Severe lupin bean intoxication: an anticholinergic toxidrome
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Lupin beans are the yellow legume seeds of the genus Lupinus. They are traditionally eaten as a pickled snack in many countries. Bitter lupin beans have a high amount of alkaloids called lupanine. Because the alkaloid is responsible for anticholinergic toxidrome, the beans should pass a debittering process before consumption. Only few pediatric cases of lupin bean intoxication were reported. We present a 12-year-old boy who visited the emergency department for the unexpected onset of anticholinergic toxidrome.
Abstract
Lupin beans are the yellow legume seeds of the genus Lupinus. They are traditionally eaten as a pickled snack in many countries. Bitter lupin beans have a high amount of alkaloids called lupanine. Because the alkaloid is responsible for anticholinergic toxidrome, the beans should pass a debittering process before consumption. Only few pediatric cases of lupin bean intoxication were reported. We present a 12-year-old boy who visited the emergency department for the unexpected onset of anticholinergic toxidrome.
참고문헌 (14)
- Pingault NM, "Two cases of anticholinergic syndrome associated with consumption of bitter lupin flour", Med J Aust, 191, pp.173~174 (2009)
- Di Grande A, "Anticholinergic toxicity associated with lupine seed ingestion : case report", Eur J Emerg Med, 11, pp.119~120 (2004)
- Pothier J, "A comparative study of the effects of sparteine, lupanine and lupin extract on the central nervous system of the mouse", J Pharm Pharmacol, 50, pp.949~954 (1998)
- Daverio M, "Bitter lupine beans ingestion in a child : a disregarded cause of acute anticholinergic toxicity", Eur J Pediatr, 173, pp.1549~1551 (2014)
- Hall RS, "Australian sweet lupin flour addition reduces the glycaemic index of a white bread breakfast without affecting palatability in healthy human volunteers", Asia Pac J Clin Nutr, 14, pp.91~97 (2005)
- Lee YP, "Lupin-enriched bread increases satiety and reduces energy intake acutely", Am J Clin Nutr, 84, pp.975~980 (2006)
- Díez-Láiz R, "Evaluation of the association metformin : Plantago ovata husk in diabetic rabbits", J Diabetes Res, 2015, pp.167526~ (2015)
- Lupin alkaloids in food: a toxicological review and risk assessment, "Australia New Zealand Food Authority (ANZFA)", ANZFA, ~, pp.Technical report series no. 3 (2013)
- Yovo K, "Comparative pharmacological study of sparteine and its ketonic derivative lupanine from seeds of Lupinus albus", Planta Med, 50, pp.420~424 (1984)
- Risk assessment of the occurrence of alkaloids in lupin seeds, "German Federal Institute for Risk Assessment (BfR)", BfR, ~, pp.BfR Opinion No 003 (2017), 2017
- Lowen RJ, "Lupin bean toxicity", Med J Aust, 162, pp.256~257 (1995)
- Luque Marquez R, "Acute poisoning by lupine seed debittering water", Vet Hum Toxicol, 33, pp.265~267 (1991)
- Hefle SL, "Adverse reaction to lupine-fortified pasta", J Allergy Clin Immunol, 94(2 Pt 1), pp.167~172 (1994)
- Tsiodras S, "Anticholinergic toxicity associated with lupine seeds as a home remedy for diabetes mellitus", Ann Emerg Med, 33, pp.715~717 (1999)