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두피관리에 사용할 수 있는 효과적인 천연 화장품소재의 탐색

A Screening of Effective Natural Cosmetical Materials for Scalp Care

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초록

Scalp care and scaling are used for prevention of hair damage and alopecia. For the screening of scalp scaling natural materials, shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens were analyzed general ingredient and were proofed cell viability of skin fibroblasts and brain cells and patch test for safety test. Antioxidative (DPPH, SO)effect and antibacterial activity were observed for efficacy, and usability of prepared toner with natural materials. As a result, shiitake mushroom had 14.00%, buckwheat with 5.52%, soybean with 41.51%, and cypress with 24.27% of crude protein, and seaweed fulvescens had 33.67% of crude ash in the general ingredient analysis. In safety evaluation, 50% of cell viability from 5 natural materials extracts was shown in 91~152 μL/mL, and blister (-), redness (-), allergic reaction (-) were not observed after 48 hours closed patch test. When DPPH and SO scavenging were compared with the positive control substance BHT 0.1 mg/mL, shiitake mushroom was 25 μL/mL and 50 μL/mL, buckwheat was 50 μL/mL and 25 μL/mL, soybean was 25~50 μL/mL and 50 μL/mL, cypress was ≤25 μL/mL and ≥50 μL/mL, seaweed fulvescens was 25 μL/mL and 50 μL/mL. Supeiror antioxidative activities from shiitake mushroom and buckwheat extracts were observed. Cypress extracts were showed good antimicrobial activities against S. aureus and S. epidermidis strains with concentration of 150 μL/mL. For the usability evaluation, there were positive responses with ‘good’ and ‘average’ on 5 questions. In conclusion, it was suggested that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens can be used as materials of cosmetics with high safety, usability, and efficiency.

Abstract

Scalp care and scaling are used for prevention of hair damage and alopecia. For the screening of scalp scaling natural materials, shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens were analyzed general ingredient and were proofed cell viability of skin fibroblasts and brain cells and patch test for safety test. Antioxidative (DPPH, SO)effect and antibacterial activity were observed for efficacy, and usability of prepared toner with natural materials. As a result, shiitake mushroom had 14.00%, buckwheat with 5.52%, soybean with 41.51%, and cypress with 24.27% of crude protein, and seaweed fulvescens had 33.67% of crude ash in the general ingredient analysis. In safety evaluation, 50% of cell viability from 5 natural materials extracts was shown in 91~152 μL/mL, and blister (-), redness (-), allergic reaction (-) were not observed after 48 hours closed patch test. When DPPH and SO scavenging were compared with the positive control substance BHT 0.1 mg/mL, shiitake mushroom was 25 μL/mL and 50 μL/mL, buckwheat was 50 μL/mL and 25 μL/mL, soybean was 25~50 μL/mL and 50 μL/mL, cypress was ≤25 μL/mL and ≥50 μL/mL, seaweed fulvescens was 25 μL/mL and 50 μL/mL. Supeiror antioxidative activities from shiitake mushroom and buckwheat extracts were observed. Cypress extracts were showed good antimicrobial activities against S. aureus and S. epidermidis strains with concentration of 150 μL/mL. For the usability evaluation, there were positive responses with ‘good’ and ‘average’ on 5 questions. In conclusion, it was suggested that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens can be used as materials of cosmetics with high safety, usability, and efficiency.

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