침시술이 경피수분 손실량과 피부 수분함유량에 미치는 임상적 연구
Pilot Clinical Trial to Evaluate the Efficacy of Acupuncture Therapy on TEWL and Skin hydration
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The purpose of pilot clinical trial is to evaluate the efficacy and safety of acupuncture therapy on TEWL(Transepidermal Water Loss) and skin hydration. A total of 36 human who visited Dongshin University Oriental Medical Center from October 2nd, 2015 to July 31st, 2016 were included in the pilot clinical trial. Acupuncture therapy was performed at Gokji(LI11) and Daechu(GV14). We observed change of TEWL(Transepidermal Water Loss), skin hydration before and after acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically significant decline(8.01±2.55→6.58±1.97 g/h/m2, 7.40±2.65→4.99±1.89 g/h/m2). Index of skin hydration showed statistical significance(52.83±6.53→56.82±7.24, 63.50±8.57→64.96±8.48). To evaluate the safety, vital sign check were conducted and showed no statistically significant result. And there were no severe adverse events during this study. According to the above pilot clinical trial, it is suggested acupuncture therapy were effective for skin moisturizing.
Abstract
The purpose of pilot clinical trial is to evaluate the efficacy and safety of acupuncture therapy on TEWL(Transepidermal Water Loss) and skin hydration. A total of 36 human who visited Dongshin University Oriental Medical Center from October 2nd, 2015 to July 31st, 2016 were included in the pilot clinical trial. Acupuncture therapy was performed at Gokji(LI11) and Daechu(GV14). We observed change of TEWL(Transepidermal Water Loss), skin hydration before and after acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically significant decline(8.01±2.55→6.58±1.97 g/h/m2, 7.40±2.65→4.99±1.89 g/h/m2). Index of skin hydration showed statistical significance(52.83±6.53→56.82±7.24, 63.50±8.57→64.96±8.48). To evaluate the safety, vital sign check were conducted and showed no statistically significant result. And there were no severe adverse events during this study. According to the above pilot clinical trial, it is suggested acupuncture therapy were effective for skin moisturizing.
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