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고등각막표면굴절교정레이저절제술에서 근시교정량이 고위수차의 장기간 변화에 미치는 효과

Effects of Amount of Myopic Correction on Long-term Changes in Higher-order Wavefront Aberrations in ASA-PRK

이상범|김진선
대한안과학회 (The Korean Ophthalmological Society)|2010.09|대한안과학회지 (Journal of The Korean Ophthalmological Society)|제51권 제9호|pp. 1184-1195

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키워드

Long-term changePRKASA-PRKHigher-order wavefront aberrationMyopic correction
주제분류안과학

초록

목적: 고등각막표면굴절교정레이저절제술(ASA-PRK)에서 근시교정량에 따른 술 후 고위수차의 장기간 변화를 알아보고자 하였다. 대상과 방법: ASA-PRK를 시행한 101명 193안을 근시교정량의 중앙값에 따라 두 군으로 나누었다(1군 ≤ -4.37D, 97안, 평균 -3.26± 0.77D; 2군 ＞-4.37D, 96안, 평균 -5.77 ± 1.00D). 술 전과 술 후 1, 3, 6, 12, 24개월에 수차계로 총파면고위수차, 코마, 세조각및 구면수차를 측정하였고, 그 변화를 통계적으로 분석하였다. 결과: 세조각수차를 제외한 총파면고위수차, 코마 및 구면수차는 각 군별로 술 후 1, 3, 6, 12, 24개월에 술 전에 비해 증가하였고(p＜0.05),그 증가는 1군보다 2군이 더 심하였다(p＜0.05). 그 수차의 변화량은 단기간(1개월까지)에만 1군보다 2군이 높았고(p＜0.05), 중기간(1~6개월)과 장기간(6~24개월)에서는 두 군 간 차이가 없었다. 결론: 술 후 총파면고위수차, 코마 및 구면수차는 근시교정량이 많은 2군에서 더 높은 증가를 보였다. 그 증가는 술 후 1개월까지의단기간 변화에 기인하였으며 2년 동안 술 전 값으로 회귀 없이 유지되었다.

Abstract

Purpose: To evaluate the effects of the amount of myopic correction on long-term changes in higher-order wavefront aberrations (HOAs) in advanced surface ablation-photorefractive keratectomy (ASA-PRK). Methods: The 193 eyes of 101 patients who underwent ASA-PRK were divided into two groups according to the amount of myopic correction by the median value (Group 1 ≤ -4.37D, 97 eyes, mean -3.26 ± 0.77D; Group 2 > -4.37D, 96 eyes, mean -5.77 ± 1.00D). Wavefront aberrometry was performed to measure total HOA, coma, trefoil, and spherical aberration preoperatively and at 1, 3, 6, 12, and 24 months after ASA-PRK. Statistical analysis was performed to compare changes in all HOAs between the two groups. Results: Each magnitude of total HOA, coma, and spherical aberration except trefoil significantly increased at 1, 3, 6, 12,and 24 months postoperatively in each group (p<0.05), and the increases were statistically significantly higher in group 2compared to those of group 1 (p<0.05). The amount of changes in all HOAs except trefoil revealed that statistically significantly higher increases in group 2 compared to those of group 1 were determined only in the short-term period (up to 1month, p<0.05), but not in the medium-term (1 to 6 months) or long-term periods (6 to 24 months). Conclusions: Postoperative total HOA, coma, and spherical aberration significantly increased in both groups, and these increases in surgery-induced HOAs were significantly higher in group 2 (> -4.37D). Increases in ASA-PRK-induced HOAs primarily originated from short-term changes in the postoperative one-month period and did not return to the preoperative level during the postoperative two-year period.

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