Sex-specific relationships between alcohol consumption and vitamin D levels: The Korea National Health and Nutrition Examination Survey 2009
0
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
This study assessed the association between vitamin D sufficiency (serum 25(OH)D ≥30 ng/mL) and alcohol consumption using data from the Korea National Health and Nutrition Examination Survey conducted in 2009. The following characteristics were obtained in 7,010 Korean participants ≥19-years-of-age: serum 25(OH)D level, alcohol consumption (drinking frequency, drinking number of alcoholic beverages on a typical occasion,average daily-alcohol intake), and potential confounders (age, residence, housing status, occupation, total fat and lean mass, smoking, physical activity,history of liver diseases, liver function, and daily intake of energy, protein, and calcium). After adjusting for confounders, vitamin D sufficiency in men was significantly associated with drinking frequency, number of alcoholic drinks consumed, and average daily alcohol intake; odds ratio of 1.21-1.72, 2.17-3.04, and 2.27-3.09, respectively. Increase in the three alcohol drinking-related behaviors was also linearly associated with increase in serum 25(OH)D level in men. By comparison, there was no significant association between alcohol intake and serum 25(OH)D level in women. The positive association between vitamin D sufficiency and alcohol consumption was evident only in Korean men.
Abstract
This study assessed the association between vitamin D sufficiency (serum 25(OH)D ≥30 ng/mL) and alcohol consumption using data from the Korea National Health and Nutrition Examination Survey conducted in 2009. The following characteristics were obtained in 7,010 Korean participants ≥19-years-of-age: serum 25(OH)D level, alcohol consumption (drinking frequency, drinking number of alcoholic beverages on a typical occasion,average daily-alcohol intake), and potential confounders (age, residence, housing status, occupation, total fat and lean mass, smoking, physical activity,history of liver diseases, liver function, and daily intake of energy, protein, and calcium). After adjusting for confounders, vitamin D sufficiency in men was significantly associated with drinking frequency, number of alcoholic drinks consumed, and average daily alcohol intake; odds ratio of 1.21-1.72, 2.17-3.04, and 2.27-3.09, respectively. Increase in the three alcohol drinking-related behaviors was also linearly associated with increase in serum 25(OH)D level in men. By comparison, there was no significant association between alcohol intake and serum 25(OH)D level in women. The positive association between vitamin D sufficiency and alcohol consumption was evident only in Korean men.
참고문헌 (14)
- Turner RT, "Skeletal response to alcohol", Alcohol Clin Exp Res, 24, pp.1693~1701 (2000)
- Laitinen K, "Deranged vitamin D metabolism but normal bone mineral density in Finnish noncirrhotic male alcoholics", Alcohol Clin Exp Res, 14, pp.551~556 (1990)
- Turner RT, "Chronic alcohol treatment results in disturbed vitamin D metabolism and skeletal abnormalities in rats", Alcohol Clin Exp Res, 12, pp.159~162 (1988)
- Gascon-Barré M, "Interrelationships between vitamin D3 and25-hydroxyvitamin D3 during chronic ethanol administration inthe rat", Metabolism, 31, pp.67~72 (1982)
- Jacques PF, "Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample", Am J Clin Nutr, 66, pp.929~936 (1997)
- Egan KM, "Vitamin D insufficiency among African-Americans in the southeastern United States: implications for cancer disparities (United States)", Cancer Causes Control, 19, pp.527~535 (2008)
- McCullough ML, "Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers", Am J Epidemiol, 172, pp.21~35 (2010)
- Choi HS, "Vitamin D insufficiency in Korea--a greater threat to younger generation: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008", J Clin Endocrinol Metab, 96, pp.643~651 (2011)
- Holick MF, "Vitamin D status: measurement, interpretation, and clinical application", Ann Epidemiol, 19, pp.73~78 (2009)
- Yoon YS, "Alcoholconsumption and the metabolic syndrome in Korean adults: the1998 Korean National Health and Nutrition Examination Survey", Am J Clin Nutr, 80, pp.217~224 (2004)
- Laitinen K, "Alcohol and bone", Calcif Tissue Int, 49(Suppl), pp.70~73 (1991)
- Sampson HW, "Alcohol, osteoporosis, and bone regulating hormones", Alcohol Clin Exp Res, 21, pp.400~403 (1997)
- Jugdaohsingh R, "Moderate alcohol consumption and increased bone mineral density: potential ethanol and non-ethanol mechanisms", Proc Nutr Soc, 65, pp.291~310 (2006)
- Millen AE, "Vitamin D assessment in populationbased studies: a review of the issues", Am J Clin Nutr, 87, pp.1102~1105 (2008)
