Regular moderate exercise training can alter the urinary excretion of thiamin and riboflavin
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BACKGROUND/OBJECTIVES: Physical exercise promotes energy producing pathways requiring thiamin and riboflavin as a coenzyme. Therefore, this study investigated the effects of regular exercise training on urinary excretion of thiamin and riboflavin. MATERIALS/METHODS: Fifty rats were randomly assigned to one of two groups: non-exercise training (NT, n = 25) and regularexercise training (ET, n = 25) for 5 weeks. The rats performed moderate exercise on a treadmill (0.5-0.8 km/hour) for 30 min/day,5 days/week. Twenty-four hour urine samples were collected at the end of the 0 week, 3rd week, and 5th week of trainingand thiamin and riboflavin were analyzed. RESULTS: No significant differences in thiamin and riboflavin intakes for each week were observed between the NT and ETgroups. Urinary thiamin excretion of each group was the highest at the 5th week compared to the levels at 0 and 3rd week. Urinary thiamin at the 5th week was significantly lower in the ET group than in the NT group. Urinary riboflavin excretionwas increased by training duration, however, no difference was observed between NT and ET for each week. At 0 and 3rdweek, no significant relationships were observed between dietary intake and urinary excretion of thiamin and riboflavin, however,at the 5th week, urinary excretion was significantly increased by dietary intake only in the NT group (P < 0.05). Thiamin excretionof both NT and ET groups was significantly increased with riboflavin excretion at the 5th week (P < 0.01). CONCLUSION: Regular moderate exercise training increased urinary excretion of thiamin. Dietary intakes and urinary excretionsof thiamin and riboflavin showed positive correlation in both the exercise training and non-exercise training groups as theexercise training period went by, while the correlations in the exercise training group were weaker than those in the non-exercisetraining group. Therefore, regular exercise training can alter the urinary excretion of thiamin and riboflavin in rats.
Abstract
BACKGROUND/OBJECTIVES: Physical exercise promotes energy producing pathways requiring thiamin and riboflavin as a coenzyme. Therefore, this study investigated the effects of regular exercise training on urinary excretion of thiamin and riboflavin. MATERIALS/METHODS: Fifty rats were randomly assigned to one of two groups: non-exercise training (NT, n = 25) and regularexercise training (ET, n = 25) for 5 weeks. The rats performed moderate exercise on a treadmill (0.5-0.8 km/hour) for 30 min/day,5 days/week. Twenty-four hour urine samples were collected at the end of the 0 week, 3rd week, and 5th week of trainingand thiamin and riboflavin were analyzed. RESULTS: No significant differences in thiamin and riboflavin intakes for each week were observed between the NT and ETgroups. Urinary thiamin excretion of each group was the highest at the 5th week compared to the levels at 0 and 3rd week. Urinary thiamin at the 5th week was significantly lower in the ET group than in the NT group. Urinary riboflavin excretionwas increased by training duration, however, no difference was observed between NT and ET for each week. At 0 and 3rdweek, no significant relationships were observed between dietary intake and urinary excretion of thiamin and riboflavin, however,at the 5th week, urinary excretion was significantly increased by dietary intake only in the NT group (P < 0.05). Thiamin excretionof both NT and ET groups was significantly increased with riboflavin excretion at the 5th week (P < 0.01). CONCLUSION: Regular moderate exercise training increased urinary excretion of thiamin. Dietary intakes and urinary excretionsof thiamin and riboflavin showed positive correlation in both the exercise training and non-exercise training groups as theexercise training period went by, while the correlations in the exercise training group were weaker than those in the non-exercisetraining group. Therefore, regular exercise training can alter the urinary excretion of thiamin and riboflavin in rats.
참고문헌 (32)
- Williams MH, "Dietary supplements and sports performance:introduction and vitamins", J Int Soc Sports Nutr, 1, pp.1~6 (2004)
- McCormick DB, "Encyclopedia of Human Biology. 2nd ed", pp.847~864 (1997), Academic Press
- Woolf K, "B-vitamins and exercise: does exercise alter requirements?", Int J Sport Nutr Exerc Metab, 16, pp.453~484 (2006)
- Johnson Gubler C., "Handbook of Vitamins: Nutritional, Biochemical, and Clinical Aspects", pp.245~295 (1984), Marcel Dekker
- Al-Tamimi EK, "Sports Nutrition: Vitamins and Trace Elements. 2nd ed", pp.47~60 (2006), CRC Press
- Manore MM, "Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements", Am J Clin Nutr, 72, pp.598S~606S (2000)
- Kreider RB, "ISSN exercise & sport nutrition review: research & recommendations", J Int Soc Sports Nutr, 7, pp.7~ (2010)
- Ravi Kiran T, "Swim exercise training and adaptations in the antioxidant defense system of myocardium of old rats: relationship to swim intensity and duration", Comp Biochem Physiol B Biochem Mol Biol, 137, pp.187~196 (2004)
- Lira FS, "Chronic exercise decreases cytokine production in healthy rat skeletal muscle", Cell Biochem Funct, 27, pp.458~461 (2009)
- Campbell PT, "Effect of exercise on oxidative stress: a 12-month randomized, controlled trial", Med Sci Sports Exerc, 42, pp.1448~1453 (2010)
- 최은영, "The influence of different durations of aerobic exercise on fuel utilization, lactate level and antioxidant defense system in trained rats", Nutrition Research and Practice, 8(1), pp.27~32 (2014), 한국영양학회
- Losa R, "Determination of thiamine and its phosphorylated forms in human plasma, erythrocytes and urine by HPLC and fluorescence detection: a preliminary study on cancer patients", J Pharm Biomed Anal, 37, pp.1025~1029 (2005)
- Gatautis VJ, "Liquid-chromatographic determination of urinary riboflavin", Clin Chem, 27, pp.1672~1675 (1981)
- Zempleni J, "Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans", Am J Clin Nutr, 63, pp.54~66 (1996)
- Horwitt MK, "Interpretations of requirements for thiamin, riboflavin, niacin-tryptophan, and vitamin E plus comments on balance studies and vitamin B-6", Am J Clin Nutr, 44, pp.973~985 (1986)
- Powers HJ, "Current knowledge concerning optimum nutritional status of riboflavin, niacin and pyridoxine", Proc Nutr Soc, 58, pp.435~440 (1999)
- Tasevska N, "Twenty-fourhour urinary thiamine as a biomarker for the assessment of thiamine intake", Eur J Clin Nutr, 62, pp.1139~1147 (2008)
- Fukuwatari T, "Urinary water-soluble vitamins and their metabolite contents as nutritional markers for evaluating vitamin intakes in young Japanese women", J Nutr Sci Vitaminol (Tokyo), 54, pp.223~229 (2008)
- Tsuji T, "Urinary excretion of vitamin B1, B2, B6, niacin, pantothenic acid, folate, and vitamin C correlates with dietary intakes of free-living elderly, female Japanese", Nutr Res, 30, pp.171~178 (2010)
- Fogelholm M, "Micronutrient status in females during a 24-week fitness-type exercise program", Ann Nutr Metab, 36, pp.209~218 (1992)
- 최성근, "The effects of endurance training and thiamine supplementation on anti-fatigue during exercise", Journal of Exercise Nutrition & Biochemistry, 17(4), pp.189~198 (2013), 한국운동영양학회
- 최은영, "Moderate Physical Training Can Increase Muscle Glycogen Levels but Does Not Alter Protein Levels with Exercise in Rats", Nutritional Sciences, 9(2), pp.112~116 (2006), 한국영양학회
- 조윤옥, "The effects of physical training on antioxidative status under exercise-induced oxidative stress", Nutrition Research and Practice, 1(1), pp.14~18 (2007), 한국영양학회
- Masuda H, "A thiamin derivative inhibits oxidation of exogenous glucose at rest, but not during exercise", J Nutr Sci Vitaminol (Tokyo), 56, pp.9~12 (2010)
- Shibata K, "Intra- and inter-individual variations of blood and urinary water-soluble vitamins in Japanese young adults consuming a semi-purified diet for 7 days", J Nutr Sci Vitaminol (Tokyo), 55, pp.459~470 (2009)
- Vallerand AL, "Influence of exercise training on tissue chromium concentrations in the rat", Am J Clin Nutr, 39, pp.402~409 (1984)
- Hunter KE, "Effect of exercise on riboflavin status of rats", J Nutr, 117, pp.298~304 (1987)
- Gollnick PD, "Effect of training on enzyme activity and fiber composition of human skeletal muscle", J Appl Physiol, 34, pp.107~111 (1973)
- Molé PA, "Adaptation of muscle to exercise. Increase in levels of palmityl CoA synthetase, carnitine palmityltransferase, and palmityl CoA dehydrogenase, and in the capacity to oxidize fatty acids", J Clin Invest, 50, pp.2323~2330 (1971)
- Belko AZ, "Effects of aerobic exercise and weight loss on riboflavin requirements of moderately obese, marginally deficient young women", Am J Clin Nutr, 40, pp.553~561 (1984)
- Belko AZ, "Effects of exercise on riboflavin requirements: biological validation in weight reducing women", Am J Clin Nutr, 41, pp.270~277 (1985)
- Sato A, "Dietary thiamin and riboflavin intake and blood thiamin and riboflavin concentrations in college swimmers undergoing intensive training", Int J Sport Nutr Exerc Metab, 21, pp.195~204 (2011)