수돗물 불소화와 노령 인구의 고관절 골절에 대한 생태학적 연구
Effects of Long-term Fluoride in Drinking Water on Risks of Hip Fracture of the Elderly: An Ecologic Study Based on Database of Hospitalization Episodes
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Objectives : Fluoridation of drinking water is known to decrease dental caries, particularly in children. However, the effects of fluoridated water on bone over several decades are still in controversy. To assess the risk of hip fracture related to water fluoridation, we evaluated the hip fracture-related hospitalizations of the elderly between a fluoridated city and non-fluoridated cities in Korea. Methods : Cheongju as a fluoridated area and Chungju, Chuncheon, Suwon, Wonju as non-fluoridated areas were chosen for the study. We established a database of hip fracture hospitalization episode based on the claims data submitted to the Health Insurance Review Agency from January 1995 to December 2002. The hip fracture hospitalization episodes that satisfied the conditions were those that occurred in patients over 65 years old, the injuries had a hip fracture code (ICD-9 820, ICD-10 S72) and the patients were hospitalized for at least 7days. A total of 80,558 cases of hip fracture hospitalization episodes were analyzed. Results : The admission rates for hip fracture increased with the age of the men and women in both a fluoridated city and the non-fluoridated cities (p<0.01). The relative risk of hip fracture increased significantly both for men and women as their age increased. However, any difference in the hip fracture admission rates was not consistently observed between the fluoridated city and the nonfluoridated cities. Conclusions : We cannot conclude that fluoridation of drinking water increases the risk of hip fracture in the elderly.
Abstract
Objectives : Fluoridation of drinking water is known to decrease dental caries, particularly in children. However, the effects of fluoridated water on bone over several decades are still in controversy. To assess the risk of hip fracture related to water fluoridation, we evaluated the hip fracture-related hospitalizations of the elderly between a fluoridated city and non-fluoridated cities in Korea. Methods : Cheongju as a fluoridated area and Chungju, Chuncheon, Suwon, Wonju as non-fluoridated areas were chosen for the study. We established a database of hip fracture hospitalization episode based on the claims data submitted to the Health Insurance Review Agency from January 1995 to December 2002. The hip fracture hospitalization episodes that satisfied the conditions were those that occurred in patients over 65 years old, the injuries had a hip fracture code (ICD-9 820, ICD-10 S72) and the patients were hospitalized for at least 7days. A total of 80,558 cases of hip fracture hospitalization episodes were analyzed. Results : The admission rates for hip fracture increased with the age of the men and women in both a fluoridated city and the non-fluoridated cities (p<0.01). The relative risk of hip fracture increased significantly both for men and women as their age increased. However, any difference in the hip fracture admission rates was not consistently observed between the fluoridated city and the nonfluoridated cities. Conclusions : We cannot conclude that fluoridation of drinking water increases the risk of hip fracture in the elderly.
참고문헌 (34)
- Raheb, J., "Water fluoridation, bone density and hip fractures: A review of recent literature", Community Dent Oral Epidemiol, 23(5), pp.309~316 (1995)
- 김갑수, "수돗물 불소화사업 찬반논쟁에 따른고찰", 서울도시연구, 5(1), pp.105~118 (2004), 서울시정개발연구원
- "Review on Water Fluoridation"[URL]
- Center for Disease Control & Prevention, "Achievements in public health, 1900-1999: Fluoridation of drinking water to prevent dental caries", M.M.W.R, 48(41), pp.933~940 (1999)
- Petersen, P.E., "Effective use of fluorides for the prevention of dental caries in the 21st century: The WHO approach", Community Dent Oral Epidemiol, 32(5), pp.319~321 (2004)
- Cho, S.H., "Scientific Review on the Health Effect of Community Water Fluoridation Program" (1999), Korean Medical Association
- National Research Council, "Health Effects of Ingested Fluoride" (1993), National Academy Press
- Report of the Expert Panel for Water Fluoridation Review, Appointed by Standing Committee on Operations and Environment, "City of Calgary and Calgary Regional Health Authority", City of Calgary and Calgary Regional Health Authority, ~ (1998)
- Ahokas, J., "Review of Water Fluoridation and Fluoride Intake from Discretionary Fluoride Supplements: Review for NHMRC" (1999), National Health and Medical Research Council
- McDonagh, M.S., "Systemic review of water fluoridation", B.M.J, 321(7265), pp.855~859 (2000)
- Jacobsen, S.J., "The association between water fluoridation and hip fracture among white women and men aged 65 years and older: A national ecologic study", Ann Epidemiol, 2(5), pp.617~626 (1992)
- Suarez-Almazor, M.E., "The fluoridation of drinking water and hip fracture hospitalization rates in two Canadian communities", Am J Public Health, 83(5), pp.689~693 (1993)
- Phipps, K.R., "Community water fluoridation, bone mineral density, and fractures: Prospective study of effects in older women", BMJ, 321(7265), pp.860~864 (2000)
- Li, Y., "Effect of long-term exposure to fluoride in drinking water on risks of bone fractures", J Bone Miner Res, 16(5), pp.932~939 (2001)
- Hornbrook, M.C., "Health care episodes: Definition, measurement and use", Med Care Rev, 42(2), pp.163~218 (1985)
- Korea Water Resources Corporation, "Water fluoridation 2005" (2006), Korea Water Resources Corporation
- Korea National Statistical Office, "Population Census 2005" (2006), Korea National Statistical Office
- Schneider, E.L., "The aging of America: Impact on health care costs", JAMA, 263(17), pp.2335~2340 (1990)
- 이승미, "여성 노인에서 출산력과 고관절 골절 발생간의 관련성 : 코호트 연구", 예방의학회지, 35(4), pp.6~312 (2002), 대한예방의학회
- Zingmoid, D.S., "International hip fracture incidence in California Hispanics, 1983 to 2000", Osteoporos Int, 15(8), pp.603~610 (2004)
- Kelsey, J.L., "Risk factors for hip fracture", N Engl J Med, 316(7), pp.404~406 (1987)
- 윤경은, "노인 인구에서 육체적 활동과 고관절 골절 발생간의 관련성 : 코호트 연구", 예방의학회지, 35(4), pp.11~358 (2002), 대한예방의학회
- Hiller, S, "Water fluoridation and osteoporotic fracture", Community Dent Health, 13(2), pp.63~68 (1996)
- Danielson, C., "Hip fractures and fluoridation in UtahÙs elderly population", JAMA, 268(6), pp.746~748 (1992)
- Kurttio, P., "Exposure to natural fluoride in well water and hip fracture: A cohort analysis in Finland", Am J Epidemiol, 150(8), pp.817~824 (1999)
- Demos, L.L., "Water fluoridation, osteoporosis, fracture: Recent developments", Aust Dent J, 46(2), pp.80~87 (2001)
- Hillier, S., "Fluoride in drinking water and risk of hip fracture in the UK: A case-control study", Lancet, 355(9200), pp.265~269 (2000)
- Lehmann, R., "Drinking water fluoridation: Bone mineral density and hip fracture incidence", Bone, 22(3), pp.273~278 (1998)
- Kim, J.Y., "Using national health insurance data to vitalize the evidence-based health care: The current status and tasks", Workshop for activating medical research using national health insurance data, pp.1~33 (2007), Seoul National University Hospital
- Kim, J.Y., "Changes of Ambulatory Care Service Consumption after the Separation of Prescribing and Dispensing: Analysis with the Episode of Care and Continuity of Care" (2003), Seoul National Univ
- Kim, J., "The weather watch", warning system for stroke and asthma in South Korea, 2008, pp.18(2), 117~127
- Korean Centers for Disease Control, "Development of Strategy and Action Plans for Major Chronic Diseases Prevention and Control" (2004), Ministry of Health and Welfare
- Kim, J.Y., "Construction of National Surveillance System for Cardiovascular & Cerebrovascular Diseases" (2006), Health Insurance Review and Assessment Service
- Allolio, B., "Drinking water fluoridation and bone", Exp Clin Endocrinol Diabetes, 107(1), pp.12~20 (1999)