Characterization of dental phenotypes and treatment modalities in Korean patients with Parry–Romberg syndrome
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Objective: To investigate the dental phenotypes and treatment modalities (Tx- Mod) in Korean patients with Parry–Romberg syndrome (PRS) using longitudinal data. Methods: The samples consisted of 10 PRS patients, who were treated and/or followed-up at Seoul National University Dental Hospital between 1998 and 2019. Using a novel PRS severity index based on the numbers of the atrophy-involved area and asymmetry-involved item, we classified them into mild (n = 3), moderate (n = 2), and severe (n = 5). Dental phenotypes, including congenitally missing tooth (Con-Missing-Tooth), microdontia, tooth with short root (Short-Root), tooth with dilacerated root, and delayed eruption/impacted tooth, were investigated along with Tx-Mod. Results: The side of occurrence of all dental phenotypes showed 100% concordance with the side of PRS involvement. The most two common dental phenotypes were Con-Missing- Tooth and Short-Root (n = 29 and n = 17 in six patients). The sums of the average number of Con-Missing-Tooth and Short-Root increased from mild PRS to moderate PRS and severe PRS cases (1.0, 6.0, and 6.2). In terms of Tx- Mod, growth observation due to mild atrophy, fixed orthodontic treatment, and grafting were used for mild PRS cases. Tx-Mod for moderate PRS cases involved growth observation for surgery due to an early age at the initial visit. For severe PRS cases, diverse Tx-Mod combinations including unilateral functional appliance, fixed orthodontic treatment, growth observation, grafting, and orthognathic surgery were used. Conclusions: The novel PRS severity index may be useful to provide primary data for individualized diagnosis and treatment planning for PRS patients.
Abstract
Objective: To investigate the dental phenotypes and treatment modalities (Tx- Mod) in Korean patients with Parry–Romberg syndrome (PRS) using longitudinal data. Methods: The samples consisted of 10 PRS patients, who were treated and/or followed-up at Seoul National University Dental Hospital between 1998 and 2019. Using a novel PRS severity index based on the numbers of the atrophy-involved area and asymmetry-involved item, we classified them into mild (n = 3), moderate (n = 2), and severe (n = 5). Dental phenotypes, including congenitally missing tooth (Con-Missing-Tooth), microdontia, tooth with short root (Short-Root), tooth with dilacerated root, and delayed eruption/impacted tooth, were investigated along with Tx-Mod. Results: The side of occurrence of all dental phenotypes showed 100% concordance with the side of PRS involvement. The most two common dental phenotypes were Con-Missing- Tooth and Short-Root (n = 29 and n = 17 in six patients). The sums of the average number of Con-Missing-Tooth and Short-Root increased from mild PRS to moderate PRS and severe PRS cases (1.0, 6.0, and 6.2). In terms of Tx- Mod, growth observation due to mild atrophy, fixed orthodontic treatment, and grafting were used for mild PRS cases. Tx-Mod for moderate PRS cases involved growth observation for surgery due to an early age at the initial visit. For severe PRS cases, diverse Tx-Mod combinations including unilateral functional appliance, fixed orthodontic treatment, growth observation, grafting, and orthognathic surgery were used. Conclusions: The novel PRS severity index may be useful to provide primary data for individualized diagnosis and treatment planning for PRS patients.
참고문헌 (21)
- Stone J, "Parry-Romberg syndrome : a global survey of 205 patients using the internet", Neurology, 61, pp.674~676 (2003)
- Pinheiro TP, "Progressive hemifacial atrophy--case report", Med Oral Patol Oral Cir Bucal, 11, pp.E112~E114 (2006)
- Patel H, "Parry-Romberg syndrome : a rare entity", J Maxillofac Oral Surg, 9, pp.247~250 (2010)
- El-Kehdy J, "A review of Parry-Romberg syndrome", J Am Acad Dermatol, 67, pp.769~784 (2012)
- "Parry Romberg syndrome" (2020)[URL]
- Blaszczyk M, "Progressive facial hemiatrophy : central nervous system involvement and relationship with scleroderma en coup de sabre", J Rheumatol, 30, pp.1997~2004 (2003)
- Gonul M, "Parry-Romberg syndrome in association with anti-dsDNA antibodies : a case report", J Eur Acad Dermatol Venereol, 19, pp.740~742 (2005)
- O'Flynn S, "Parry-Romberg syndrome : a report of the dental findings in a child followed up for 9 years", Int J Paediatr Dent, 16, pp.297~301 (2006)
- Tollefson MM, "En coup de sabre morphea and Parry-Romberg syndrome : a retrospective review of 54 patients", J Am Acad Dermatol, 56, pp.257~263 (2007)
- Al-Aizari NA, "Oral manifestations of Parry-Romberg syndrome : a review of literature", Avicenna J Med, 5, pp.25~28 (2015)
- de Vasconcelos Carvalho M, "Association of aesthetic and orthodontic treatment in Parry-Romberg syndrome", J Craniofac Surg, 21, pp.436~439 (2010)
- Hu J, "Combined skeletal and soft tissue reconstruction for severe Parry-Romberg syndrome", J Craniofac Surg, 22, pp.937~941 (2011)
- Foster TD, "The effects of hemifacial atrophy on dental growth", Br Dent J, 146, pp.148~150 (1979)
- Fayad S, "Root resorptions in a patient with hemifacial atrophy", J Endod, 20, pp.299~303 (1994)
- Mazzeo N, "Progressive hemifacial atrophy (Parry-Romberg syndrome). Case report", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 79, pp.30~35 (1995)
- Urban J, "Progressive hemifacial atrophy : ten-year observation of a case", Cutis, 58, pp.165~168 (1996)
- Kurian K, "Facial hemiatrophy--a report of 5 cases", Indian J Dent Res, 14, pp.238~245 (2003)
- Colquhoun AN, "Hemifacial atrophy with bilateral short roots", Br J Oral Maxillofac Surg, 38, pp.533~536 (2000)
- Dixit S, "Scleroderma and dentistry : two case reports", J Med Case Rep, 10, pp.297~ (2016)
- Grippaudo C, "Management of craniofacial development in the Parry-Romberg syndrome : report of two patients", Cleft Palate Craniofac J, 41, pp.95~104 (2004)
- You KH, "Orthopedic and orthodontic treatment of Parry-Romberg syndrome", J Craniofac Surg, 22, pp.970~973 (2011)