후기발병 양측성 의미변이원발진행실어증 환자에서 보인 비대칭 아밀로이드 국소침착 소견의 해석 및 진단 접근
Decision-making Approach in Late-onset Bilateral Semantic Variant Primary Progressive Aphasia with Coexisting Asymmetric Regional Amyloid Deposition
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Semantic variant primary progressive aphasia (svPPA), a well-known subtype of the frontotemporal dementia often shows peculiar clinical features and structural neuroimage findings. To strengthen the accuracy of a clinical diagnosis, amyloid positron emission tomography-computed tomography (PET-CT) might be helpful. However, in patients with late-onset svPPA, an admixture of the various neuropathology would interfere with diagnostic approach. Herein, we report a case of late-onset bilateral svPPA showing a regional amyloid deposition on PET-CT scan.
Abstract
Semantic variant primary progressive aphasia (svPPA), a well-known subtype of the frontotemporal dementia often shows peculiar clinical features and structural neuroimage findings. To strengthen the accuracy of a clinical diagnosis, amyloid positron emission tomography-computed tomography (PET-CT) might be helpful. However, in patients with late-onset svPPA, an admixture of the various neuropathology would interfere with diagnostic approach. Herein, we report a case of late-onset bilateral svPPA showing a regional amyloid deposition on PET-CT scan.
참고문헌 (10)
- Kertesz A, "What is semantic dementia? : a cohort study of diagnostic features and clinical boundaries", Arch Neurol, 67, pp.483~489 (2010)
- Rohrer JD, "Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration", Brain, 134, pp.2565~2581 (2011)
- Santos-Santos MA, "Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia", JAMA Neurol, 75, pp.342~352 (2018)
- Gorno-Tempini ML, "Classification of primary progressive aphasia and its variants", Neurology, 76, pp.1006~1014 (2011)
- Migliaccio R, "The Brain Network of Naming : A Lesson from Primary Progressive Aphasia", PLoS One, 11, pp.e0148707~ (2016)
- 전병선, "전두측두엽 치매", 생물정신의학, 23(3), pp.69~79 (2016), 대한생물정신의학회
- Mendez MF, "Clinical Features of Late-onset Semantic Dementia", Cogn Behav Neurol, 33, pp.122~128 (2020)
- Reilly J, "Anomia as a marker of distinct semantic memory impairments in Alzheimer’s disease and semantic dementia", Neuropsychology, 25, pp.413~426 (2011)
- Kim H, "Naming deficits in patients with dementia of the Alzheimer type : error analysis of Korean version-Boston Naming Test", J Korean Neurol Assoc, 15, pp.1012~1021 (1997)
- Huey ED, "A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia", Neurology, 66, pp.17~22 (2006)
