파킨슨병의 한약 치료에 대한 최신 임상연구 동향 고찰 - 2010년부터 2014년까지 중국 논문을 중심으로 -
Review of Current Clinical Studies for Herbal Medicine of Parkinson’s Disease in Traditional Chinese Medicine
2
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
The objective of this study was to review the current clinical studies about the effect of herbal medicine for Parkinson’s disease in China over the last 5 years and then to suggest the foundation for treatment and further studies. We had searched for studies in China National Knowledge Infrastructure(CNKI, http://www.cnki.net) and PubMed from January 2010 to December 2014. Key words were the various combinations of ‘帕金森’, ‘湯’, ‘丸’, ‘散’, ‘中醫藥’, 'Parkinson's disease', and 'herbal medicine'. Total 53 clinical studies were selected and analyzed. The most frequently used diagnostic criteria of Parkinson’s disease was the Unified Parkinson’s Disease Rating Scale(UPDRS). The most frequently used medical herb was Paeoniae Radix alba(白芍藥) more 30 times and the highest amount was Astragali radix(黃芪) 100g per day. The most frequent syndrome differentiation was liver kidney yin deficiency(肝腎陰虛). We found out there are many clinical studies of herbal medicine for Parkinson’s disease in China. These studies would be able to provide the basis of clinical research on Parkinson's disease, and also applied to the treatment of Parkinson’s disease in Korea.
Abstract
The objective of this study was to review the current clinical studies about the effect of herbal medicine for Parkinson’s disease in China over the last 5 years and then to suggest the foundation for treatment and further studies. We had searched for studies in China National Knowledge Infrastructure(CNKI, http://www.cnki.net) and PubMed from January 2010 to December 2014. Key words were the various combinations of ‘帕金森’, ‘湯’, ‘丸’, ‘散’, ‘中醫藥’, 'Parkinson's disease', and 'herbal medicine'. Total 53 clinical studies were selected and analyzed. The most frequently used diagnostic criteria of Parkinson’s disease was the Unified Parkinson’s Disease Rating Scale(UPDRS). The most frequently used medical herb was Paeoniae Radix alba(白芍藥) more 30 times and the highest amount was Astragali radix(黃芪) 100g per day. The most frequent syndrome differentiation was liver kidney yin deficiency(肝腎陰虛). We found out there are many clinical studies of herbal medicine for Parkinson’s disease in China. These studies would be able to provide the basis of clinical research on Parkinson's disease, and also applied to the treatment of Parkinson’s disease in Korea.
참고문헌 (77)
- Hoehn, M. M., "Yahr, Parkinsonism: onset, progress and mortality", Neurology, 17, pp.427~442 (1967)
- Barbeau, A., "Handbook of Neurology", pp.87~152 (1986), Elsevier
- De Lau, L. M., "Epidemiology of Parkinson’s disease", Lancet Neurol, 5(6), pp.525~535 (2006)
- "2002-2008 medical treatment trends analysis of geriatric diseases in Korea"[URL]
- Rice, J. E., "Thompson PD Movement disorders Ⅰ:parkinsonism and the akinetic-rigid syndromes", Med J Aust, 174(7), pp.357~363 (2001)
- 하지영, "특발성 파킨슨병 환자의 증상에 대한 침치료 효과", 대한한의학회지, 24(3), pp.602~613 (2003), 대한한의학회
- 박연철, "특발성 파킨슨 환자에서 經穴에 따른 鍼 치료 효과의 비교 연구", 대한침구의학회지, 24(4), pp.43~54 (2007), 대한침구의학회
- 박상민, "특발성 파킨슨병 환자에 대한 뜸치료가 UPDRS 및 심박변이도에 미치는 영향", 대한한의학회지, 26(2), pp.176~181 (2005), 대한한의학회
- Lee, M. S., "Effectiveness of acupuncture for Parkinson’s disease: A systemic review", Mov Disord, 23(11), pp.1505~1515 (2008)
- Lee, H. S,, "Scalp acupuncture for Parkinson's disease: a systematic review of randomized controlled trials", Chin J Integr Med, 19(4), pp.297~306 (2013)
- 김우경, "중국에서의 파킨슨병 두침치료 임상연구 논문분석", 동의신경정신과학회지, 22(4), pp.11~20 (2011), 대한한방신경정신과학회
- 김락형, "중국에서의 파킨슨병 침치료 임상연구 동향", Korean Journal of Acupuncture, 28(4), pp.147~158 (2011), 경락경혈학회
- Guoxin Zhang, "Effectiveness of Traditional Chinese Medicine as an Adjunct Therapy for Parkinson’s Disease: A Systematic Review and Meta-Analysis", PLOS ONE, 10(3), pp.e0118498~ (2015), Public Library of Science (PLoS)[DOI]
- Ru, D., "Qingxin Huatan Decoction 30 cases of Parkinson's disease", Shaanxi Journal of Traditional Chinese Medicine, 32(2), pp.163~164 (2011)
- Li, W., "Parkinson's disease 42 cases Modified Zhichan Treated", Shaanxi Journal of Traditional Chinese Medicine, 33(5), pp.549~551 (2012)
- Guo, D. J., "Treated ginseng spleen qi deficiency syndrome age-trembling observed 50 cases of non-motor symptoms", Zhejiang Journal of Traditional Chinese Medicine, 47(3), pp.175~176 (2012)
- Chen, X., "Clinical observation of Parkinson's disease TGD together Zhenganxifeng Treated", Xinjiang Journal of Traditional Chinese Medicine, 31(5), pp.13~16 (2013)
- Wen, X., "Effects of Chinese herbal medicine Pabing Ⅱ Formula on quality of life of patients with Parkinson’s disease at early-stage", China Journal of Traditional Chinese Medicine and Pharmacy, 28(10), pp.2917~2921 (2013)
- Guo, D., "Effect of Renshen Guipi Decoction on Emotional Disorder Caused by Parkinson Disease in the Aged with Syndrome of Qi and Blood Deficiency", Chinese Archives of Traditional Chinese Medicine, 31(3), pp.577~579 (2013)
- Huangzhi, L., "Observation of Nourishing Liver and Kidney, Nourishing Blood and Roujin on the Treatment of Liver and Kidney Yin Deficiency Type Parkinson’s Disease Syndrome", pp.2013
- Ye, H., "Effect of Nourishing Kidney and flattening tremor treatment of Parkinson's disease with depression and sleep disorders", Guangdong Medical Journal, 35(14), pp.2276~2278 (2014)
- Zhang, X., "Efficacy of Wenyang Zhuyu Tang combined definite madopar treatment for Vascular parkinsonism", Journal of New Chinese Medicine, 46(7), pp.47~48 (2014)
- Chen, M., "Clinical observation on Yiqi decoction for treatment of patients with Parkinson disease symptoms of constipation", Chinese Journal of Integrative Medicine on Cardio-, 2014, pp.12(1), 59~60
- Zhu, W., "30 Cases of Parkinson's Disease Treated by Huoxue Zhichan", Journal of Traditional Chinese Medicine, 51(8), pp.717~718 (2010)
- Zhu, W., "Clinical study of Parkinson's disease and kidney Decoction", Journal of Changchun University of Traditional Chinese Medicine, 26(4), pp.501~502 (2010)
- Liang, R., "Clinical evaluation of Ebony Pill Parkinson's Disease", pp.2010
- Zhou, F., "Clinical observation of modified "Zengye Chengqi Decoction" in treating 36 cases of constipation in Parkinson’s disease", Shanghai Journal of Traditional Chinese Medicine, 44(3), pp.46~47 (2010)
- Bai Q., "Effect of Nourishing Liver-kidney and Extinguishing Wind on the Symptoms of Parkinson’s Disease of Liver-kidney Yin Deficiency", Liaoning Journal of Traditional Chinese Medicine, 37(5), pp.846~848 (2010)
- Bai, Q., "Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases", Journal of Traditional Chinese Medicine, 51(2), pp.125~127 (2010)
- Chen, Y., "Xiaoyaosan treatment of Parkinson's disease with depression", Henan Traditional Chinese Medicine, 34(8), pp.1615~1616 (2014)
- Yang, M., "Powder improve depressive symptoms in patients with Parkinson's Evaluation", Guangming Journal of Chinese Medicine, 25(1), pp.31~32 (2010)
- Zhao, H., "Dingchan Efficacy Treated Liver-Kidney yin-deficiency symptoms of non-motor Parkinson's disease", Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 21(8), pp.562~564 (2011)
- Yu, C., "Study of Qufeng Wenshen Sanhan Decoction on 28 Patients with Parkinson's Disease", Hunan Journal of Traditional Chinese Medicine, 27(3), pp.1~2 (2011)
- Liu, Y., "Valuation about Curative Effect of Treating Parkinson’s Disease with Wumei Wan", pp.2011
- Hu, R., "24 Cases of Shaoyao Gancao Decoction for Treatment of Parkinson’s Disease with Secondary Dystonia", Journal of Sichuan of Traditional Chinese Medicine, 29(10), pp.78~79 (2011)
- Chen, Y., "Curative Observation on Treatment of 45 Cases with Non-motor Symptoms of Senile Tremor Syndrome in Blood Stasis Type by Xuefu Zhuyu Decoction", Strait Pharmaceutical Journal, 24(12), pp.216~212 (2012)
- Yu, Z., "Clinical Observation of Zhengan Xifeng decoction for Treating Parkinson’ Disease", Henan Traditional Chinese Medicine, 32(11), pp.1542~1543 (2012)
- Yang, Q., "Clinical Observation on Treating Parkinson’s Disease with the Shaoyao Gancao Decoction plus the Ganmai Dazao Decoction", Clinical Journal of Chinese Medicinie, 4(11), pp.1~2 (2012)
- Liu, Y., "Clinical Research of Treating Hypokinesia Type and Rigid Type Parkinson’s Disease with MaFuXin Decotion", pp.2012
- Guo, D., "Effect of Renshenguipi Decoction on Sleep Disorder Caused by Parkinson Disease in the Aged with Syndrome of Qi and Blood Deficiency", Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 22(2), pp.92~94 (2012)
- Jiayu, Q., "Clinical Observation on Treatment of 70 Cases with Parkinson’s Disease in Wind Phlegm and Blood Stasis Type by Xifeng Dingchan Pill", Chinese Journal of Traditional Medical Science and Technology, 19(3), pp.253~254 (2012)
- Ren, W., "Clinical Research on Treatment of the Vascular parkinson Syndrome by Bushen Huoxue Xifeng Fang", pp.2012
- Min, L., "Effects of Chinese herbal medicine Bushen Huoxue Granule on quality of life of patients with Parkinson disease: a randomized, double-blinded and placebo-controlled trial", Journal of Chinese Integrative Medicine, 10(3), pp.310~316 (2012)
- Zhang, D., "30 Cases of Parkinson’s Disease with Treatment Xifeng Zhizhen Decoction", Hunan Journal of Traditional Chinese Medicine, 29(6), pp.41~42 (2013)
- Ann, C., "Clinical Observation on Treatment of 30 Cases with Parkinson’s Disease by Bushen Huoxue Decoction", Guiding Journal of Traditional Chinese Medicine and Pharmacy, 19(6), pp.41~43 (2013)
- Zhang, X., "Clinical Research on the Treatment of Parkinson’s Disease with Strengthening Kidney and Activating Circulation", pp.2013
- Zhaotai, Q., "The Clinical Observation of Gu Ben Xi Feng Tang in Improving Autonomic Nervous Symptoms in Parkinson’s Disease", pp.2013
- Zhang, W., "Clinical observation of "Yangyin Xifeng Tongluo Decoction" in treating Parkinson’s disease of liver-kidney yin deficiency", Shanghai Journal of Traditional Chinese Medicine, 47(4), pp.36~37 (2013)
- Zheng, C., "Therapeutic effect evaluation of modified Wumei Pills on Parkinson’s disease", China Journal of Traditional Chinese Medicine and Pharmacy, 28(3), pp.857~859 (2013)
- Zhang, C., "The Study of Effects of Buyanghuanw Pill Jiajian Fang and Madopar on Parkinson’s Disease", pp.2013
- Liu, X., "Clinical Observation Xiaoyaosan treatment of Parkinson's disease with depression", Practical Geriatrics, 27(9), pp.778~780 (2013)
- Zhong, C., "To Observe Clinical Effect of Bushen Huoxue Tongluo Capsule on Patients with Parkinson’s Disease", pp.2013
- Li, M., "Effect of Bushen Huoxue Herbs on Depression of Patients with Parkinson's Disease", Journal of Chinese Medicinal Materials, 36(8), pp.1375~1378 (2013)
- Lin, S., "Analyzing the safety and efficacy of Turtle deer Dihuang Decoction in the treatment of Parkinson’s disease", Journal of China Prescription, 12(8), pp.10~11 (2014)
- Chen, S., "Clinical study of Parkinson disease treated with Bushen Huoxue Decoction", China Medical Herald, 11(22), pp.99~102 (2014)
- Zhou, J., "Random Control Study of Treating Parkinson’s Disease with Shudi Pingchan Decoction", Chinese Archives of Traditional Chinese, 32(6), pp.1395~1397 (2014)
- Wangya, J., "Effect of Wen yang chugeo jeong fa tang on the Yin deficiency fengdong vascular type of Parkinson’s Disease: A Report of 30 Cases", Journal of Sichuan of Traditional Chinese Medicine, 32(6), pp.108~109 (2014)
- Liling, L., "Clinical Observation of Nourishing Yin and Liver Decoction in Treating Non-motor Symptoms of Parkinsons Disease with Liver-kidney Deficiency Syndrome", pp.2014
- Sun, C., "The Clinical Curative Effect Observation for the Treatment of Parkinson’s Disease with the Method of Strengthening the Spleen and Reducing Phlegm and Claming Endogenous Wind", pp.2014
- Zhou, J., "Combination of “Shudi Pingchan Decoction” and “Zhenzhong Elixir” for the treatment of nonmotor symptoms of Parkinson’s Disease: a randomized controlled trial", Shanghai Journal of Traditional Chinese Medicine, 48(5), pp.38~44 (2014)
- Yuanqing, J., "Effect of yishentalganjieyuliaofa for Parkinson’s disease with depression", pp.2014
- Dong, H. l., "Clinical efficacy of modified Runchang pills in treatment of constipation among patients with qi-blood deficiency type Parkinson’s disease: a report of 30 cases", Hunan Journal of Traditional Chinese Medicine, 30(9), pp.17~19 (2014)
- Liling, L., "Clinical Observation of Nourishing Yin and Liver Decoction in Treating Non-motor Symptoms of Parkinsons Disease with Liver-kidney Deficiency Syndrome", pp.2014
- Xue, M., "Clinical Observation of Curative Effects of Guiling Pa’an Pill in the Treatment of Parkinson’s Disease(Deficiency of Kidney and Blood Stasis Type)", pp.2014
- Zhang, L., "The Clinical Intervention Research of Kangzhenzhijing Capsule for Pd Constipation of Blood Stasis Pneumatic", pp.2014
- Lv, S., "Clinical Study of Nourishing Blood and Rib Method for60Early Stage Parkinson of Stiffness and Less Dynamic Pattern", pp.2014
- 박병준, "특발성 파킨슨병·파킨슨증후군 환자 7례의 치료경과사례 고찰", 동의신경정신과학회지, 20(3), pp.283~295 (2009), 대한한방신경정신과학회
- 이은, "파킨슨병의 침구치료 동향에 대한 고찰", 대한한방내과학회지, 35(1), pp.12~23 (2014), 대한한방내과학회
- Tae-Hun Kim, "Herbal medicines for Parkinson's disease", 박사, Dept. of Oriental Internal Medicine, pp.2012
- Young-Ho Shim, "Herbal medicine treatment for drug induced parkinsonism", 석사, Dept. of Clinical Korean Medicine, pp.2013
- Fahn, S., "Recent Developments in Parkinson's Disease, Vol 2", Florham Park, NJ. Macmillan Health Care Information, 15, pp.3~163 (1987)
- Chaudhuri, K., "The Parkinson’s disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson’s disease", Journal of Neurolgy and Neurosurgery Psychiatry, 73, pp.629~635 (2002)
- Hamilton, M., "A rating scale for depression", J Neurol Neurosurg Psychiatry, 23(1), pp.56~ (1960)
- Webster, D. D., "Critical analysis of the disability in Parkinson’s disease", Modern Treatment, 5, pp.257~282 (1968)
- Sheng, H., "The Literature Research of Syndromes of TCM about Parkinson’s Disease", LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH, 22(4), pp.967~968 (2011)
- 김지영, "한국인 파킨슨 환자에서 비운동증상의 빈도와 특성과 대체의학 이용경험과의 관련성", 대한신경과학회지, 31(1), pp.8~14 (2013), 대한신경과학회
- Kim, S. R., "Use of complementary and alternative medicine by Korean patients with Parkinson’s disease", Clinical Neurology and Neurosurgery, 111, pp.156~160 (2009)
