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라식 혹은 라섹 후 근시퇴행 시 안압하강제와 0.1% 플루오로메토론의 병합치료 효과

The Effect of Anti-glaucoma Eyedrops and 0.1% Fluorometholone on Myopic Regression after LASIK or LASEK

김희선|이희경|김정섭|김진국|김욱겸|류익희
대한안과학회 (The Korean Ophthalmological Society)|2017.01|대한안과학회지 (Journal of The Korean Ophthalmological Society)|제58권 제1호|pp. 13-20

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참고문헌

키워드

Anti-glaucoma eyedropsMyopic regressionLaser-assisted in-situ keratomileusis (LASIK)Laser-assisted sub-epithelial keratectomy (LASEK)Fluorometholone
주제분류안과학

초록

목적: 라식 라섹 후 근시퇴행으로 인해 시력저하를 호소하는 환자에서 안압하강제와 0.1% 플루오로메토론을 함께 사용하여 약물치료를 시행하였을 때 시력과 굴절값에 미치는 효과를 알아보고자 하였다. 대상과 방법: 본원에서 라식 혹은 라섹 수술을 받은 환자 중 2015년 1월부터 2016년 1월까지 시력저하로 내원하여 근시퇴행으로 진단받고 약물치료를 받은 환자 155명(155안)을 대상으로 약물치료 전후의 시력 및 굴절이상을 비교하고, 라식 라섹에서 그 결과가 차이 있는지 알아보았다. 결과: 약물치료 시작 시기는 수술 후 평균 64.1 ± 36.8개월 후였다. 약물치료 후 시력이 호전되고 근시량이 감소한 약물치료 반응군은 63명(41%)이었으며, 이들에서 시력 호전은 -0.21 ± 0.11 logMAR, 근시량의 감소는 0.56 ± 0.32디옵터였다. 약물치료 반응군 중 완전히 회복되는 경우는 24명(15%), 부분적으로 회복된 경우는 39명(26%)이었다. 약물치료에 시력이 호전되는 빈도는 라섹 후보다 라식 후에 더 높았으나 통계적으로 유의하지는 않았다. 결론: 라식 라섹 후 근시퇴행으로 인한 시력저하 시 안압 하강제와 0.1% 플루오로메토론을 함께 사용한 약물치료는 약 41% 환자에서 시력을 호전시킬 수 있는 방법이며, 라식, 라섹 후 모두에서 효과적인 방법이다.

Abstract

Purpose: To evaluate the effect of combined medical treatment with anti-glaucoma eyedrops and 0.1% fluorometholone on visual acuity and refractive errors in patients complaining of blurred vision due to myopic regression after laser-assisted in-situ keratomileusis (LASIK) or laser-assisted sub-epithelial keratectomy (LASEK). Methods: This study comprised 155 patients (155 eyes) who were diagnosed with myopic regression after LASIK or LASEK and received medical treatment from January 2015 to January 2016. The visual acuity and refractive errors were compared before and after medical treatment and evaluated to determine whether the results differ between LASIK and LASEK. Results: The mean time of medical treatment was 64.1 ± 36.8 months after surgery. The responder group whose vision was improved and whose myopic error was decreased after medical treatment was comprised of 63 patients (41%). Their visual acuity in this group improved -0.21 ± 0.11 logMAR, and the amount of myopic error decreased 0.56 ± 0.32 diopters. The full responder group was 24 patients (15%), and the partial responder group was 39 patients (26%). The frequency of response to medical treatment was higher after LASIK than after LASEK, but the difference was not statistically significant. Conclusions: The combined medical treatment with anti-glaucoma eyedrops and 0.1% fluorometholone was effective in 41% of patients with regard to visual acuity improvement when used for post-LASIK or post-LASEK myopic regression. The medical treatment was effective after both LASIK and LASEK.

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