일측 이명 환자에서의 청성뇌간반응 결과의 양이비교 분석
Interaural Comparison of Audiotory Brainstem Response in Unilateral Tinnitus Patients
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Background and Objectives Tinnitus is a common symptom in otolaryngology. Whilethere have been some animal studies of unique findings in auditory brainstem response (ABR),there have not been much reports related to ABR waves and tinnitus. Recently, some humanstudies have been reported on the specific characteristics of ABR wave in tinnitus patients. Inthis study, we compared waveform characteristics of the tinnitus ear with those of non-tinnitusear in unilateral tinnitus patients. Subjects and Method A retrospective review was carried out for 101 patients, who had beenenrolled from January 2011 to April 2016 for the treatment of unilateral tinnitus. ABR parametersbetween the tinnitus ear and the normal ear were compared. The entire population was dividedinto two groups, a right tinnitus group and a left tinnitus group, and each group was comparedinteraurally. Results Latency delay and amplitude differences were observed in the ipsilesional wave III,but the ratio differences were not significant. The right tinnitus patient group showed an increasedamplitude but no latency delay in the wave III and V. The left tinnitus patient group showed alatency delay in the wave I, III, and V and a decreased amplitude difference in the wave III. Conclusion When the ABR waveform of unilateral tinnitus patients were compared interaurally,different ABR characteristics were observed between the right and left tinnitus. This mayraise the possibility of a different pathophysiologic mechanism between the right and left ear.
Abstract
Background and Objectives Tinnitus is a common symptom in otolaryngology. Whilethere have been some animal studies of unique findings in auditory brainstem response (ABR),there have not been much reports related to ABR waves and tinnitus. Recently, some humanstudies have been reported on the specific characteristics of ABR wave in tinnitus patients. Inthis study, we compared waveform characteristics of the tinnitus ear with those of non-tinnitusear in unilateral tinnitus patients. Subjects and Method A retrospective review was carried out for 101 patients, who had beenenrolled from January 2011 to April 2016 for the treatment of unilateral tinnitus. ABR parametersbetween the tinnitus ear and the normal ear were compared. The entire population was dividedinto two groups, a right tinnitus group and a left tinnitus group, and each group was comparedinteraurally. Results Latency delay and amplitude differences were observed in the ipsilesional wave III,but the ratio differences were not significant. The right tinnitus patient group showed an increasedamplitude but no latency delay in the wave III and V. The left tinnitus patient group showed alatency delay in the wave I, III, and V and a decreased amplitude difference in the wave III. Conclusion When the ABR waveform of unilateral tinnitus patients were compared interaurally,different ABR characteristics were observed between the right and left tinnitus. This mayraise the possibility of a different pathophysiologic mechanism between the right and left ear.
참고문헌 (21)
- Park GY, "Traumatic ossicular disruption with isolated fracture of the stapes suprastructure: comparison with incudostapedial joint dislocation", Acta Otolaryngol, 134(12), pp.1225~1230 (2014)[DOI]
- Gu JW, "Brainstem auditory evoked potentials suggest a role for the ventral cochlear nucleus in tinnitus", J Assoc Res Otolaryngol, 13(6), pp.819~833 (2012)[DOI]
- Davis AC, "The prevalence of hearing impairment and reported hearing disability among adults in Great Britain", Int J Epidemiol, 18(4), pp.911~917 (1989)[DOI]
- Joo YH, "Association of hearing loss and tinnitus with health-related quality of life: the Korea National Health and Nutrition Examination Survey", PLoS One, 10(6), pp.e0131247~ (2015)[DOI]
- Kral A, "On lateral inhibition in the auditory system", Gen Physiol Biophys, 15(2), pp.109~127 (1996)
- Brozoski TJ, "Vigabatrin, a GABA transaminase inhibitor, reversibly eliminates tinnitus in an animal model", J Assoc Res Otolaryngol, 8(1), pp.105~118 (2007)[DOI]
- 유신영, "우리나라(한국) 대학병원의 주관적 이명 치료 현황", 대한이비인후-두경부외과학회지, 56(5), pp.266~277 (2013), 대한이비인후과학회[DOI]
- 장지원, "우리나라(한국)의 이명검사 현황 및 이명검사 방법제안", 대한이비인후-두경부외과학회지, 57(10), pp.671~686 (2014), 대한이비인후과학회[DOI]
- Dehmel S, "Gap prepulse inhibition and auditory brainstem-evoked potentials as objective measures for tinnitus in guinea pigs", Front Syst Neurosci, 6, pp.42~ (2012)
- Godey B, "Sensitivity of auditory brainstem response in acoustic neuroma screening", Acta Otolaryngol, 118(4), pp.501~504 (1998)[DOI]
- Kim CS, "Clinical study on auditory brainstem response", Korean J Otorhinolaryngol-Head Neck Surg, 28(3), pp.279~283 (1985)
- Moon IH, "Tinnitus masking effects using various kinds of sound and music", Korean J Otolaryngol-Head Neck Surg, 42(2), pp.173~183 (1999)
- Barnea G, "Tinnitus with normal hearing sensitivity: extended high-frequency audiometry and auditorynerve brain-stem-evoked responses", Audiology, 29(1), pp.36~45 (1990)[DOI]
- Ikner CL, "The effect of tinnitus on ABR latencies", Ear Hear, 11(1), pp.16~20 (1990)
- Kehrle HM, "Comparison of auditory brainstem response results in normal-hearing patients with and without tinnitus", Arch Otolaryngol Head Neck Surg, 134(6), pp.647~651 (2008)[DOI]
- Schaette R, "Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model", J Neurosci, 31(38), pp.13452~13457 (2011)[DOI]
- Brackmann DE, "Assessing recovery of facial function following acoustic neuroma surgery", Otolaryngol Head Neck Surg, 92(1), pp.88~93 (1984)[DOI]
- Lanting CP1, "Functional imaging of unilateral tinnitus using fMRI", Acta Otolaryngol, 128(4), pp.415~421 (2008)[DOI]
- 정다정, "이명의 발생기전", 대한이비인후-두경부외과학회지, 57(6), pp.357~363 (2014), 대한이비인후과학회[DOI]
- Norena AJ, "An integrative model of tinnitus based on a central gain controlling neural sensitivity", Neurosci Biobehav Rev, 35(5), pp.1089~1109 (2011)[DOI]
- Lenarz T, "Neural mechanisms of tinnitus", Eur Arch Otorhinolaryngol, 249(8), pp.441~446 (1993)