Manic Symptoms Due to Methylphenidate Use in an Adolescent with Traumatic Brain Injury
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Almost one-fifth of children who sustain a traumatic brain injury (TBI) are under the risk of attention problems after injury. The efficacy and tolerability of methylphenidate (MPH) in children with a history of TBI have not been completely identified. In this case report, MPH-induced manic symptoms in an adolescent with TBI will be summarized. A male patient aged 17 years was admitted with the complaints of attention difficulties on schoolwork and forgetfullness which became evident after TBI. Long-acting MPH was administered with the dose of 18 mg/day for attention problems. After one week, patient presented with the complaints of talking to himself, delusional thoughts, irritability and sleeplessness. This case highlights the fact that therapeutic dose of MPH may cause mania-like symptoms in children with TBI. Close monitarization and slow dose titration are crucial when considering MPH in children with TBI.
Abstract
Almost one-fifth of children who sustain a traumatic brain injury (TBI) are under the risk of attention problems after injury. The efficacy and tolerability of methylphenidate (MPH) in children with a history of TBI have not been completely identified. In this case report, MPH-induced manic symptoms in an adolescent with TBI will be summarized. A male patient aged 17 years was admitted with the complaints of attention difficulties on schoolwork and forgetfullness which became evident after TBI. Long-acting MPH was administered with the dose of 18 mg/day for attention problems. After one week, patient presented with the complaints of talking to himself, delusional thoughts, irritability and sleeplessness. This case highlights the fact that therapeutic dose of MPH may cause mania-like symptoms in children with TBI. Close monitarization and slow dose titration are crucial when considering MPH in children with TBI.
참고문헌 (31)
- Nikles CJ, "Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury--a pilot study", Trials, 15, pp.54~ (2014)
- Catroppa C, "Traumatic brain injury in childhood:rehabilitation considerations", Dev Neurorehabil, 12, pp.53~61 (2009)
- Beauchamp M, "Selective changes in executive functioning ten years after severe childhood traumatic brain injury", Dev Neuropsychol, 36, pp.578~595 (2011)
- Taylor HG, "Traumatic brain injury in young children: postacute effects on cognitive and school readiness skills", J Int Neuropsychol Soc, 14, pp.734~745 (2008)
- Gerring JP, "Premorbid prevalence of ADHD and development of secondary ADHD after closed head injury", J Am Acad Child Adolesc Psychiatry, 37, pp.647~654 (1998)
- 김붕년, "Switching from Methylphenidate-Immediate Release (MPH-IR) to Methylphenidate- OROS (OROS-MPH): A Multi-center, Open-label Study in Korea", Clinical Psychopharmacology and Neuroscience, 9(1), pp.29~35 (2011), 대한정신약물학회
- Lucas AR, "Methylphenidate hallucinosis", JAMA, 217, pp.1079~1081 (1971)
- Ross RG, "Psychotic and manic-like symptoms during stimulant treatment of attention deficit hyperactivity disorder", Am J Psychiatry, 163, pp.1149~1152 (2006)
- Backeljauw B, "Interventions for attention problems after pediatric traumatic brain injury: what is the evidence?", PM R, 6, pp.814~824 (2014)
- Max JE, "Attention deficit hyperactivity disorder in children and adolescents following traumatic brain injury", Dev Neuropsychol, 25, pp.159~177 (2004)
- Wehmeier PM, "Social and emotional impairment in children and adolescents with ADHD and the impact on quality of life", J Adolesc Health, 46, pp.209~217 (2010)
- Williams SE, "Recovery in pediatric brain injury: is psychostimulant medication beneficial?", J Head Trauma Rehabil, 13, pp.73~81 (1998)
- Mahalick DM, "Psychopharmacologic treatment of acquired attention disorders in children with brain injury", Pediatr Neurosurg, 29, pp.121~126 (1998)
- Hornyak JE, "The use of methylphenidate in paediatric traumatic brain injury", Pediatr Rehabil, 1, pp.15~17 (1997)
- Hellander M, "Medication-induced mania: ethical issues and the need for more research", J Child Adolesc Psychopharmacol, 13, pp.199~ (2003)
- Shibib S, "Stimulant induced psychosis", Child Adolesc Ment Health, 14, pp.20~23 (2009)
- Mosholder AD, "Hallucinations and other psychotic symptoms associated with the use of attention-deficit", hyperactivity disorder drugs in children, 2009, pp.123, 611~616
- American Psychiatric Association, "Diagnostic and statistical manual of mental disorders", American Psychiatric Association, ~ (2013)
- Czerniak SM, "Areas of the brain modulated by single-dose methylphenidate treatment in youth with ADHD during task-based fMRI: a systematic review", Harv Rev Psychiatry, 21, pp.151~162 (2013)
- Chakraborty K, "Methylphenidate-induced manialike symptoms", Indian J Pharmacol, 43, pp.80~81 (2011)
- Demeter CA, "Current research in child and adolescent bipolar disorder", Dialogues Clin Neurosci, 10, pp.215~228 (2008)
- Barnea-Goraly N, "Limbic and corpus callosum aberrations in adolescents with bipolar disorder: a tract-based spatial statistics analysis", Biol Psychiatry, 66, pp.238~244 (2009)
- Treble A, "Working memory and corpus callosum microstructural integrity after pediatric traumatic brain injury: a diffusion tensor tractography study", J Neurotrauma, 30, pp.1609~1619 (2013)
- Schwarzbold M, "Psychiatric disorders and traumatic brain injury", Neuropsychiatr Dis Treat, 4, pp.797~816 (2008)
- Murai T, "Rapid cycling bipolar disorder after left temporal polar damage", Brain Inj, 17, pp.355~358 (2003)
- Robinson RG, "Comparison of mania and depression after brain injury: causal factors", Am J Psychiatry, 145, pp.172~178 (1988)
- Jorge RE, "Secondary mania following traumatic brain injury", Am J Psychiatry, 150, pp.916~921 (1993)
- Shukla S, "Mania following head trauma", Am J Psychiatry, 144, pp.93~96 (1987)
- van Reekum R, "Psychiatric disorders after traumatic brain injury", Brain Inj, 10, pp.319~327 (1996)
- Deb S, "Rate of psychiatric illness 1 year after traumatic brain injury", Am J Psychiatry, 15, pp.374~378 (1999)
- Schachar RJ, "Mental health implications of traumatic brain injury (TBI) in children and youth", J Can Acad Child Adolesc Psychiatry, 24, pp.100~108 (2015)
