Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background/Aims: Sclerotherapy with aluminum potassium sulfate and tannic acid (ALTA) has a potent effect on internalhemorrhoids. In this retrospective study, we compared the effects of endoscopic ALTA therapy and standard ALTA therapy. Methods: We investigated patients who underwent treatment for internal hemorrhoids at our institution between 2014 and 2016. Theywere divided into a standard ALTA group (n=33, treated using proctoscopy) and an endoscopic ALTA group (n=48). We compared theclinical findings between the 2 groups. Results: There were no intergroup differences in background factors. The mean ALTA dose was 21.9±7.2 mL and 17.8±3.4 mL inthe standard and endoscopic ALTA groups, respectively (p<0.01). Adverse events occurred in 4 patients (12.1%) from the standardALTA group and 6 patients (12.5%) from the endoscopic ALTA group. In both groups, the patients reported good satisfaction withthe therapeutic effect at 1 month after the procedure. Hemorrhoids recurred in 2 patients (6.3%) from the standard ALTA group and 4patients (8.3%) from the endoscopic ALTA group. Conclusions: Endoscopic ALTA sclerotherapy is equivalent to standard ALTA therapy in terms of efficacy, adverse events, andrecurrence. Therefore, it is a useful non-surgical option for patients with internal hemorrhoids who prefer a less invasive treatment.
Abstract
Background/Aims: Sclerotherapy with aluminum potassium sulfate and tannic acid (ALTA) has a potent effect on internalhemorrhoids. In this retrospective study, we compared the effects of endoscopic ALTA therapy and standard ALTA therapy. Methods: We investigated patients who underwent treatment for internal hemorrhoids at our institution between 2014 and 2016. Theywere divided into a standard ALTA group (n=33, treated using proctoscopy) and an endoscopic ALTA group (n=48). We compared theclinical findings between the 2 groups. Results: There were no intergroup differences in background factors. The mean ALTA dose was 21.9±7.2 mL and 17.8±3.4 mL inthe standard and endoscopic ALTA groups, respectively (p<0.01). Adverse events occurred in 4 patients (12.1%) from the standardALTA group and 6 patients (12.5%) from the endoscopic ALTA group. In both groups, the patients reported good satisfaction withthe therapeutic effect at 1 month after the procedure. Hemorrhoids recurred in 2 patients (6.3%) from the standard ALTA group and 4patients (8.3%) from the endoscopic ALTA group. Conclusions: Endoscopic ALTA sclerotherapy is equivalent to standard ALTA therapy in terms of efficacy, adverse events, andrecurrence. Therefore, it is a useful non-surgical option for patients with internal hemorrhoids who prefer a less invasive treatment.
참고문헌 (17)
- Hachiro Y, "Aluminum potassium sulfate and tannic acid(ALTA)injection as the mainstay of treatment for internal hemorrhoids", Surg Today, 41, pp.806~809 (2011)
- Miyamoto H, "ALTA injection sclerosing therapy : non-excisional treatment of internal hemorrhoids", Hepatogastroenterology, 59, pp.77~80 (2012)
- Tokunaga Y, "Impact of less invasive treatments including sclerotherapy with a new agent and hemorrhoidopexy for prolapsing internal hemorrhoids", Int Surg, 98, pp.210~213 (2013)
- Miyamoto H, "Aluminum potassium sulfate and tannic acid sclerotherapy for Goligher Grades II and III hemorrhoids : results from a multicenter study", World J Hepatol, 8, pp.844~849 (2016)
- Davis BR, "The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the management of hemorrhoids", Dis Colon Rectum, 61, pp.284~292 (2018)
- Brown SR, "Haemorrhoids: an update on management", Ther Adv Chronic Dis, 8, pp.141~147 (2017)
- Takaaki Yano, "Comparison of Injection Sclerotherapy Between 5% Phenol in Almond Oil and Aluminum Potassium Sulfate and Tannic Acid for Grade 3 Hemorrhoids", Annals of Coloproctolgy, 31(3), pp.103~105 (2015), 대한대장항문학회
- 임석원, "Aluminum Potassium Sulfate and Tannic Acid Injection for Hemorrhoids", Annals of Coloproctolgy, 28(2), pp.73~77 (2012), 대한대장항문학회[DOI]
- Tomiki Y, "Endoscopic sclerotherapy with aluminum potassium sulfate and tannic acid for internal hemorrhoids", Endoscopy, 46(Suppl 1 UCTN), pp.E114~ (2014)
- Tomiki Y, "Treatment of internal hemorrhoids by endoscopic sclerotherapy with aluminum potassium sulfate and tannic acid", Diagn Ther Endosc, 2015, pp.517690~ (2015)
- Yano T, "Outcomes of case-matched injection sclerotherapy with a new agent for hemorrhoids in patients treated with or without blood thinners", Surg Today, 43, pp.854~858 (2013)
- ASGE Technology Committee, "Devices for the endoscopic treatment of hemorrhoids", Gastrointest Endosc, 79, pp.8~14 (2014)
- Zhang T, "Cap-assisted endoscopic sclerotherapy for hemorrhoids : methods, feasibility and efficacy", World J Gastrointest Endosc, 7, pp.1334~1340 (2015)
- Tomiki Y, "Evaluation of endoscopic hemorrhoidal ligation in 119 patients", Dig Endosc, 15, pp.30~34 (2003)
- Abe T, "Distal hemorrhoidectomy with ALTA injection : a new method for hemorrhoid surgery", Int Surg, 99, pp.295~298 (2014)
- Albuquerque A, "Rubber band ligation of hemorrhoids: a guide for complications", World J Gastrointest Surg, 8, pp.614~620 (2016)
- Yano T, "Prospective study comparing the new sclerotherapy and hemorrhoidectomy in terms of therapeutic outcomes at 4 years after the treatment", Surg Today, 44, pp.449~453 (2014)
