Clinical Characteristics of Colonic Diverticulosis in Korea: A Prospective Study
2
조회
0
다운로드
11
인용
0
참고문헌
키워드
초록
Background/Aims: The prevalence of colonic diverticulosis has been reported to be lower in Korea than in Western countries. This disease also shows markedly different characteristics in the Korean population. We describe herein a prospective investigation, based on colonoscopic examination, of the prevalence, clinical characteristics, and factors associated with colonic diverticulosis in Korea. Methods: We prospectively analyzed data from 848 patients who underwent colonoscopy between July and October 2008 in Seoul Paik hospital. Clinical features such as the presence of diverticula and their location and number were assessed. Information on the subjects’ symptoms, body mass index, diet, underlying disease, and alcohol and smoking habits was obtained through completion of a questionnaire. Results: The overall prevalence of colonic diverticulosis was 12.1% (103 / 848). The right side of the colon was involved in 84.5% of patients (87 / 103); patients with right side diverticula were, on average, younger than those with left side diverticulosis (p = 0.014). Multiple diverticula were observed in 60.2% (62 / 103) of patients. Age greater than 60 years, a high-fat diet, and alcohol consumption were significantly associated with the presence of colonic diverticulosis (p < 0.05). Conclusions: The prevalence of colonic diverticulosis in Korea is increasing and is most commonly located in the right side of the colon. Further, old age and diet may affect the risk of development of this disease. (Korean J Intern Med 2010;25:140-146)
Abstract
Background/Aims: The prevalence of colonic diverticulosis has been reported to be lower in Korea than in Western countries. This disease also shows markedly different characteristics in the Korean population. We describe herein a prospective investigation, based on colonoscopic examination, of the prevalence, clinical characteristics, and factors associated with colonic diverticulosis in Korea. Methods: We prospectively analyzed data from 848 patients who underwent colonoscopy between July and October 2008 in Seoul Paik hospital. Clinical features such as the presence of diverticula and their location and number were assessed. Information on the subjects’ symptoms, body mass index, diet, underlying disease, and alcohol and smoking habits was obtained through completion of a questionnaire. Results: The overall prevalence of colonic diverticulosis was 12.1% (103 / 848). The right side of the colon was involved in 84.5% of patients (87 / 103); patients with right side diverticula were, on average, younger than those with left side diverticulosis (p = 0.014). Multiple diverticula were observed in 60.2% (62 / 103) of patients. Age greater than 60 years, a high-fat diet, and alcohol consumption were significantly associated with the presence of colonic diverticulosis (p < 0.05). Conclusions: The prevalence of colonic diverticulosis in Korea is increasing and is most commonly located in the right side of the colon. Further, old age and diet may affect the risk of development of this disease. (Korean J Intern Med 2010;25:140-146)
참고문헌 (30)
- Simpson J, "Pathogenesis of colnoic diverticula", Br J Surg, 89, pp.546~554 (2002)
- Stollman NH, "Diverticular disease of the colon", J Clin Gastroenterol, 29, pp.241~252 (1999)
- Bogardus ST Jr, "What do we know about diverticular disease? A brief overview", J Clin Gastroenterol, 40, pp.S108~S111 (2006)
- Parra-Blanco A, "Colonic diverticular disease: pathophysiology and clinical picture", Digestion, 73, pp.47~57 (2006)
- Heise CP, "Epidemiology and pathogenesis of diverticular disease", J Gastrointest Surg, 12, pp.1309~1311 (2008)
- Sheth AA, "Diverticular disease and diverticulitis", Am J Gastroenterol, 103, pp.1~7 (2008)
- Painter NS, "Diverticular disease of the colon: a deficiency disease of Western civilization", Br Med J, 2, pp.450~454 (1971)
- Martel J, "History, incidence, and epidemiology of diverticulosis", J Clin Gastroenterol, 42, pp.1125~1127 (2008)
- Kim KS, "Recent changes of colonic diverticulosis in Korea", J Korea Radiol Soc, 20, pp.632~638 (1984)
- Kim KH, "A clinical study of diverticulosis of the colon", J Korea Med Ass, 29, pp.63~68 (1986)
- Kim BH, "Diverticular disease of the colon in Korea", Korean J Intern Med, 2, pp.79~83 (1987)
- Kwoen YT, "Changing incidence of diverticular disease of the colon in Korea: a serial radiologic study (report iii)", J Korea Radiol Soc, 24, pp.840~843 (1988)
- Lee YJ, "The incidence and characteristics of colonic diverticulosis in the west Kangwondo", J Korean Surg Soc, 39, pp.121~132 (1990)
- Son MY, "Radiologic analysis of developmental pattern in colonic diverticulosis", Korean J Gastroenterol, 22, pp.94~99 (1990)
- Ko JK, "Colonic diverticulosis: evaluation with double contrast barium enema", J Korean Radiol Soc, 36, pp.285~289 (1997)
- 최창수, "대장내시경검사로 진단된 대장게실증의 발생 빈도 및 임상양상", Clinical Endoscopy, 35(3), pp.146~151 (2007), 대한소화기내시경학회
- 김화영, "한국 성인의 영양 위험군 진단을 위한 식생활진단표의 개발과 타당성 검증에 관한 연구", 한국영양학회지, 36(1), pp.83~92 (2003), 한국영양학회
- 한동수, "다량의 복수가 주 증상으로 나타난 POEMS 증후군 1예", 대한소화기학회지, 40(3), pp.1~1 (2002), 대한소화기학회
- 송정훈, "대장내시경검사로 진단된 대장 게실 질환의 임상적 고찰", Intestinal research, 6(2), pp.110~115 (2008), 대한장연구학회
- Sugihara K, "Diverticular disease of the colon in Japan: a review of 615 cases", Dis Colon Rectum, 27, pp.531~537 (1984)
- Sugihara K, "Diverticular disease of the colon in Japan", Ann Acad Med Singapore, 16, pp.504~508 (1987)
- Munakata A, "Epidemiological evaluation of colonic diverticulosis and dietary fiber in Japan", Tohoku J Exp Med, 171, pp.145~151 (1993)
- Nakada I, "Diverticular disease of the colon at a regional general hospital in Japan", Dis Colon Rectum, 38, pp.755~759 (1995)
- Chia JG, "Trends of diverticular disease of the large bowel in a newly developed country", Dis Colon Rectum, 34, pp.498~501 (1991)
- Nakaji S, "Comparison of etiology of right-sided diverticula in Japan with that of left-sided diverticula in the West", Int J Colorectal Dis, 17, pp.365~373 (2002)
- Aldoori WH, "A prospective study of diet and the risk of symptomatic diverticular disease in men", Am J Clin Nutr, 60, pp.757~764 (1994)
- Aldoori WH, "A prospective study of dietary fiber types and symptomatic diverticular disease in men", J Nutr, 128, pp.714~719 (1998)
- Aldoori W, "Preventing diverticular disease: review of recent evidence on high-fibre diets", Can Fam Physician, 48, pp.1632~1637 (2002)