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급성 뇌경색 치료를 위한 혈전 용해제 사용 후 발생한 척수 경막하 혈종-증례보고-

Spinal Subdural Hematoma Associated with Anticoagulant Treatment for Acute Cerebral Infarct-A case report-

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초록

Spinal subdural hematoma (SDH) is a rare cause of acute spinal cord compression. In most cases, these lesions are observed in association with lumbar puncture or spinal anesthesia, coagulation defect, or an underlying vascular malformation. The use of anticoagulant drug is recommended in managing deep vein thrombosis, acute myocardiac infarct, or acute cerebral infarct. But the risk of bleeding in major organs still exists and is increased by the use of multiple anticoagulants and the intensity of anticoagulation. The risk of spinal hematoma is increased in anticoagulated patients who undergo lumbar puncture or spinal anesthesia. But to dates, there are extremely rare cases of spontaneous spinal SDH occurring in patients with anticoagulant therapy when spinal instrumentation is not also being used. With reviewing some of literatures, we present a case of acute spontaneous spinal SDH developed whilereceiving anticoagulant therapy for treating acute cerebral infarct.

Abstract

Spinal subdural hematoma (SDH) is a rare cause of acute spinal cord compression. In most cases, these lesions are observed in association with lumbar puncture or spinal anesthesia, coagulation defect, or an underlying vascular malformation. The use of anticoagulant drug is recommended in managing deep vein thrombosis, acute myocardiac infarct, or acute cerebral infarct. But the risk of bleeding in major organs still exists and is increased by the use of multiple anticoagulants and the intensity of anticoagulation. The risk of spinal hematoma is increased in anticoagulated patients who undergo lumbar puncture or spinal anesthesia. But to dates, there are extremely rare cases of spontaneous spinal SDH occurring in patients with anticoagulant therapy when spinal instrumentation is not also being used. With reviewing some of literatures, we present a case of acute spontaneous spinal SDH developed whilereceiving anticoagulant therapy for treating acute cerebral infarct.

참고문헌 (10)

  1. Kuker W, "Spinal subdural and epidural haematoma: diagnostic and therapeutic aspects in acute and subacute cases", Acta Neurochir, 142, pp.777~785 (2000)
  2. Hausmann, Kirsch E, "Coagulopathy induced spinal intradural extramedullary haematoma: report of three cases and review of the literature", Acta Neurochir, 143, pp.135~140 (2001)
  3. Rayton KF, "Recommendations for anticoagulated patients undergoing image-guided spinal procedures", AJNR Am J Neuroradio, 27, pp.468~470 (2006)
  4. Russel NA, "Spinal subdural haematoma. A review", Surg Neurol, 20, pp.133~137 (1983)
  5. Jimbo H, "Spinal chronic subdural hematoma in association with anticoagulant therapy: a case report and literature review", Spine, 31, pp.E184~E187 (2006)
  6. Sari A, "Subacute spinal subdural hematoma associated with intracranial subdural hematoma", J Neuroradiol, 33, pp.67~69 (2006)
  7. Mashiko R, "Lumbosacral subdural hematoma. Case report", Neurol Med Chir (Tokyo), 46, pp.258~261 (2006)
  8. Kyriakides AE, "Acute spontaneous spinal subdural hematoma presenting as paraplegia", Spine, 32, pp.619~622 (2007)
  9. Miller DR, "Spinal subdural haematoma: how relevant is the INR?", Spinal Cord, 42, pp.477~480 (2004)
  10. Cha YH, "Spontaneous spinal subdural hematoma associated with low-molecular-weight heparin", J Neurosurg, 2, pp.612~613 (2005)

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