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Topical Steroids to Treat Granulomatous Mastitis: A Case Report

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초록

Idiopathic granulomatous mastitis (IGM) is a rare and chronic benign disease of the breast. Histologically, the disease presents as an intense inflammatory reaction with non-caseated granulomas that are the characteristic symptom of the disease. No consensus exists on the best treatment modality for this disease. In this report, we present a patient with granulomatous mastitis who was treated successfully with low-dose oral and topical steroids. Our aim here is to discuss various approaches for IGM in view of the literature and present treatment with topical steroids, which has not been reported.

Abstract

Idiopathic granulomatous mastitis (IGM) is a rare and chronic benign disease of the breast. Histologically, the disease presents as an intense inflammatory reaction with non-caseated granulomas that are the characteristic symptom of the disease. No consensus exists on the best treatment modality for this disease. In this report, we present a patient with granulomatous mastitis who was treated successfully with low-dose oral and topical steroids. Our aim here is to discuss various approaches for IGM in view of the literature and present treatment with topical steroids, which has not been reported.

참고문헌 (10)

  1. Kessler E, "Granulomatous mastitis: a lesion clinically simulating carcinoma", Am J Clin Pathol, 58, pp.642~646 (1972)
  2. Lai EC, "The role of conservative treatment in idiopathic granulomatous mastitis", Breast J, 11, pp.454~456 (2005)
  3. Su FH, "Sister Mary Ann Lou. Idiopathic granulomatous mastitis: a case successfully treated with a minimum dose of a steroid", Chang Gung Med J, 28, pp.431~435 (2005)
  4. Asoglu O, "Feasibility of surgical management in patients with granulomatous mastitis", Breast J, 11, pp.108~114 (2005)
  5. Kim J, "Methotrexate in the management of granulomatous mastitis", ANZ J Surg, 73, pp.247~249 (2003)
  6. 이제희, "Radiologic and Clinical Features of Idiopathic Granulomatous Lobular Mastitis Mimicking Advanced Breast Cancer", Yonsei Medical Journal, 47(1), pp.78~84 (2006), 연세대학교의과대학
  7. DeHertogh DA, "Prednisone management of granulomatous mastitis", N Engl J Med, 303, pp.799~800 (1980)
  8. Maffini F, "Systemic therapy as a first choice treatment for idiopathic granulomatous mastitis", J Cutan Pathol, 36, pp.689~691 (2009)
  9. Buys LM, "Treatment options for atopic dermatitis", Am Fam Physician, 75, pp.523~528 (2007)
  10. Hanifin J, "Intermittent dosing of fluticasone propionate cream for reducing the risk of relapse in atopic dermatitis patients", Br J Dermatol, 147, pp.528~537 (2002)

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