의식 변화와 구토를 주소로 내원한 Grayanotoxin Intoxication 1예
A Case of Grayanotoxin Intoxication Presenting with Mental Changes and Vomiting
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Rhododendron species is one of the largest and most diverse genera in the plant kingdom, comprising over 800 species and existing all over the globe. Grayanotoxin intoxication is caused by ingestion of honey and flowers. Grayanotoxin exists in honey, flowers, pollen, and nectar of the Rhododendron species. Grayanotoxin-intoxicated patients may present with nausea, vomiting, dizziness, weakness, hypotension, bradycardia, and syncope for several hours. We report a case of grayanotoxin intoxication associated with mental changes. A 9-year-old male presented with impaired consciousness and delirium 26 hours after eating about 10 rhododendron sclippenbachii flowers. A brain MRI and EEG were normal. Parenteral fluids were administered and these symptoms resolved completely in 17 hours.
Abstract
Rhododendron species is one of the largest and most diverse genera in the plant kingdom, comprising over 800 species and existing all over the globe. Grayanotoxin intoxication is caused by ingestion of honey and flowers. Grayanotoxin exists in honey, flowers, pollen, and nectar of the Rhododendron species. Grayanotoxin-intoxicated patients may present with nausea, vomiting, dizziness, weakness, hypotension, bradycardia, and syncope for several hours. We report a case of grayanotoxin intoxication associated with mental changes. A 9-year-old male presented with impaired consciousness and delirium 26 hours after eating about 10 rhododendron sclippenbachii flowers. A brain MRI and EEG were normal. Parenteral fluids were administered and these symptoms resolved completely in 17 hours.
참고문헌 (12)
- Choi YJ, "Korean folk plants. 1st ed" (1992), Academy Publishing
- Kim AJ, "Grayanotoxin intoxication. 3 case reports", J Korean Soc Emerg Med, 11, pp.372~377 (2000)
- Oh HL, "Two cases of honey poisoning with syncope", J Korean Soc Med, 59, pp.208~212 (2000)
- 손창환, "석청(Mad-honey)복용 후 발생한 심혈관계 중독 증상 환자 3례", 대한응급의학회지, 16(2), pp.322~325 (2005), 대한응급의학회
- 동아, "원색대백과사전. 1st ed", pp.26~116 (1982), 동아출판사
- Gunduz A, "Mad honey poisoning-related asystole", Emerg Med J, 24, pp.592~593 (2007)
- Narahashi T, "Mechanism of nerve membrane depolarization caused by grayanotoxin I", J Physiol, 242, pp.471~487 (1974)
- 8)Seyama I, "Is the site of action of grayanotoxin the sodium channel gating of squid axon?", Jpn J Physiol, 35, pp.401~410 (1985)
- Nakao M, "Effect of alpha-dihydro-grayanotoxin-II on the electrical activity of the rabbit sino-atrial node", J Physiol, 357, pp.79~91 (1984)
- Ozhan H, "Cardiac emergencies caused by honey ingestion: a single centre experience", Emerg Med J, 21, pp.742~744 (2004)
- Haddad L, "Clinical management of poisoning and drug overuse. 3rd ed", Saunders Co, 26, pp.376~384 (1998)
- Onat FY, "Mad honey poisoning in man and rat", Rev Environ Health, 9, pp.3~9 (1991)