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Multiparameter Flow Cytometry: Advances in High Resolution Analysis

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초록

Over the past 40 years, flow cytometry has emerged as a leading, application-rich technology that supports high-resolution characterization of individual cells which function in complex cellular networks such as the immune system. This brief overview highlights advances in multiparameter flow cytometric technologies and reagent applications for characterization and functional analysis of cells modulating the immune network. These advances significantly support highthroughput and high-content analyses and enable an integrated understanding of the cellular and molecular interactions that underlie complex biological systems.

Abstract

Over the past 40 years, flow cytometry has emerged as a leading, application-rich technology that supports high-resolution characterization of individual cells which function in complex cellular networks such as the immune system. This brief overview highlights advances in multiparameter flow cytometric technologies and reagent applications for characterization and functional analysis of cells modulating the immune network. These advances significantly support highthroughput and high-content analyses and enable an integrated understanding of the cellular and molecular interactions that underlie complex biological systems.

참고문헌 (79)

  1. Shapiro, H. M., "Practical flow cytometry" (2003), Wiley-Liss
  2. Henel, G, "Basic theory and clinical applications of flow cytometry", Lab. Med, 38, pp.428~436 (2007)
  3. Hayashi, T., "Single-cell gene profiling of planarian stem cells using fluorescent activated cell sorting and its "index sorting" function for stem cell research", Dev. Growth. Differ, 52, pp.131~144 (2010)
  4. Doležel, J., "Chromosomes in the flow to simplify genome analysis", Funct. Integr. Genomics, 12, pp.397~416 (2012)
  5. Tighe, P., "Utility, reliability and reproducibility of immunoassay multiplex kits", Methods (2013)
  6. Ernst, D., "Bead-based flow cytometric assays: A multiplex assay platform with applications in diagnostic microbiology. In Advanced techniques in diagnostic microbiology", pp.427~443 (2006), Springer
  7. Morgan, E., "Cytometric bead array: a multiplexed assay platform with applications in various areas of biology", Clin. Immunol, 110, pp.252~266 (2004)
  8. Funato, Y., "Simultaneous measurement of six human cytokines using the Cytometric Bead Array System, a multiparameter immunoassay system for flow cytometry", Cytometry Res, 12, pp.93~97 (2002)
  9. Cook, E. B., "Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics", J. Immunol. Methods, 254, pp.109~118 (2001)
  10. Chattopadhyay, P. K., "Cytometry: today's technology and tomorrow's horizons", Methods, 57, pp.251~258 (2012)
  11. Herzenberg, L. A., "The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford", Clin. Chem, 48, pp.1819~1827 (2002)
  12. Zhang, P., "Combination of an aptamer probe to CD4 and antibodies for multicolored cell phenotyping", Am. J. Clin. Pathol, 134, pp.586~593 (2010)
  13. Telford, W. G., "Flow cytometry of fluorescent proteins", Methods, 57, pp.318~330 (2012)
  14. Robinson, J. P., "Computational analysis of high-throughput flow cytometry data", Expert. Opin. Drug Discov, 7, pp.679~693 (2012)
  15. De Rosa, S. C., "Beyond six colors: a new era in flow cytometry", Nat. Med, 9, pp.112~117 (2003)
  16. Appay, V., "Phenotype and function of human T lymphocyte subsets: consensus and issues", Cytometry A, 73, pp.975~983 (2008)
  17. Craig, F. E., "Flow cytometric immunophenotyping for hematologic neoplasms", Blood, 111, pp.3941~3967 (2008)
  18. Danna, E. A., "Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level", Curr. Opin. Chem. Biol, 10, pp.20~27 (2006)
  19. Krutzik, P. O., "High-content single-cell drug screening with phosphospecific flow cytometry", Nat. Chem. Biol, 4, pp.132~142 (2008)
  20. Maino, V. C., "Identification of functional subsets by flow cytometry: intracellular detection of cytokine expression", Cytometry, 34, pp.207~215 (1998)
  21. Perez, O. D., "Multiparameter analysis of intracellular phosphoepitopes in immunophenotyped cell populations by flow cytometry", Curr. Protoc. Cytom (2005)
  22. Chattopadhyay, P. K., "Brilliant violet fluorophores: a new class of ultrabright fluorescent compounds for immunofluorescence experiments", Cytometry A, 81, pp.456~466 (2012)
  23. Chattopadhyay, P. K., "Quantum dot technology in flow cytometry", Methods Cell Biol, 102, pp.463~477 (2011)
  24. Kalina, T., "EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols", Leukemia, 26, pp.1986~2010 (2012)
  25. Crissman, H. A., "Correlated measurements of DNA, RNA, and protein in individual cells by flow cytometry", Science, 228, pp.1321~1324 (1985)
  26. Peixoto, A., "Quantification of multiple gene expression in individual cells", Genome Res, 14, pp.1938~1947 (2004)
  27. Krutzik, P. O., "Fluorescent cell barcoding for multiplex flow cytometry", Curr. Protoc. Cytom (2011)
  28. Krutzik, P. O., "Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling", Nat. Methods, 3, pp.361~368 (2006)
  29. Bodenmiller, B., "Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators", Nat. Biotechnol, 30, pp.858~867 (2012)
  30. Nomura, L., "Standardization and optimization of multiparameter intracellular cytokine staining", Cytometry A, 73, pp.984~991 (2008)
  31. Suni, M. A., "Performance of plate-based cytokine flow cytometry with automated data analysis", BMC Immunol, 4, pp.9~ (2003)
  32. Gray, J. W., "Techniques in cell cycle analysis" (1987), Humana Press
  33. Darzynkiewicz, Z., "Lymphocyte stimulation: a rapid multiparameter analysis", Proc. Natl. Acad. Sci. U.S.A, 73, pp.2881~2884 (1976)
  34. Cappella, P., "A novel method based on click chemistry, which overcomes limitations of cell cycle analysis by classical determination of BrdU incorporation, allowing multiplex antibody staining", Cytometry A, 73, pp.626~636 (2008)
  35. Feig, C., "How apoptosis got the immune system in shape", Eur. J. Immunol, 37(Suppl 1), pp.S61~S70 (2007)
  36. Hanahan, D., "Hallmarks of cancer: the next generation", Cell, 144, pp.646~674 (2011)
  37. Wlodkowic, D., "Apoptosis and beyond: cytometry in studies of programmed cell death", Methods Cell Biol, 103, pp.55~98 (2011)
  38. Wlodkowic, D., "Cytometry in cell necrobiology revisited. Recent advances and new vistas", Cytometry A, 77, pp.591~606 (2010)
  39. Tanaka, T., "Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase", Cell Cycle, 6, pp.371~376 (2007)
  40. Schulz, K. R., "Single-cell phospho-protein analysis by flow cytometry", Curr. Protoc. Immunol (2012)
  41. Juan, G., "Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis", Cytometry, 32, pp.71~77 (1998)
  42. Fleisher, T. A., "Detection of intracellular phosphorylated STAT-1 by flow cytometry", Clin. Immunol, 90, pp.425~430 (1999)
  43. Chow, S., "Measurement of MAP kinase activation by flow cytometry using phospho- specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors", Cytometry, 46, pp.72~78 (2001)
  44. Zell, T., "Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo", Proc. Natl. Acad. Sci. U.S.A, 98, pp.10805~10810 (2001)
  45. Perez, O. D., "Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry", Nat. Biotechnol, 20, pp.155~162 (2002)
  46. Tazzari, P. L., "Flow cytometric detection of total and serine 473 phosphorylated Akt", J. Cell. Biochem, 86, pp.704~715 (2002)
  47. Krutzik, P. O., "Intracellular phospho- protein staining techniques for flow cytometry: monitoring single cell signaling events", Cytometry A, 55, pp.61~70 (2003)
  48. Chow, S., "Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations", Cytometry A, 67, pp.4~17 (2005)
  49. Suni, M. A., "Flow cytometric analysis of cell signaling proteins", Methods Mol. Biol, 717, pp.155~169 (2011)
  50. Irish, J. M., "Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells", Blood, 108, pp.3135~3142 (2006)
  51. Sadeghi, K., "Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling", J. Infect. Dis, 195, pp.296~302 (2007)
  52. Zeiser, R., "Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells", Blood, 111, pp.453~462 (2008)
  53. Perfetto, S. P., "Amine-reactive dyes for dead cell discrimination in fixed samples", Curr. Protoc. Cytom (2010)
  54. Henriksen, M., "Laser scanning cytometry and its applications: a pioneering technology in the field of quantitative imaging cytometry", Methods Cell Biol, 102, pp.161~205 (2011)
  55. Zuba-Surma, E. K., "Analytical capabilities of the ImageStream cytometer", Methods Cell Biol, 102, pp.207~230 (2011)
  56. Clutter, M. R., "Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry", Cytometry A, 77, pp.1020~1031 (2010)
  57. Krutzik, P. O., "Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples", Methods Mol. Biol, 699, pp.179~202 (2011)
  58. Kuckuck, F. W., "High throughput flow cytometry", Cytometry, 44, pp.83~90 (2001)
  59. Bashashati, A., "A survey of flow cytometry data analysis methods", Adv. Bioinformatics (2009)
  60. Lugli, E., "Data analysis in flow cytometry: the future just started", Cytometry A, 77, pp.705~713 (2010)
  61. Aghaeepour, N., "Rapid cell population identification in flow cytometry data", Cytometry A, 79, pp.6~13 (2011)
  62. Sachs, K., "Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes", Conf. Proc. IEEE Eng. Med. Biol. Soc, pp.6624~6627 (2009)
  63. Qiu, P., "Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE", Nat. Biotechnol, 29, pp.886~891 (2011)
  64. Pedreira, C. E., "Generation of flow cytometry data files with a potentially infinite number of dimensions", Cytometry A, 73, pp.834~846 (2008)
  65. Bagwell, C. B., "Breaking the dimensionality barrier", Methods Mol. Biol, 699, pp.31~51 (2011)
  66. Bendall, S. C., "Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum", Science, 332, pp.687~696 (2011)
  67. Ornatsky, O., "Highly multiparametric analysis by mass cytometry", J. Immunol. Methods, 361, pp.1~20 (2010)
  68. Auksorius, E., "Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications", Biomed. Opt. Express, 3, pp.661~666 (2012)
  69. Barteneva, N. S., "Imaging flow cytometry: coping with heterogeneity in biological systems", J. Histochem. Cytochem, 60, pp.723~733 (2012)
  70. Pierzchalski, A., "Introduction A: recent advances in cytometry instrumentation, probes, and methods--review", Methods Cell Biol, 102, pp.1~21 (2011)
  71. Shapiro, H. M, "Personal cytometers: slow flow or no flow?", Cytometry A, 69, pp.620~630 (2006)
  72. Petersen, T. W., "Flow cytometric characterization of marine microbes", Methods, 57, pp.350~358 (2012)
  73. Wlodkowic, D., "Wormometry-on-a-chip: Innovative technologies for in situ analysis of small multicellular organisms", Cytometry A, 79, pp.799~813 (2011)
  74. Orozco, A. F., "Flow cytometric analysis of circulating microparticles in plasma", Cytometry A, 77, pp.502~514 (2010)
  75. Chang, Q., "Emerging applications of flow cytometry in solid tumor biology", Methods, 57, pp.359~367 (2012)
  76. Tárnok, A., "Phenotypes of stem cells from diverse origin", Cytometry A, 77, pp.6~10 (2010)
  77. Ochatt, S. J, "Flow cytometry in plant breeding", Cytometry A, 73, pp.581~598 (2008)
  78. Petrunkina, A. M., "Cytometric solutions in veterinary andrology: Developments, advantages, and limitations", Cytometry A, 79, pp.338~348 (2011)
  79. Müller, S., "Functional single- cell analyses: flow cytometry and cell sorting of microbial populations and communities", FEMS Microbiol. Rev, 34, pp.554~587 (2010)

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