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Eosinophilic Mastitis: A Case Report

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Eosinophilic mastitis is a rare disease in which eosinophils infiltrate the ducts and lobules of the breast, causing mammary inflammation. Although eosinophilic mastitis is a benign condition, it presents similarly to and is often mistaken for breast cancer. Here we report the first case of eosinophilic mastitis in Korea. A 43-year-old woman presented with redness and swelling in her right breast. A breast ultrasound revealed ill-defined isoechoic and hyperechoic areas in the upper half and lower inner quadrant of the right breast combined with axillary level I lymphadenopathy. A histopathological examination by core needle biopsy demonstrated lymphoplasma cell infiltration with eosinophils. A peripheral blood examination revealed an eosinophil count of 5,000/mm³. The patient was treated with oral steroids, antibiotics, and leukotriene receptor antagonists. Four months later, the eosinophil count had returned to normal, and breast ultrasound exhibited marked improvement.

Abstract

Eosinophilic mastitis is a rare disease in which eosinophils infiltrate the ducts and lobules of the breast, causing mammary inflammation. Although eosinophilic mastitis is a benign condition, it presents similarly to and is often mistaken for breast cancer. Here we report the first case of eosinophilic mastitis in Korea. A 43-year-old woman presented with redness and swelling in her right breast. A breast ultrasound revealed ill-defined isoechoic and hyperechoic areas in the upper half and lower inner quadrant of the right breast combined with axillary level I lymphadenopathy. A histopathological examination by core needle biopsy demonstrated lymphoplasma cell infiltration with eosinophils. A peripheral blood examination revealed an eosinophil count of 5,000/mm³. The patient was treated with oral steroids, antibiotics, and leukotriene receptor antagonists. Four months later, the eosinophil count had returned to normal, and breast ultrasound exhibited marked improvement.

참고문헌 (8)

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  4. Takahashi K, "A very rare case of eosinophilic mastitis", Int J Surg Case Rep, 49, pp.251~254 (2018)
  5. Garg M, "Eosinophilic mastitis masquerading as breast carcinoma", J Surg Case Rep, 2012, pp.1~ (2012)
  6. Komenaka IK, "Recurrent eosinophilic mastitis", Am Surg, 69, pp.620~623 (2003)
  7. Villalba-Nuno V, "Churg-Strauss syndrome involving the breast : a rare cause of eosinophilic mastitis", Eur Radiol, 12, pp.646~649 (2002)
  8. Thompson AB, "The hypereosinophilic syndrome presenting with eosinophilic mastitis", Arch Intern Med, 145, pp.564~565 (1985)

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