급성염증 동물모델에서 軟玉粉과 軟玉水의 염증억제 효과
In Vivo Studies on Anti-inflammatory Activity of Nephrite
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Abstract
Most inflammatory disorders are usually treated using anti-inflammatory drugs including non-steroidal anti-inflammatory drugs (NSAID) and steroidal anti-inflammatory drugs (SAID). In a prolonged use, however, they may frequently produce adverse side-effects. Thus, it is necessarily required to develop a new anti-inflammatory drug with little side-effects. Nephrite has been widely used by traditional oriental medicine to cure the various chronic diseases. In order to verify the anti-inflammatory activity of nephrite, the TPA (12-O-tetradecanoylphorbol -acetate) or the croton oil-induced edema was developed in the mouse ears and the nephrite powder suspension or the nephrite water was directly applied to the ear edema. It was found that nephrite could significantly reduce the ear swelling implying its strong potential as an active anti-inflammatory agent when comparing to indomethacin, a non-steroidal anti-inflammatory drug.
참고문헌 (19)
- 이승헌, "Skin barrier", pp.1~7 (2004), 여문각
- 대한광업진흥공사, "광업진흥 1993년 신년호" (1993), 서울
- Choi, "A study on the Characteristics of Ok using Chuncheon Nephriye", 9, pp.65~74 (2000)
- Mauda Palmer Die Verborgene, "KRAFT der KRISTALLE und der EDELSTEINE"
- "Analgesic and topical anti-inflammatory activity of Hypericum canariense L", 96(3), pp.591~596 (2005)
- Maltese, "Synthesis and anti-inflammatory activity of natural and semisynthetic geranyloxycoumarins", 14(9), pp.2241~2243 (2004)
- Kim, "Anti-inflammatory activity of Sedum kamtschaticum", 90(2-3), pp.409~414 (2004)
- Michel, "Topical antiinflammatory effects of the ether extract from Protium kleinii and -amyrin pentacyclic triterpene", 507(1-3), pp.253~259 (2005)
- Yokota, "Exacerbated and prolonged allergic and non-allergic inflammatory cutaneous reaction in mice with targeted interleukin-18 expression in the skin", 121(3), pp.502~509 (2003)
- Park, "Antiinflammatory activity of Synurus deltoides", 18(11), pp.930~933 (2004)
- 허준, "對譯 東醫寶鑑" (1999), 법인문화사
- 이시진, "國譯 本草綱目" (1992), 일중사
- Yeom, "In vitro inhibition of pro-inflammatory mediator mRNA expression by nephrite in lipopolysaccharide-induced mouse macrophage cells", 18(6), pp.1622~1627 (2005)
- Choi, "Effects of jade water and jade powder on the sterilization by ultraviolet ray Journal of national sciences 20", 20, pp.82~89 (2001)
- Kim, "Anti-inflammatory and related pharmacological activities of the n-BuOH subfraction of mushroom Phellinus linteus", 93(1), pp.141~146 (2004)
- Cunha, "A cascade of cytokines mediates mechanical inflammatory hypernociception in mice", 102(5), pp.1755~1760 (2005)
- Marie, "In vivo anti-inflammatory activity of Alchornea cordifolia", 92(2-3), pp.209~214 (2004)
- Romay, "Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation", 47(8), pp.334~338 (1998)
- A, "Effects of valeryl salicylate on models of acute inflammation in mice", 48(5), pp.437~443 (2003)