급성기 중풍환자에서 비만 및 혈액지표의 기허 및 화열 변증의 차이에 대한 고찰
Study on the Obesity and Blood parameters Differences between Fire/Heat and Qi-deficiency Pattern Identification/Syndrome Differentiation among Acute Stroke Patients
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Object : In the present study, we investigated the obesity and blood parameters between Qi-definency and Fire/Heat pattern identification/syndrome differentiation (PI/SD) in acute stroke patients. Materials and Methods : A total of 391 stroke patients within 7 days after onset were consecutively recruited from 12 hospitals across South Korea during Nov. 1st, 2006 to Jun. 31th, 2009. They were diagnosed as Fire/Heat or Qi-deficiency among five PI/SD subtypes by two independent stroke experts. We investigated the differences of obesity and blood characteristics between Fire/Heat and Qi-deficiency by statistical analyses. Results : In male subjects, obesity was significantly associated with Fire/Heat PI/SD. The averaged mean of BMI(24.13kg/㎡) and waist circumference(89.34cm) of Fire/Heat group were higher than those of Qi-deficiency group(22.60kg/㎡ and 83.43 cm, respectively). The number of obese patients was larger in the Fire/Heat group than Qi-deficiency group (p=0.001). Hyperlipidemia was also related with Fire/Heat. However, obesity was not associated with PI/SD in female subjects and the number of hyperlipidemic patients was higher in Qi-deficiency group. Among blood parameters, the levels of triglyceride and fasting blood sugar were higher in the Fire/Heat group compared with the Qi-deficiency group in male subjects. However, total cholesterol of Qi-deficiency was higher than Fire/Heat group in female subjects. Conclusion : In this study, we study showed that obesity and hyperlipidemia are significantly difference between Qi-deficiency and Fire/Heat. We suggest that PI/SD may be associated with clinical characteristics and large population study between PI/SD and clinical characteristics including blood parameters are needed.
Abstract
Object : In the present study, we investigated the obesity and blood parameters between Qi-definency and Fire/Heat pattern identification/syndrome differentiation (PI/SD) in acute stroke patients. Materials and Methods : A total of 391 stroke patients within 7 days after onset were consecutively recruited from 12 hospitals across South Korea during Nov. 1st, 2006 to Jun. 31th, 2009. They were diagnosed as Fire/Heat or Qi-deficiency among five PI/SD subtypes by two independent stroke experts. We investigated the differences of obesity and blood characteristics between Fire/Heat and Qi-deficiency by statistical analyses. Results : In male subjects, obesity was significantly associated with Fire/Heat PI/SD. The averaged mean of BMI(24.13kg/㎡) and waist circumference(89.34cm) of Fire/Heat group were higher than those of Qi-deficiency group(22.60kg/㎡ and 83.43 cm, respectively). The number of obese patients was larger in the Fire/Heat group than Qi-deficiency group (p=0.001). Hyperlipidemia was also related with Fire/Heat. However, obesity was not associated with PI/SD in female subjects and the number of hyperlipidemic patients was higher in Qi-deficiency group. Among blood parameters, the levels of triglyceride and fasting blood sugar were higher in the Fire/Heat group compared with the Qi-deficiency group in male subjects. However, total cholesterol of Qi-deficiency was higher than Fire/Heat group in female subjects. Conclusion : In this study, we study showed that obesity and hyperlipidemia are significantly difference between Qi-deficiency and Fire/Heat. We suggest that PI/SD may be associated with clinical characteristics and large population study between PI/SD and clinical characteristics including blood parameters are needed.
참고문헌 (21)
- 통계청, "2004 사망원인 통계연보" (2004)
- 국민건강보험공단, "2002~2007년도 노인성 질환자 진료 추이 분석" (2008)
- 국민건강보험공단, "2006 건강보험통계연보" (2007)
- 강효신, "中風臨床資料에 대한 統計的 分析方法硏究", 대한한의학회지, 17, pp.302~328 (1996)
- 노진환, "중풍변증진단기준안에 대한 임상적 연구" (2001), 경희대학교 대학원
- Lin S, "Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis", Jie He Za Zhi, 18, pp.392~395 (1998)
- Lin ZX, "Relation between malondialdehyde generation by platelets and plasma thromboxane B2 and diagnostic classification by syndrome differentiation of traditional Chinese medicine in stroke during acute stage", Zhong Xi Yi Jie He Za Zhi, 11, pp.714~716 (1991)
- Chen P, "Review of the relation between polymorphism of genes and TCM syndrome differentiation", Zhongguo Zhong Xi Yi Jie He Za Zhi, 23, pp.852~854 (2003)
- Zhu MZ, "Study on correlationship of TCM syndrome type and expression of ICAM-1, CD62P in patients with ischemic stroke", Zhongguo Zhong Xi Yi Jie He Za Zhi, 25, pp.225~227 (2005)
- Zhao R, "Relationship between lipometabolic disorder in stroke with TCM syndrome differentiation and typing", Zhongguo Zhong Xi Yi Jie He Za Zhi, 18, pp.339~341 (1998)
- 전국한의과대학 심계내과학교실, "心系內科學", pp.331~342 (2006), 군자출판사
- 고성규, "뇌혈관질환의 한양방적인 위험요인 규명 및 진단 표준화 연구를 위한 CRF 및 SOP 개발", 대한한의학회지, 27(1), pp.204~219 (2006), 대한한의학회
- 하유군, "급성기 뇌중풍환자의 비만 및 복부비만과의 임상적 제특징 분석", 대한한방내과학회지, 29(1), pp.149~159 (2008), 대한한방내과학회
- 이혜상, "안동주변 농촌지역 50세 이상 주민의 신체계측치 및 생화학적 영양상태에 관한 연구 (2)", 한국식품영양과학회지, 37(12), pp.1599~1608 (2008), 한국식품영양과학회
- Lepor NE, "National Cholesterol Education Program Adult Treatment Panel III. Summary of the third report of the National Cholesterol Education Program Adult Treatment Panel III", Rev Cardiovasc Med, 2(3), pp.160~165 (2001)
- 고정민, "고령화사회의 도래에 따른 기회와 위협" (2002), 삼성경제연구소
- 문승희, "한국형 중풍 변증 표준안-Ⅱ의 변증별 변증지표의 분포 및 타당도에 관한 연구", 동의생리병리학회지, 22(2), pp.487~496 (2008), 대한동의병리학회
- 진승희, "女性 肥滿의 誘發類型別 일반 증상과 검사 특성 硏究", 대한한의학회지, 25(1), pp.172~187 (2004), 대한한의학회
- Song YM, "Body mass index and ischemic and hemorrhagic stroke: a prospective study in Korean men", Stroke, 35, pp.831~836 (2004)
- Park JW, "BMI and stroke risk in Korean women", Obesity, 16, pp.396~401 (2008)
- 趙洪健, "肥滿의 槪念 및 辨證施治에 關한 文獻的 考察", 대전대학교 한의학연구소 논문집, 7, pp.533~541 (1998)