Primary Gastric Small Cell Carcinoma: A Case Identified as a large Subepithelial Tumor from Invisible State in 6 months
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Primary gastric small cell carcinoma (GSCC) is one of the gastroenteropancreatic neuroendocrine tumors. It is a rare cancer with avery aggressive behavior and a poor prognosis because of the high rate of metastases. It is usually found in far advanced stage. Weexperienced a case of GSCC which had developed into a large subepithelial tumor (SET) from invisible state in a short period. A65-year-old man consulted our hospital because of early gastric cancer. He underwent endoscopic submucosal dissection for the earlygastric cancer at high body posterior wall. After 6 months, the follow-up endoscopy showed a large newly developed SET-like lesionwith central ulceration at the gastric cardia. Endoscopic biopsy revealed GSCC. Total gastrectomy was performed. One out of the 26perigastric lymph nodes had a metastasis. He received 6 cycles of adjuvant chemotherapy with etoposide and cisplatin. He is still ingood health 12 months after operation.
Abstract
Primary gastric small cell carcinoma (GSCC) is one of the gastroenteropancreatic neuroendocrine tumors. It is a rare cancer with avery aggressive behavior and a poor prognosis because of the high rate of metastases. It is usually found in far advanced stage. Weexperienced a case of GSCC which had developed into a large subepithelial tumor (SET) from invisible state in a short period. A65-year-old man consulted our hospital because of early gastric cancer. He underwent endoscopic submucosal dissection for the earlygastric cancer at high body posterior wall. After 6 months, the follow-up endoscopy showed a large newly developed SET-like lesionwith central ulceration at the gastric cardia. Endoscopic biopsy revealed GSCC. Total gastrectomy was performed. One out of the 26perigastric lymph nodes had a metastasis. He received 6 cycles of adjuvant chemotherapy with etoposide and cisplatin. He is still ingood health 12 months after operation.
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