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거짓비늘증후군과 급성폐쇄각발작의 생체계측 특성 비교

Biometric Characteristics in Eyes with Pseudoexfoliation Syndrome and Eyes with Acute Angle Closure

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목적: 거짓비늘증후군 환자군에서 전방깊이에 따른 생체계측치를 급성폐쇄각발작 환자군 및 대조군과 비교하여 생체계측 특성을 알아보고자 한다. 대상과 방법: 총 121명 130안(거짓비늘증후군 49안, 급성폐쇄각발작 28안, 대조군 53안)을 대상으로 IOL Master® 700으로 생체계측을하였다. 거짓비늘증후군 환자군(PXall군)을 전방깊이 2.70 mm를 기준으로 전방깊이가 깊은 군(PXd군)과 전방깊이가 얕은 군(PXs군) 으로 나눈 후 급성폐쇄각발작 환자군 및 대조군과 안축장, 전방깊이, 수정체두께를 비교하였다. 결과: PXall군과 대조군의 비교에서는 안축장은 유의한 차이를 보이지 않았지만, PXall군에서 대조군에 비해서 전방은 얕고 수정체두께는 두꺼웠다. 그러나 전방깊이에 따라 PXall군을 두 군으로 나누어서 대조군과 비교해보면, PXd군은 수정체두께에서 대조군과 차이를 보이지 않았지만(p=0.113) PXs군은 PXd군과 대조군에 비해 수정체가 두꺼웠다(p<0.001, p<0.001). PXs군은 급성폐쇄각발작 환자군에 비해서 안축장은 상대적으로 길었지만(p=0.025), 수정체두께 및 안축장에 대한 수정체두께의 비에서는 유의한 차이가 없었다(p=0.222, p=0.076). 결론: 거짓비늘증후군 환자군에서 전방깊이에 따라 생체계측의 특성에 차이가 있었다. 전방깊이가 깊은 거짓비늘증후군 환자군은 대조군과 생체계측의 특성에 유의한 차이가 없었지만, 전방깊이가 얕은 거짓비늘증후군 환자군은 급성폐쇄각발작 환자군과 유사하게수정체가 두꺼웠으며, 안축장에 대한 수정체두께의 비도 유의한 차이가 없었다.

Abstract

Purpose: To investigate the biometric characteristics of eyes with pseudoexfoliation syndrome (PEX) according to the anterior chamber depth (ACD) by comparing them to patients with acute angle closure (AAC) and a control group. Methods: A total of 130 eyes of 121 subjects (PEX, 49 eyes; AAC, 28 eyes; and control, 53 eyes) were included in the study. Axial length (AL), ACD, and lens thickness (LT) were measured with an IOL Master® 700 (Carl Zeiss Meditec, Jena, Germany). The total PEX (PXall) group was divided into a PEX with deep ACD group (PXd) and a shallow ACD group (PXs) based on an ACD of 2.70 mm. We compared the biometric results among the PXall, PXd, PXs, AAC, and control groups. Results: There was no significant difference in AL between the PXall and control groups; however, the PXall group had a shallower ACD and thicker lenses. After dividing the PXall group into two groups based on ACD, the PXd group showed no difference in LT compared to the control group (p = 0.113). The LT of the PXs group was thicker than those of the PXd and control groups (p < 0.001 and p < 0.001, respectively). The PXs group had longer ALs than the AAC group (p = 0.025); however, there was no difference in LT or in the ratio of LT to AL (p = 0.222 and p = 0.076, respectively). Conclusions: The biometric characteristics were different in eyes with PEX based on ACD. PEX patients with deep ACDs showed no difference in biometry compared to the control group; however, PEX patients with shallow ACDs showed characteristics of a thick LT, similar to AAC patients. There was no difference in the ratio of LT to AL among groups.

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