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Is tenofovir disoproxil fumarate an all-powerful weapon in the treatment of chronic hepatitis B?

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In conclusion, while TDF-based therapy is a promisingapproach and is currently the best option in themanagement of CHB patients with antiviral resistance,we do not have sufficient data to conclude that TDF isthe all-powerful drug suggested by some studies. Longtermfollow-up data from well-designed trials will allowphysicians to select the best therapeutic options fortheir patients with antiviral-resistant CHB.

Abstract

In conclusion, while TDF-based therapy is a promisingapproach and is currently the best option in themanagement of CHB patients with antiviral resistance,we do not have sufficient data to conclude that TDF isthe all-powerful drug suggested by some studies. Longtermfollow-up data from well-designed trials will allowphysicians to select the best therapeutic options fortheir patients with antiviral-resistant CHB.

참고문헌 (13)

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  13. Kwon SY, "Tenofovir is effective alone or with entecavir in entecavir-resistant patients with chronic-hepatitis B virus infection: multicenter randomized trial", Clin Mol Hepatol, 20, pp.S5~ (2014)

관련 논문AI추천

Management of Antiviral Resistance in Chronic Hepatitis B임영석거트앤리버 소화기연관학회협의회 · Gut and Liver2017 · 제11권 제2호Efficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir김형래, 노진희, 박능화, 신정우, 안재성, 양유진, 이재호, 전희정, 정석원대한간학회 · Clinical and Molecular Hepatology2017 · 제23권 제3호Comparison of tenofovir plus lamivudine versus tenofovir monotherapy in patients with lamivudine-resistant chronic hepatitis B박능화, 박용태, 박찬호, 배미애, 신정우, 이윤임, 정석원, 정화식대한간학회 · Clinical and Molecular Hepatology2016 · 제22권 제1호Efficacy and Safety of Tenofovir-Based Rescue Therapy for Chronic Hepatitis B Patients with Previous Nucleo(s/t)ide Treatment Failure권소영, 김윤수, 김정한, 김주현, 변관수, 연종은, 이창홍, 이초이, 최원혁, Eileen L. Yoon거트앤리버 소화기연관학회협의회 · Gut and Liver2014 · 제8권 제1호Tenofovir disoproxil fumarate monotherapy for nucleos(t)ide analogue-naïve and nucleos(t)ide analogue-experienced chronic hepatitis B patients김경아, 백우현, 이준성, 정상경, Bu Hyun Lee, Hyun Kyo Lee, Jong Wook Kim, Nam-Hoon Kim, So Young Ha, Won Ki Bae, Yoon Jung Jwa, Young Doo Kim대한간학회 · Clinical and Molecular Hepatology2015 · 제21권 제1호Tenofovir has inferior efficacy in adefovir-experienced chronic hepatitis B patients compared to nucleos(t)idenaïve patients김윤준, 김휘영, 유수종, 유정주, 윤정환, 이동현, 이민종, 이정훈, 정고은, 조유리, 조은주, Fabien Zoulim대한간학회 · Clinical and Molecular Hepatology2017 · 제23권 제1호

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