Association between nutrient intake and thyroid cancer risk in Korean women
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BACKGROUND/OBJECTIVES: The incidence of thyroid cancer has increased in many countries, including Korea. International differences in the incidence of thyroid cancer may indicate a role of diet, but findings from previous studies are inconclusive. Therefore, we aimed to investigate the roles of nutrients in thyroid cancer risk in Korean women. SUBJECTS/METHODS: We conducted a case-control study comprising 113 cases and 226 age-matched controls. Nutrient intake was assessed using a validated food frequency questionnaire, and the association between nutrient intake and thyroid cancer risk was estimated using a logistic regression model. RESULTS: We found that high calcium intake was associated with a reduced risk of thyroid cancer (OR [95% CI] = 0.55 [0.35-0.89]). Significant associations were observed among subjects who were older than 50 years, had low BMI, and had low calorie intake. However, other nutrients included in this study did not show any significant associations with thyroid cancer risk. CONCLUSION: This study suggested a possible protective effect of calcium on thyroid cancer risk. Well-designed prospective studies are required to confirm these findings.
Abstract
BACKGROUND/OBJECTIVES: The incidence of thyroid cancer has increased in many countries, including Korea. International differences in the incidence of thyroid cancer may indicate a role of diet, but findings from previous studies are inconclusive. Therefore, we aimed to investigate the roles of nutrients in thyroid cancer risk in Korean women. SUBJECTS/METHODS: We conducted a case-control study comprising 113 cases and 226 age-matched controls. Nutrient intake was assessed using a validated food frequency questionnaire, and the association between nutrient intake and thyroid cancer risk was estimated using a logistic regression model. RESULTS: We found that high calcium intake was associated with a reduced risk of thyroid cancer (OR [95% CI] = 0.55 [0.35-0.89]). Significant associations were observed among subjects who were older than 50 years, had low BMI, and had low calorie intake. However, other nutrients included in this study did not show any significant associations with thyroid cancer risk. CONCLUSION: This study suggested a possible protective effect of calcium on thyroid cancer risk. Well-designed prospective studies are required to confirm these findings.
참고문헌 (39)
- Pellegriti G, "Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors", J Cancer Epidemiol, 2013, pp.965212~ (2013)
- 정규원, "Prediction of Cancer Incidence and Mortality in Korea, 2015", Cancer Research and Treatment, 47(2), pp.142~148 (2015), 대한암학회[DOI]
- Verkooijen HM, "Diagnostic changes as a reason for the increase in papillary thyroid cancer incidence in Geneva, Switzerland", Cancer Causes Control, 14, pp.13~17 (2003)
- Dal Maso L, "Risk factors for thyroid cancer: an epidemiological review focused on nutritional factors", Cancer Causes Control, 20, pp.75~86 (2009)
- Harach HR, "Thyroid cancer, thyroiditis and dietary iodine: a review based on the Salta, Argentina model", Endocr Pathol, 19, pp.209~220 (2008)
- Horn-Ross PL, "Iodine and thyroid cancer risk among women in a multiethnic population: the Bay Area Thyroid Cancer Study", Cancer Epidemiol Biomarkers Prev, 10, pp.979~985 (2001)
- Blomberg M, "Thyroid cancer in Denmark 1943-2008, before and after iodine supplementation", Int J Cancer, 131, pp.2360~2366 (2012)
- Cléro É, "Dietary iodine and thyroid cancer risk in French Polynesia: a case-control study", Thyroid, 22, pp.422~429 (2012)
- Wingren G, "Determinants of papillary cancer of the thyroid", Am J Epidemiol, 138, pp.482~491 (1993)
- Jung SK, "The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case-control study in South Korea", Br J Nutr, 109, pp.118~128 (2013)
- Bosetti C, "A pooled analysis of case-control studies of thyroid cancer. VII. Cruciferous and other vegetables (International)", Cancer Causes Control, 13, pp.765~775 (2002)
- Truong T, "Role of dietary iodine and cruciferous vegetables in thyroid cancer: a countrywide case-control study in New Caledonia", Cancer Causes Control, 21, pp.1183~1192 (2010)
- Zhang LR, "Vitamin and mineral supplements and thyroid cancer: a systematic review", Eur J Cancer Prev, 22, pp.158~168 (2013)
- O'Grady TJ, "The association between selenium and other micronutrients and thyroid cancer incidence in the NIH-AARP Diet and Health Study", PLoS One, 9, pp.e110886~ (2014)
- Kim J., "Cancer screenee cohort study of the National Cancer Center in South Korea", Epidemiol Health, 36, pp.e2014013~ (2014)
- Ahn Y, "Validation and reproducibility of food frequency questionnaire for Korean genome epidemiologic study", Eur J Clin Nutr, 61, pp.1435~1441 (2007)
- Ahn Y, "Development of a semi-quantitative food frequency questionnaire based on dietary data from the Korea National Health and Nutrition Examination Survey", Nutr Sci, 6, pp.173~184 (2003)
- Willett WC., "Nutritional Epidemiology" (2013), Oxford University Press
- Han JM, "Obesity is a risk factor for thyroid cancer in a large, ultrasonographically screened population", Eur J Endocrinol, 168, pp.879~886 (2013)
- Cho YA, "Thyroid cancer risk and smoking status: a metaanalysis", Cancer Causes Control, 25, pp.1187~1195 (2014)
- Ron E, "A population-based case-control study of thyroid cancer", J Natl Cancer Inst, 79, pp.1~12 (1987)
- Park Y, "Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study", Arch Intern Med, 169, pp.391~401 (2009)
- Lipkin M., "Preclinical and early human studies of calcium and colon cancer prevention", Ann N Y Acad Sci, 889, pp.120~127 (1999)
- Lipkin M, "Effect of added dietary calcium on colonic epithelial-cell proliferation in subjects at high risk for familial colonic cancer", N Engl J Med, 313, pp.1381~1384 (1985)
- Lappe JM, "Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial", Am J Clin Nutr, 85, pp.1586~1591 (2007)
- Cho E, "Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies", J Natl Cancer Inst, 96, pp.1015~1022 (2004)
- Shin MH, "Intake of dairy products, calcium, and vitamin D and risk of breast cancer", J Natl Cancer Inst, 94, pp.1301~1311 (2002)
- D'Avanzo B, "Selected micronutrient intake and thyroid carcinoma risk", Cancer, 79, pp.2186~2192 (1997)
- Touvier M, "Dual Association of beta-carotene with risk of tobacco-related cancers in a cohort of French women", J Natl Cancer Inst, 97, pp.1338~1344 (2005)
- Berridge MJ, "Calcium signalling: dynamics, homeostasis and remodelling", Nat Rev Mol Cell Biol, 4, pp.517~529 (2003)
- Lamprecht SA, "Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms", Nat Rev Cancer, 3, pp.601~614 (2003)
- Jacobson EA, "Effects of dietary fat, calcium, and vitamin D on growth and mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene in female Sprague-Dawley rats", Cancer Res, 49, pp.6300~6303 (1989)
- Whitfield JF, "Calcium-cell cycle regulator, differentiator, killer, chemopreventor, and maybe, tumor promoter", J Cell Biochem Suppl, 22, pp.74~91 (1995)
- Sergeev IN., "Calcium as a mediator of 1,25-dihydroxyvitamin D3-induced apoptosis", J Steroid Biochem Mol Biol, 89-90, pp.419~425 (2004)
- Milner JA, "Molecular targets for nutrients involved with cancer prevention", Nutr Cancer, 41, pp.1~16 (2001)
- Xue L, "Influence of dietary calcium and vitamin D on diet-induced epithelial cell hyperproliferation in mice", J Natl Cancer Inst, 91, pp.176~181 (1999)
- Peterson E, "BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review", PLoS One, 7, pp.e29177~ (2012)
- Lee HJ, "Intakes of dairy products and calcium and obesity in Korean adults: Korean National Health and Nutrition Examination Surveys (KNHANES) 2007-2009", PLoS One, 9, pp.e99085~ (2014)
- Lee HJ, "Intakes of dairy products and calcium and obesity in Korean adults: Korean National Health and Nutrition Examination Surveys (KNHANES) 2007-2009", PLoS One, 9, pp.e99085~ (2014)