, "Cognitive leisure activities and future risk of cognitive impairment and dementia : systematic review and meta-analysis", Int Psychogeriatr, 28, pp.1791~1806 (2016)
- Stern C, "Cognitive leisure activities and their role in preventing dementia : a systematic review", Int J Evid Based Healthc, 8, pp.2~17 (2010)
- Kim MJ, "Relationships between cognitive leisure activities and cognitive function in older adults with depressive symptoms : a cross-sectional study", BMJ Open, 10, pp.e032679~ (2020)
- Ching-Teng Y, "Effect of board game activities on cognitive function improvement among older adults in adult day care centers", Soc Work Health Care, 58, pp.825~838 (2019)
- Narme P, "Benefits of game-based leisure activities in normal aging and dementia", Geriatr Psychol Neuropsychiatr Vieil, 14, pp.420~428 (2016)
- Iizuka A, "Can cognitive leisure activity prevent cognitive decline in older adults? : a systematic review of intervention studies", Geriatr Gerontol Int, 19, pp.469~482 (2019)
- Bah TM, "Sleep as a therapeutic target in the aging brain", Neurotherapeutics, 16, pp.554~568 (2019)
- Ayenigbara IO, "Gaming disorder and effects of gaming on health : an overview", J Addict Med Ther Sci, 4, pp.1~3 (2017)
- Mander BA, "Sleep : a novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer’s disease?", Trends Neurosci, 39, pp.552~566 (2016)
- Kent BA, "Sleep and hippocampal neurogenesis : implications for Alzheimer’s disease", Front Neuroendocrinol, 45, pp.35~52 (2017)
- Irwin MR, "Implications of sleep disturbance and inflammation for Alzheimer’s disease dementia", Lancet Neurol, 18, pp.296~306 (2019)
- Minakawa EN, "Sleep disturbance as a potential modifiable risk factor for Alzheimer’s disease", Int J Mol Sci, 20, pp.803~ (2019)
- Lee JE, "Effect of poor sleep quality on subjective cognitive decline(SCD)or SCD-related functional difficulties : results from 220, 000 nationwide general populations without dementia", J Affect Disord, 260, pp.32~37 (2020)
- Chen JC, "Sleep duration, cognitive decline, and dementia risk in older women", Alzheimers Dement, 12, pp.21~33 (2016)
- Xu W, "Sleep problems and risk of allcause cognitive decline or dementia : an updated systematic review and meta-analysis", J Neurol Neurosurg Psychiatry, 91, pp.236~244 (2020)
- Carvalho DZ, "Association of excessive daytime sleepiness with longitudinal β-amyloid accumulation in elderly persons without dementia", JAMA Neurol, 75, pp.672~680 (2018)
- Spira AP, "Excessive daytime sleepiness and napping in cognitively normal adults : associations with subsequent amyloid deposition measured by PiB PET", Sleep, 41, pp.zsy152~ (2018)
- Culebras A, "Sleep apnea is a risk factor for stroke and vascular dementia", Curr Neurol Neurosci Rep, 18, pp.53~ (2018)
- Ding X, "Self-reported sleep apnea and dementia risk : findings from the prevention of Alzheimer’s disease with vitamin E and selenium trial", J Am Geriatr Soc, 64, pp.2472~2478 (2016)
- Kitamura T, "Insomnia and obstructive sleep apnea as potential triggers of dementia : is personalized prediction and prevention of the pathological cascade applicable?", EPMA J, 11, pp.355~365 (2020)
- Sierra C, "Hypertension and the risk of dementia", Front Cardiovasc Med, 7, pp.5~ (2020)
- Zhou Z, "Low-density lipoprotein cholesterol and Alzheimer’s disease : a systematic review and meta-analysis", Front Aging Neurosci, 12, pp.5~ (2020)
- Ayenigbara IO, "The accumulation of visceral fat and preventive measures among the elderly", Cardiovasc Innov Appl, 4, pp.279~285 (2020)
- Polis B, "Role of the metabolism of branched-chain amino acids in the development of Alzheimer’s disease and other metabolic disorders", Neural Regen Res, 15, pp.1460~1470 (2020)
- Kunelskaya NL, "Presbyacusis", Vestn Otorinolaringol, 84, pp.67~71 (2019)
- Tsolaki F, "Helicobacter pylori infection, dementia and primary open-angle glaucoma : are they connected?", BMC Ophthalmol, 15, pp.24~ (2015)
- Itzhaki RF, "Corroboration of a major role for herpes simplex virus type 1 in Alzheimer’s disease", Front Aging Neurosci, 10, pp.324~ (2018)
- Ayele BA, "HIV-associated neurocognitive disorder and HIV-associated myelopathy in a patient with a preserved CD4, but high viral load-a rarely reported phenomenon : a case report and literature review", BMC Infect Dis, 20, pp.574~ (2020)
- Nayeri Chegeni T, "Is Toxoplasma gondii a potential risk factor for Alzheimer’s disease? : a systematic review and meta-analysis", Microb Pathog, 137, pp.103751~ (2019)
- Alonso R, "Identification of fungal species in brain tissue from Alzheimer’s disease by next-generation sequencing", J Alzheimers Dis, 58, pp.55~67 (2017)
- Lovheim H, "Interaction between cytomegalovirus and herpes simplex virus type 1 associated with the risk of Alzheimer’s disease development", J Alzheimers Dis, 61, pp.939~945 (2018)
- Cassiani-Miranda CA, "Neurocognitive disorder due to neurosyphilis:a case report", Rev Colomb Psiquiatr (Engl Ed), 49, pp.202~207 (2020)
- Wiwanitkit V, "Dementia and neurocysticercosis", Acta Neurol Taiwan, 23, pp.1~3 (2014)
- Gradus JL, "Stress disorders and dementia in the Danish population", Am J Epidemiol, 188, pp.493~499 (2019)
- Sindi S, "Midlife work-related stress increases dementia risk in later life : the CAIDE 30-year study", J Gerontol B Psychol Sci Soc Sci, 72, pp.1044~1053 (2017)
- Rafferty LA, "Dementia, post-traumatic stress disorder and major depressive disorder : a review of the mental health risk factors for dementia in the military veteran population", Psychol Med, 48, pp.1400~1409 (2018)
- "Coping with stress at work" (2020)[URL]
- VanItallie TB, "Traumatic brain injury(TBI)in collision sports : possible mechanisms of transformation into chronic traumatic encephalopathy(CTE)", Metabolism, 100S, pp.153943~ (2019)
- Mendez MF, "What is the relationship of traumatic brain injury to dementia?", J Alzheimers Dis, 57, pp.667~681 (2017)
- Sutin AR, "Loneliness and risk of dementia", J Gerontol B Psychol Sci Soc Sci, 75, pp.1414~1422 (2020)
- Sundstrom A, "Loneliness increases the risk of all-cause dementia and Alzheimer’s disease", J Gerontol B Psychol Sci Soc Sci, 75, pp.919~926 (2020)
- Kuiper JS, "Social relationships and risk of dementia : a systematic review and meta-analysis of longitudinal cohort studies", Ageing Res Rev, 22, pp.39~57 (2015)
- Ayenigbara IO, "COVID-19 : measures to protect older adults from SARS-CoV-2 infection", Geriatr Care, 6, pp.9045~ (2020)
- Kuring JK, "Risk of dementia in persons who have previously experienced clinically-significant depression, anxiety, or PTSD : a systematic review and meta-analysis", J Affect Disord, 274, pp.247~261 (2020)
- Lenoir H, "Depression history, depressive symptoms, and incident dementia : the 3C Study", J Alzheimers Dis, 26, pp.27~38 (2011)
- Gutzmann H, "Depression associated with dementia", Z Gerontol Geriatr, 48, pp.305~311 (2015)
- Mirza SS, "10-year trajectories of depressive symptoms and risk of dementia : a population-based study", Lancet Psychiatry, 3, pp.628~635 (2016)
- Hou Z, "Association of depressive symptoms with decline of cognitive function-Rugao longevity and ageing study", Neurol Sci, 41, pp.1873~1879 (2020)
- Wu KY, "Beta-amyloid deposition and cognitive function in patients with major depressive disorder with different subtypes of mild cognitive impairment : (18)F-florbetapir(AV-45", Amyvid)PET study, 2016, pp.43, 1067~1076
- Wu KY, "Increased brain amyloid deposition in patients with a lifetime history of major depression : evidenced on 18F-florbetapir(AV-45", Amyvid)positron emission tomography, 2014, pp.41, 714~722
- Matyas N, "Continuing education for the prevention of mild cognitive impairment and Alzheimer’s-type dementia : a systematic review and overview of systematic reviews", BMJ Open, 9, pp.e027719~ (2019)
- Foverskov E, "Education and adolescent cognitive ability as predictors of dementia in a cohort of Danish men", PLoS One, 15, pp.e0235781~ (2020)
- Ayenigbara IO, "COVID-19(SARS-CoV-2)pandemic : fears, facts and preventive measures", Germs, 10, pp.218~228 (2020)
- Regier NG, "Characteristics of activities for persons with dementia at the mild, moderate, and severe stages", Gerontologist, 57, pp.987~997 (2017)
- Sarkamo T, "Cognitive, emotional, and social benefits of regular musical activities in early dementia : randomized controlled study", Gerontologist, 54, pp.634~650 (2014)
- Tipton PW, "Prevention of late‑life dementia : what works and what does not", Pol Arch Intern Med, 128, pp.310~316 (2018)
