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Galactorrhea Probably Related with Switching from Osmotic-release Oral System Methylphenidate (MPH) to Modified-release MPH: An Adolescent Case

Ozalp Ekinci|Nuran Ekinci|Serkan Gunes
대한정신약물학회 (Korean College of Neuropsychopharmacology)|2017.08|Clinical Psychopharmacology and Neuroscience|제15권 제3호|pp. 282-284|DOI https://doi.org/10.9758/cpn.2017.15.3.282

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참고문헌

키워드

MethylphenidateAdolescent.Selective serotonin reuptake inhibitorsGalactorrhea

초록

Galactorrhea, as an adverse effect of psychotropic medications, usually develops due to high dose of antipsychotics. Selective serotonin reuptake inhibitors (SSRIs) have also been reported to be related to galactorrhea. To the best of our knowledge, no previous study reported galactorrhea with methylphenidate (MPH) use. Hereby, we report a case of an adolescent girl who developed galactorrhea after increasing his modifed-release oral MPH to 50 mg/day while under treatment of sertraline and very low dose haloperidol.

Abstract

Galactorrhea, as an adverse effect of psychotropic medications, usually develops due to high dose of antipsychotics. Selective serotonin reuptake inhibitors (SSRIs) have also been reported to be related to galactorrhea. To the best of our knowledge, no previous study reported galactorrhea with methylphenidate (MPH) use. Hereby, we report a case of an adolescent girl who developed galactorrhea after increasing his modifed-release oral MPH to 50 mg/day while under treatment of sertraline and very low dose haloperidol.

참고문헌 (18)

  1. Ensat F, "Unilateral gynecomastia in a prepubertal boy", Eur J Pediatr, 171, pp.197~ (2012)
  2. Coskun M, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", J Clin Psychopharmacol, 34, pp.537~538 (2014)
  3. Almış BH, "Methylphenidate induced gynecomastia in a prepubertal boy: a case report", Anadolu Psikiyatri Derg, 17(Suppl 3), pp.74~76 (2016)
  4. Nebhinani N, "Sertraline-induced galactorrhea: case report and review of cases reported with other SSRIs", Gen Hosp Psychiatry, 35, pp.576.e3~576.e5 (2013)
  5. Windgassen K, "Galactorrhea and hyperprolactinemia in schizophrenic patients on neuroleptics : frequency and etiology", Neuropsychobiology, 33, pp.142~146 (1996)
  6. Seshadri Sekhar Chatterjee, "Emerging Hyperprolactinemic Galactorrhea in Obsessive Compulsive Disorder with a Stable Dose of Fluoxetine", Clinical Psychopharmacology and Neuroscience, 13(3), pp.316~318 (2015), 대한정신약물학회
  7. Bronzo MR, "Galactorrhea induced by sertraline", Am J Psychiatry, 150, pp.1269~1270 (1993)
  8. Lesaca TG, "Sertraline and galactorrhea", J Clin Psychopharmacol, 16, pp.333~334 (1996)
  9. Damsa C, ""Dopamine-dependent" side effects of selective serotonin reuptake inhibitors : a clinical review", J Clin Psychiatry, 65, pp.1064~1068 (2004)
  10. Kitaichi Y, "Sertraline increases extracellular levels not only of serotonin, but also of dopamine in the nucleus accumbens and striatum of rats", Eur J Pharmacol, 647, pp.90~96 (2010)
  11. Coghill D, "Long-acting methylphenidate formulations in the treatment of attention-deficit", hyperactivity disorder : a systematic review of head-to-head studies, 2013, pp.13, 237~
  12. Husain A, "Methylphenidate, neuroleptics and dyskinesia-dystonia", Can J Psychiatry, 25, pp.254~258 (1980)
  13. Peña KS, "Evaluation and treatment of galactorrhea", Am Fam Physician, 63, pp.1763~1770 (2001)
  14. Sulzer D, "Mechanisms of neurotransmitter release by amphetamines : a review", Prog Neurobiol, 75, pp.406~433 (2005)
  15. Ashton AK, "Hyperprolactinemia and galactorrhea induced by serotonin and norepinephrine reuptake inhibiting antidepressants", Am J Psychiatry, 164, pp.1121~1122 (2007)
  16. Hannestad J, "Clinically relevant doses of methylphenidate significantly occupy norepinephrine transporters in humans in vivo", Biol Psychiatry, 68, pp.854~860 (2010)
  17. Volkow ND, "Serotonin and the therapeutic effects of ritalin", Science, 288, pp.11~ (2000)
  18. Daniali S, "Chronic Ritalin administration during adulthood increases serotonin pool in rat medial frontal cortex", Iran Biomed J, 17, pp.134~139 (2013)

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