본문 바로가기
KERD
논문KCI 등재후보

Effects of a 4-Week Vitamin B6·B9·B12 Supplementation on the Muscle Recovery and Muscular Function Induced by Acute Eccentric EXERCISE

2

조회

0

다운로드

2

인용

0

참고문헌

키워드

초록

We examined the effect of a 4-week vitamin B6·B9·B12 supplementation on the muscle recovery and muscular function induced by acute eccentric exercise. Twenty-nine subjects were volunteered for this study, and they were randomly assigned to either vitamin B6·B9·B12 supplementation group(n=14) or placebo group(n=15). Body composition was measured prior to testing. The vitamin B group was given two tablets of vitamin B6·B9·B12 supplement per day from 4 weeks before eccentric exercise until 72 hours after eccentric exercise, whereas the control group was given two placebo tablets. All subjects performed eccentric exercise using Biodex isokinetic machine after treatment period. They performed a total of 4 sets of eccentric exercise with 12 repetitions per set using their non-dominant arm. Blood samples were taken at pre-exercise, immediately after exercise, and at 6, 24, 48, and 72 hour post-exercise. Maximum isometric force(MIF) and range of motion(ROM) were obtained before and immediately after exercise and at 2, 6, 24, 48, and 72 hour post-exercise. Independent t-tests were conducted to analyze differences between groups in physical characteristics and total amount of work of eccentric exercise. Lactate dehydrogenase(LDH) concentration, MIF, and ROM were analyzed using 2-way repeated measure ANOVA. A main effect for test session and group effect were significant in LDH concentration(p<.05). A main effect for test session for MIF(p<.05) and ROM(p<.05) was significant. In both groups, LDH concentration significantly increased immediately after exercise and at 48, and 72 hour post-exercise compared to pre-exercise(p<.05). LDH concentration of vitamin B group was significantly higher than control group, independent of test session(p<.05). MIF and ROM significantly decreased from immediately after exercise to 48 hours after exercise, and 72 hours post-exercise, respectively, in both groups compared to pre-exercise(p<.05). In conclusion, the results of this study suggest that at least 4-week supplementation of vitamin B6·B9·B12 may not have a positive effect on the recovery of muscle damage and function induced by eccentric exercise.

Abstract

We examined the effect of a 4-week vitamin B6·B9·B12 supplementation on the muscle recovery and muscular function induced by acute eccentric exercise. Twenty-nine subjects were volunteered for this study, and they were randomly assigned to either vitamin B6·B9·B12 supplementation group(n=14) or placebo group(n=15). Body composition was measured prior to testing. The vitamin B group was given two tablets of vitamin B6·B9·B12 supplement per day from 4 weeks before eccentric exercise until 72 hours after eccentric exercise, whereas the control group was given two placebo tablets. All subjects performed eccentric exercise using Biodex isokinetic machine after treatment period. They performed a total of 4 sets of eccentric exercise with 12 repetitions per set using their non-dominant arm. Blood samples were taken at pre-exercise, immediately after exercise, and at 6, 24, 48, and 72 hour post-exercise. Maximum isometric force(MIF) and range of motion(ROM) were obtained before and immediately after exercise and at 2, 6, 24, 48, and 72 hour post-exercise. Independent t-tests were conducted to analyze differences between groups in physical characteristics and total amount of work of eccentric exercise. Lactate dehydrogenase(LDH) concentration, MIF, and ROM were analyzed using 2-way repeated measure ANOVA. A main effect for test session and group effect were significant in LDH concentration(p<.05). A main effect for test session for MIF(p<.05) and ROM(p<.05) was significant. In both groups, LDH concentration significantly increased immediately after exercise and at 48, and 72 hour post-exercise compared to pre-exercise(p<.05). LDH concentration of vitamin B group was significantly higher than control group, independent of test session(p<.05). MIF and ROM significantly decreased from immediately after exercise to 48 hours after exercise, and 72 hours post-exercise, respectively, in both groups compared to pre-exercise(p<.05). In conclusion, the results of this study suggest that at least 4-week supplementation of vitamin B6·B9·B12 may not have a positive effect on the recovery of muscle damage and function induced by eccentric exercise.

참고문헌 (36)

  1. Sousa M, "Dietary Strategies to Recover from Exercise-induced Muscle Damage", International Journal of Food Sciences and Nutrition, 65, pp.151~163 (2014)
  2. Weerapong P, "Preven-tative Strategies for Exercise-induced Muscle Damage", Critical Reviews in Physical and Re-habilitation Medicine, 16(2), pp.133~150 (2004)
  3. Mackey AL, "Skeletal Muscle Col-lagen Content in Humans after High-force Eccentric Contractions", Journal of Applied Physiology, 97, pp.197~203 (2004)
  4. Betts JA, "Short-term Recovery from Prolonged Exercise: Exploring the Po-tential for Protein Ingestion to Accentuate the Benefits of Carbohydrate Supplements", Sports Medicine, 40, pp.941~959 (2010)
  5. Cleak MJ, "Delayed Onset Muscle Soreness: Mechanisms and Management", Journal of Sports Sciences, 10(4), pp.325~341 (1992)
  6. Howatson G, "The Pre-vention and Treatment of Exercise-induced Muscle Damage", Sports Medicine, 38(6), pp.483~503 (2008)
  7. Reilly T, "The Use of Recovery Methods Post-exercise", Journal of Sports Sci-ences, 23(6), pp.619~627 (2005)
  8. Paoloni JA, "Non-steroidal Anti-inflammatory Drugs in Sports Medicine: Guidelines for Practical but Sensible Use", British Journal of Sports Medicine, 43(11), pp.863~865 (2009)
  9. Pizza FX, "Anti-inflammatory Doses of Ibuprofen: Effect on Neutrophils and Ex-ercise-induced Muscle Injury", International Journal of Sports Medicine, 20(2), pp.98~102 (1999)
  10. Rainsford KD, "Profile and Mechanisms of Gastrointestinal and Other Side Effects of Nonsteroidal Anti-inflammatory Drugs (NSAIDs)", The American Journal of Medicine, 107(6A), pp.27S~35S (1999)
  11. Evans WJ, "Vitamin E, Vitamin C, and Exer-cise", The American Journal of Clinical Nutri-tion, 72, pp.647S~652S (2000)
  12. Carr A, "Does Vitamin C Act as a Pro-oxidant under Physiological Conditions?", FASEB Journal, 13, pp.1007~1024 (1999)
  13. McGinley C, "Does Antioxidant Vitamin Supplementation Pro-tect against Muscle Damage?", Sports Medi-cine, 39, pp.1011~1032 (2009)
  14. Thompson D, "Prolonged Vitamin C Supplemen-tation and Recovery from Demanding Exer-cise", International Journal of Sport Nutrition and Exercise Metabolism, 11(4), pp.466~481 (2001)
  15. Sacheck JM, "Effect of Vita-min E and Eccentric Exercise on Selected Bi-omarkers of Oxidative Stress in Young and Elderly Men", Free Radical Biology & Medi-cine, 34, pp.1575~1588 (2003)
  16. Shafat A, "Effects of Dietary Supplementation with Vitamins C and E on Muscle Function during and after Eccentric Contractions in Humans.", European Journal of Applied Physiology, 93(1-2), pp.196~202 (2004)
  17. Bojanić V, "Hydrosoluble Vitamins and Sport", Acta Medica Medianae, 50(2), pp.68~75 (2011)
  18. Manore MM, "Vitamin B6 and Exercise", In-ternational Journal of Sport Nutrition, 4, pp.89~103 (1994)
  19. Depeint F, "Mitochondrial Function and Toxicity: Role of B Vitamins on the One-carbon Transfer Pathways", Chemico-biologi-cal Interactions, 163(1-2), pp.113~132 (2006)
  20. Varela-Moreiras G, "Cobalamin, Folic Acid, and Homocyste-ine", Nutrition Reviews, (Suppl 1), pp.S69~S72 (2009)
  21. Brancaccio P, "Serum Enzyme Monitoring in Sports Medicine", Clinics in Sports Medicine, 27(1), pp.1~18 (2008)
  22. Childs A, "Supplementation with Vitamin C and N-acetyl-cysteine In-creases Oxidative Stress in Humans after an Acute Muscle Injury Induced by Eccentric Ex-ercise", Free Radical Biology and Medicine, 31(6), pp.745~753 (2001)
  23. Braakhuis AJ, "Ef-fects of Dietary Antioxidants on Training and Performance in Female Runners", European Journal of Sport Science, 14(2), pp.160~168 (2014)
  24. Pingitore A, "Exercise and Oxidative Stress: Potential Effects of An-tioxidant Dietary Strategies in Sports", Nutri-tion, 31(7-8), pp.916~922 (2015)
  25. Bryer SC, "Effect of High Dose Vitamin C Supplementation on Muscle Soreness, Damage, Function, and Oxidative Stress to Eccentric Exercise", International Journal of Sport Nutrition and Exercise Me-tabolism, 16(3), pp.270~280 (2006)
  26. Jing-jing Wan, "Muscle fatigue: general understanding and treatment", Experimental and Molecular Medicine, 49, pp.1~11 (2017), 생화학분자생물학회
  27. Martin V, "Effects of Recovery Modes after Knee Ex-tensor Muscles Eccentric Contractions", Med-icine and Science in Sports and Exercise, 36(11), pp.1907~1915 (2004)
  28. Frontera WR, "Skeletal Muscle: A Brief Review of Structure and Function", Cal-cified Tissue International, 96(3), pp.183~195 (2015)
  29. Ingalls CP, "E-C coupling Fail-ure in Mouse EDL Muscle after in Vivo Ec-centric Contractions", Journal of Applied Physiology, 85(1), pp.58~67 (1998)
  30. Corona BT, "Junctophilin Dam-age Contributes to Early Strength Deficits and EC Coupling Failure after Eccentric Con-tractions", American Journal of Physiology. Cell Physiology, 298(2), pp.C365~C376 (2010)
  31. Hwang SY, "Folic Acid Promotes the Myo-genic Differentiation of C2C12 Murine My-oblasts through the Akt Signaling Pathway", International Journal of Molecular Medicine, 36(4), pp.1073~1080 (2015)
  32. Murayama M, "Changes in Hardness of the Human Elbow Flexor Muscles after Eccentric Exercise", European Journal of Applied Physi-ology, 82(5-6), pp.361~367 (2000)
  33. Theodorou AA, "No Effect of Antioxidant Supplementation on Muscle Performance and Blood Redox Status Adap-tations to Eccentric Training", The American Journal of Clinical Nutrition, 93(6), pp.1373~1383 (2011)
  34. Tiidus PM, "Skeletal Muscle Damage and Re-pair" (2008), Human Kinetics
  35. Fink HH, "Prac-tical Applications in Sports Nutrition" (2006), Jones and Bartlett Publishers
  36. Gropper SS, "Ad-vanced Nutrition and Human Metabolism" (2009), Wadsworth Cengage Learning

관련 논문AI추천

이 간행물의 다른 논문 (3건)