Novel Influenza A (H1N1)-Associated Acute Necrotizing Encephalopathy: A Case Report
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Several cases of acute necrotizing encephalopathy (ANE) with influenza A (H1N1) have been reported to date. The prognosis of ANE associated with H1N1 is variable; some cases resulted in severe neurologic complication, whereas other cases were fatal. Reports mostly focused on the diagnosis of ANE with H1N1 infection, rather than functional recovery. We report a case of ANE with H1N1 infection in a 4-year-old Korean girl who rapidly developed fever, seizure, and altered mentality, as well as had neurologic sequelae of ataxia, intentional tremor, strabismus, and dysarthria. Brain magnetic resonance imaging showed lesions in the bilateral thalami, pons, and left basal ganglia. To our knowledge, this is the first report of ANE caused by H1N1 infection and its long-term functional recovery in Korea.
Abstract
Several cases of acute necrotizing encephalopathy (ANE) with influenza A (H1N1) have been reported to date. The prognosis of ANE associated with H1N1 is variable; some cases resulted in severe neurologic complication, whereas other cases were fatal. Reports mostly focused on the diagnosis of ANE with H1N1 infection, rather than functional recovery. We report a case of ANE with H1N1 infection in a 4-year-old Korean girl who rapidly developed fever, seizure, and altered mentality, as well as had neurologic sequelae of ataxia, intentional tremor, strabismus, and dysarthria. Brain magnetic resonance imaging showed lesions in the bilateral thalami, pons, and left basal ganglia. To our knowledge, this is the first report of ANE caused by H1N1 infection and its long-term functional recovery in Korea.
참고문헌 (10)
- Lyon JB., "Acute necrotizing encephalopathy in a child with H1N1 influenza infection", Pediatr Radiol, 40, pp.200~205 (2010)
- Martin A., "Acute necrotizing encephalopathy progressing to brain death in a pediatric patient with novel influenza A (H1N1) infection", Clin Infect Dis, 50, pp.e50~e52 (2010)
- Mariotti P., "Acute necrotizing encephalopa thy during novel influenza A(H1N1)virus infection", Ann Neurol, 68, pp.111~114 (2010)
- 김란희, "2009-2011년에 발생한 신종 인플루엔자 A (H1N1)의 신경학적 양상", 대한소아신경학회지, 19(1), pp.54~60 (2011), 대한소아신경학회
- 최서영, "Novel Swine-Origin Influenza A (H1N1) Viral Encephalitis", Yonsei Medical Journal, 51(2), pp.291~292 (2010), 연세대학교의과대학
- Mizuguchi M., "Acute necrotising encephalopathy of childhood : a new syndrome presenting with multifocal, symmetric brain lesions", J Neurol Neurosurg Psychiatry, 58, pp.555~561 (1995)
- Mizuguchi M., "Acute necrotizing encephalopathy of childhood : a novel form of acute encephalopathy prevalent in Japan and Taiwan", Brain Dev, 19, pp.81~92 (1997)
- Trouillas P., "International cooperative ataxia rating scale for pharmacological assessment of the cerebellar syndrome : the Ataxia Neuropharmacology Committee of the World Federation of Neurology", J Neurol Sci, 145, pp.205~211 (1997)
- Schmitz-Hubsch T., "Scale for the assessment and rating of ataxia : development of a new clinical scale", Neurology, 66, pp.1717~1720 (2006)
- Okumura A., "Outcome of acute necrotizing encephalopathy in relation to treatment with corticosteroids and gammaglobulin", Brain Dev, 31, pp.221~227 (2009)