대구지역의 COVID-19 감염으로 인한 후각 및 미각장애의 특징과 예
Characteristics and Prognosis of COVID-19 Induced Olfactory and Gustatory Dysfunction in Daegu
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Background and Objectives Olfactory and gustatory dysfunctions have been known ascharacteristic symptoms of coronavirus disease 2019 (COVID-19). However, the study of theclinical features of olfactory and gustatory dysfunctions in COVID-19 is still insufficient. Subjects and Method Mild COVID-19 patients who complained of olfactory or gustatorydysfunctions in the telephone monitoring from March 8 to April 8, 2020 were included in thisstudy. Patient information was collected using a Google questionnaire. COVID-19 symptoms,severity and improvement of olfactory and gustatory dysfunctions of patients were investigated. Results A total of 228 patients participated in this study. The number of male and femalewere 76 and 152, and the average age was 32.1±11.5 years. There were 210 patients (92.1%) ofolfactory dysfunction, 179 patients (78.5%) of gustatory dysfunction, and 165 patients (71.4%)who complained of both symptoms. The 18.4% of patients complained only olfactory or gustatorydysfunction without other symptoms of COVID-19, and 51.1% of patients presented olfactoryand gustatory dysfunctions as the first symptoms. Most of the patients (95.6%) improvedolfactory and gustatory dysfunctions within several months, but only 79.8% of patientswere normalized. Conclusion Since olfactory and gustatory dysfunctions are the first symptoms in the numerousCOVID-19 patients, and continued research on these patients play an important role inthe screening and prevention of COVID-19. Long-term observation and further studies oftreatment are needed for 20.2% of patients who have not fully recovered.
Abstract
Background and Objectives Olfactory and gustatory dysfunctions have been known ascharacteristic symptoms of coronavirus disease 2019 (COVID-19). However, the study of theclinical features of olfactory and gustatory dysfunctions in COVID-19 is still insufficient. Subjects and Method Mild COVID-19 patients who complained of olfactory or gustatorydysfunctions in the telephone monitoring from March 8 to April 8, 2020 were included in thisstudy. Patient information was collected using a Google questionnaire. COVID-19 symptoms,severity and improvement of olfactory and gustatory dysfunctions of patients were investigated. Results A total of 228 patients participated in this study. The number of male and femalewere 76 and 152, and the average age was 32.1±11.5 years. There were 210 patients (92.1%) ofolfactory dysfunction, 179 patients (78.5%) of gustatory dysfunction, and 165 patients (71.4%)who complained of both symptoms. The 18.4% of patients complained only olfactory or gustatorydysfunction without other symptoms of COVID-19, and 51.1% of patients presented olfactoryand gustatory dysfunctions as the first symptoms. Most of the patients (95.6%) improvedolfactory and gustatory dysfunctions within several months, but only 79.8% of patientswere normalized. Conclusion Since olfactory and gustatory dysfunctions are the first symptoms in the numerousCOVID-19 patients, and continued research on these patients play an important role inthe screening and prevention of COVID-19. Long-term observation and further studies oftreatment are needed for 20.2% of patients who have not fully recovered.
참고문헌 (18)
- Lechien JR, "Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease(COVID-19) : A multicenter European study", Eur Arch Otorhinolaryngol, 277(8), pp.2251~2261 (2020)
- Cucinotta D, "WHO declares COVID-19 a pandemic", Acta Biomed, 91(1), pp.157~160 (2020)
- Lovato A, "Upper airway symptoms in coronavirus disease 2019(COVID-19)", Am J Otolaryngol, 41(3), pp.102474~ (2020)
- Mao L, "Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China", JAMA Neurol, 77(6), pp.683~690 (2020)
- Moein ST, "Smell dysfunction : A biomarker for COVID-19", Int Forum Allergy Rhinol, 10(8), pp.944~950 (2020)
- Huart C, "Comparison of COVID-19 and common cold chemosensory dysfunction", Rhinology, 58(6), pp.623~625 (2020)
- Seiden AM, "Postviral olfactory loss", Otolaryngol Clin North Am, 37(6), pp.1159~1166 (2004)
- Beltrán-Corbellini Á, "Acute-onset smell and taste disorders in the context of COVID-19 : A pilot multicentre polymerase chain reaction based case-control study", Eur J Neurol, 27(9), pp.1738~1741 (2020)
- Gane SB, "Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome?", Rhinology, 58(3), pp.299~301 (2020)
- Costa KVTD, "Olfactory and taste disorders in COVID-19 : A systematic review", Braz J Otorhinolaryngol, 86(6), pp.781~792 (2020)
- Meng X, "COVID-19 and anosmia : A review based on up-to-date knowledge", Am J Otolaryngol, 41(5), pp.102581~ (2020)
- Yonghyun Lee, "Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients", Journal of Korean Medical Science, 35(18), pp.1~6 (2020), 대한의학회[DOI]
- Vaira LA, "Anosmia and ageusia : Common findings in COVID-19 patients", Laryngoscope, 130(7), pp.1787~ (2020)
- Vaira LA, "Validation of a self-administered olfactory and gustatory test for the remotely evaluation of COVID-19 patients in home quarantine", Head Neck, 42(7), pp.1570~1576 (2020)
- Bagheri SH, "Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran", Med J Islam Repub Iran, 34(6), pp.62~ (2020)
- Dell’Era V, "Smell and taste disorders during COVID-19 outbreak : Crosssectional study on 355 patients", Head Neck, 42(7), pp.1591~1596 (2020)
- Hopkins C, "Early recovery following new onset anosmia during the COVID-19 pandemic-an observational cohort study", J Otolaryngol Head Neck Surg, 49(1), pp.26~ (2020)
- Kaye R, "COVID-19 anosmia reporting tool : Initial findings", Otolaryngol Head Neck Surg, 163(1), pp.132~134 (2020)