Neurologic and Neuromuscular Complications of Seasonal Influenza in Children
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Purpose: Influenza is generally known cause of acute respiratory disease. It is also cause of neurologic complications and has seldom non-benign nature. We report our cases of neurologic complications with influenza infection among children in 2013 seasonal endemic, and debate on benign nature of seasonal influenza. Methods: We retrospectively reviewed the medical records of all children who were confirmed influenza infection at the Konyang University Hospital, between December 2013 and March 2014. Results: A total of 279 children had influenza infections and 17 (6.1%) presented with neurologic complications. Eight patients manifested febrile seizures, one presented status epilepticus due to with aggravation of epilepsy, and seven presented with myositis. Influenza-associated encephalitis and optic neuritis were observed in each one patient. Most patients showed mild and benign progress, however the patient with influenza-associated encephalitis suffered severe complications. Conclusion: Children with seasonal influenza infections presented a wide spectrum of neurologic manifestations usually in young children. We recommend to suspect the possibility of influenza infection in the diagnosis of children manifesting neurologic symptoms during influenza epidemics.
Abstract
Purpose: Influenza is generally known cause of acute respiratory disease. It is also cause of neurologic complications and has seldom non-benign nature. We report our cases of neurologic complications with influenza infection among children in 2013 seasonal endemic, and debate on benign nature of seasonal influenza. Methods: We retrospectively reviewed the medical records of all children who were confirmed influenza infection at the Konyang University Hospital, between December 2013 and March 2014. Results: A total of 279 children had influenza infections and 17 (6.1%) presented with neurologic complications. Eight patients manifested febrile seizures, one presented status epilepticus due to with aggravation of epilepsy, and seven presented with myositis. Influenza-associated encephalitis and optic neuritis were observed in each one patient. Most patients showed mild and benign progress, however the patient with influenza-associated encephalitis suffered severe complications. Conclusion: Children with seasonal influenza infections presented a wide spectrum of neurologic manifestations usually in young children. We recommend to suspect the possibility of influenza infection in the diagnosis of children manifesting neurologic symptoms during influenza epidemics.
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