가정 내 최초 감염된 소아청소년이 가구원에게 코로나바이러스감염증-19를 전파하는 관련 요인
Factors Related to the Transmission of COVID-19 within Households from Pediatric Initial Cases
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: This study aims to identify pediatric COVID-19 transmission the general and epidemiological characteristics within households and deter- mine odds ratios (OR) of transmission based on these characteristics. Methods: This study analyzed all laboratory-confirmed (PCR +) initial pediatric COVID-19 cases aged 0 to 18 years reported in Daegu, Republic of Korea, between February 18, 2020, and December 31, 2021 (n = 1,348). Household transmission was defined as households where at least one secondary case occurs within 1 to 14 days after the pediatric initial case. The study excluded cases that were known as the index case in the household but were identified as a secondary case through epidemiological investigation. Additionally, if the source of infection was unknown, they were excluded, provided at least one family member confirmed positive on the laboratory-contact test, including cases with incomplete epidemiological investigation. Results: 469 cases (34.8%) experienced household transmission. Male, symptomatic and cases with unknown source of infection had higher OR of transmitting COVID-19 to the household compared to the opposite scenarios (Male: OR, 1.36; 95% CI, 1.07-1.74; Symptomatic: OR, 1.93; 95% CI, 1.36-2.73; unknown source of infection: OR, 2.26; 95% CI, 1.59-3.21). Moreover, the age group of 4-6 years had the highest OR of transmitting COVID-19 to household contacts compared to the age group of 13-18 years(OR, 3.59; 95% CI, 2.55-5.05), and the age groups of 7-12 years (OR, 2.62; 95% CI, 1.94-3.53) and 0-3 years (OR, 2.25; 95% CI, 1.22-4.15) also showed higher ORs. However, the OR for the Ct value was 0.98 (95% CI, 0.96-0.99). Conclusions: This study suggests that male, symptomatic and cases with unknown sources in pediatric COVID- 19 patients are more likely to transmit COVID-19 within households. Younger pediatric patients have higher OR for COVID-19 households transmission than older ones. However, the high Ct value indicated a lower likelihood of transmission.
Abstract
Objectives: This study aims to identify pediatric COVID-19 transmission the general and epidemiological characteristics within households and deter- mine odds ratios (OR) of transmission based on these characteristics. Methods: This study analyzed all laboratory-confirmed (PCR +) initial pediatric COVID-19 cases aged 0 to 18 years reported in Daegu, Republic of Korea, between February 18, 2020, and December 31, 2021 (n = 1,348). Household transmission was defined as households where at least one secondary case occurs within 1 to 14 days after the pediatric initial case. The study excluded cases that were known as the index case in the household but were identified as a secondary case through epidemiological investigation. Additionally, if the source of infection was unknown, they were excluded, provided at least one family member confirmed positive on the laboratory-contact test, including cases with incomplete epidemiological investigation. Results: 469 cases (34.8%) experienced household transmission. Male, symptomatic and cases with unknown source of infection had higher OR of transmitting COVID-19 to the household compared to the opposite scenarios (Male: OR, 1.36; 95% CI, 1.07-1.74; Symptomatic: OR, 1.93; 95% CI, 1.36-2.73; unknown source of infection: OR, 2.26; 95% CI, 1.59-3.21). Moreover, the age group of 4-6 years had the highest OR of transmitting COVID-19 to household contacts compared to the age group of 13-18 years(OR, 3.59; 95% CI, 2.55-5.05), and the age groups of 7-12 years (OR, 2.62; 95% CI, 1.94-3.53) and 0-3 years (OR, 2.25; 95% CI, 1.22-4.15) also showed higher ORs. However, the OR for the Ct value was 0.98 (95% CI, 0.96-0.99). Conclusions: This study suggests that male, symptomatic and cases with unknown sources in pediatric COVID- 19 patients are more likely to transmit COVID-19 within households. Younger pediatric patients have higher OR for COVID-19 households transmission than older ones. However, the high Ct value indicated a lower likelihood of transmission.
참고문헌 (32)
- "WHO Director-General’s opening remarks at the media briefing on COVID-19-11 March 2020"[URL]
- "COVID-19, changes in the response to infectious diseases over the past three years" (2023)[URL]
- Daegu Metropolitan Medical Association, "Records of Daegu City Medical Association : 2020 COVID-19 White paper" (2021), Daegu City Medical Association
- Seoul Foundation of Women and Family, "Gender equality living guide:Telecommuting edition" (2021), Seoul Foundation of Women and Family
- Jieun Kim, "Role of children in household transmission of COVID-19", Archives of Disease in Childhood, 106(7), pp.709~711 (2020), BMJ[DOI]
- 곽병옥, "코로나바이러스감염증-19: 소아청소년의 임상 경과가 성인에 비하여 양호한 이유", Pediatric Infection and Vaccine, 28(1), pp.1~6 (2021), 대한소아감염학회[DOI]
- Defi Efendi, "Nursing care recommendation for pediatric COVID-19 patients in the hospital setting: A brief scoping review", PLOS ONE, 17(2), pp.e0263267~ (2022), Public Library of Science (PLoS)[DOI]
- Geraldine Blanchard-Rohner, "Pediatric COVID-19: Immunopathogenesis, Transmission and Prevention", Vaccines, 9(9), pp.1002~ (2021), MDPI AG[DOI]
- Alasdair P S Munro, "Children are not COVID-19 super spreaders: time to go back to school", Archives of Disease in Childhood, 105(7), pp.618~619 (2020), BMJ[DOI]
- 박수은, "코로나바이러스감염증-19의 바이러스(SARS-CoV-2) 특징, 전파 및 임상 양상", Pediatric Infection and Vaccine, 27(1), pp.1~10 (2020), 대한소아감염학회[DOI]
- 김수경, "호흡기 바이러스의 동역학 연구와 감염관리", 의료관련감염관리, 23(1), pp.1~7 (2018), 대한의료관련감염관리학회
- 최수한, "소아청소년 코로나바이러스감염증-19: 역학과 임상 양상", Pediatric Infection and Vaccine, 27(1), pp.11~23 (2020), 대한소아감염학회[DOI]
- Fang F, "Facing the pandemic of 2019 novel coronavirus infections : The pediatric perspectives", Zhonghua Er Ke Za Zhi, 58(2), pp.81~85 (2020)[DOI]
- Feng Fang, "Recommendations for the Diagnosis, Prevention, and Control of Coronavirus Disease-19 in Children—The Chinese Perspectives", Frontiers in Pediatrics, 8 (2020), Frontiers Media SA[DOI]
- Young Joon Park, "Contact Tracing during Coronavirus Disease Outbreak, South Korea, 2020", Emerging Infectious Diseases, 26(10), pp.2465~2468 (2020), Centers for Disease Control and Prevention (CDC)[DOI]
- Lauren A. Paul, "Association of Age and Pediatric Household Transmission of SARS-CoV-2 Infection", JAMA Pediatrics, 175(11), pp.1151~ (2021), American Medical Association (AMA)[DOI]
- Kim YW, "Analysis of COVID-19 confirmed cases and household contacts during the Omicron dominance period (February 1st to 14th, 2022)", Public Health Rep, 15(15), pp.951~955 (2022)
- Vivian Clayton, "Erikson’s Theory of Human Development as it Applies to the Aged: Wisdom as Contradictive Cognition", Human Development, 18(1-2), pp.119~128 (1975), S. Karger AG[DOI]
- Yang SC, "Report on the occurrence of COVID-19 confirmed cases in South Korea for 2 years (January 20, 2020, to January 19, 2022)", Public Health Rep, 15(7), pp.414~426 (2022)
- Nicolás Bronfman, "Gender Differences on Psychosocial Factors Affecting COVID-19 Preventive Behaviors", Sustainability, 13(11), pp.6148~ (2021), MDPI AG[DOI]
- 김선영, "유아의 연령과 성별 및 비만도에 따른 놀이행동에 관한 연구", 한국보육학회지, 7(2), pp.73~89 (2007), 한국보육학회
- 권희경, "아동 성별에 따른 실행기능 관련 변인 연구", 유아교육연구, 41(4), pp.323~343 (2021), 한국유아교육학회[DOI]
- 김상아, "유아의 성별에 따른 놀이성과 의사소통 능력 및 또래놀이 상호작용의 관계", 생태유아교육연구, 20(3), pp.77~99 (2021), 한국생태유아교육학회[DOI]
- 허중연, "코로나바이러스감염병-19 초기 유행의 임상 역학적 특성", 대한내과학회지, 95(2), pp.67~73 (2020), 대한내과학회[DOI]
- M A Chilvers, "Functional analysis of cilia and ciliated epithelial ultrastructure in healthy children and young adults", Thorax, 58(4), pp.333~338 (2003), BMJ[DOI]
- 이상선, "코로나19 대응에 따른 긴급보육 운영: 영아전담 어린이집 사례를 중심으로", 유아교육학논집, 25(5), pp.223~249 (2021), 한국영유아교원교육학회[DOI]
- 배은정, "코로나19로 인한 유아의 일상생활 변화와 어머니의 코로나19 감염에 대한 걱정이 양육스트레스에 미치는영향", 아동학회지, 42(4), pp.445~456 (2021), 한국아동학회
- Bartlett JD, "Resources for supporting children’s emotional well-being during the COVID-19 pandemic", Child Trends, 12(1) (2020)
- 곽태진, "코로나19로 인한 청소년 신체활동 변화와 정신건강 변인의 관계", 한국체육과학회지, 31(5), pp.911~921 (2022), 한국체육과학회[DOI]
- Di Tian, "Ct Values Do Not Predict Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmissibility in College Students", The Journal of Molecular Diagnostics, 23(9), pp.1078~1084 (2021), Elsevier BV[DOI]
- The Korean Society for Laboratory Medicine, "Guidelines for the laboratory diagnosis of COVID-19 in Korea" (2021), The Korean Society for Laboratory Medicine,Korea Disease Control and Prevention Agency
- Kim Jong-yeon, "Epidemiologic Characteristics of a COVID-19 Outbreak Caused by Religious Activities in Daegu, Korea", Epidemiology and Health, 43, pp.1~9 (2021), 한국역학회[DOI]