中風환자의 濕痰변증과 혈중지질의 상관성에 관한 Case-Control 연구
Case-Control Study on Relationship of Dampness-phlegm to Blood Lipid Level in Stroke Patients
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The purpose of this study was to investigate the relationship of Dampness-phlegm to blood lipid level and second reason of hyperlipidemia in acute stroke patients by case-control study. This study was done over 348 patients hospitalized in the Oriental Medical Hospital of Daejeon University of November 2006 to July 2008. Patients had been interviewed by residents and medical specialists who studied standard operation procedures in Fundamental Study for Syndrome of Oriental Medicine for Stroke. Study subjects consisted of 86 patients who distributed to Dampness-phlegm by medical specialist and discriminating program as the caseⅠ group, 157 patients who distributed to Dampness-phlegm by medical specialist or discriminating program as the caseⅡ group and 191 patients who distributed to Non-Dampness-phlegm by medical specialist and discriminating program as the control group. For the purpose of obtaining suitable result we analyzed blood lipid level of each group by univariate and multivariate logistic analysis. Dampness-phlegm was not significant correlated with increasing of Total cholesterol, Triglyceride and decreasing of HDL cholesterol. Dampness-phlegm was significant correlated with increasing LDL cholesterol and the independent predictors of hyperlipoproteinemia by multivariate logistic analysis. Dampness-phlegm was not significant correlated with diabetes melitus, liver disease, kidney disease, obesity and abdominal obesity. In this study, we demonstrated new relationship between Dampness-phlegm and LDL cholesterol. Based on these results, it is suggested that Dampness-phlegm would be the independent predictors of hyperlipoproteinemia. And more prospective studies are to be done with more clinical data.
Abstract
The purpose of this study was to investigate the relationship of Dampness-phlegm to blood lipid level and second reason of hyperlipidemia in acute stroke patients by case-control study. This study was done over 348 patients hospitalized in the Oriental Medical Hospital of Daejeon University of November 2006 to July 2008. Patients had been interviewed by residents and medical specialists who studied standard operation procedures in Fundamental Study for Syndrome of Oriental Medicine for Stroke. Study subjects consisted of 86 patients who distributed to Dampness-phlegm by medical specialist and discriminating program as the caseⅠ group, 157 patients who distributed to Dampness-phlegm by medical specialist or discriminating program as the caseⅡ group and 191 patients who distributed to Non-Dampness-phlegm by medical specialist and discriminating program as the control group. For the purpose of obtaining suitable result we analyzed blood lipid level of each group by univariate and multivariate logistic analysis. Dampness-phlegm was not significant correlated with increasing of Total cholesterol, Triglyceride and decreasing of HDL cholesterol. Dampness-phlegm was significant correlated with increasing LDL cholesterol and the independent predictors of hyperlipoproteinemia by multivariate logistic analysis. Dampness-phlegm was not significant correlated with diabetes melitus, liver disease, kidney disease, obesity and abdominal obesity. In this study, we demonstrated new relationship between Dampness-phlegm and LDL cholesterol. Based on these results, it is suggested that Dampness-phlegm would be the independent predictors of hyperlipoproteinemia. And more prospective studies are to be done with more clinical data.
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