Is Submucosal Injection Helpful in Cold Snare Polypectomy for Small Colorectal Polyps?
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Background/Aims: Cold snare polypectomy (CSP) is an effective method of polyp removal for small colorectal polyps. However,the effect of submucosal injection in cold snare endoscopic mucosal resection (CS-EMR) for small polyps is unclear. Therefore, thisstudy aimed to evaluate the effect of submucosal injection in CS-EMR for small polyps. Methods: Between 2018 and 2019, 100 consecutive small colorectal polyps (5–10 mm) were identified in 58 patients. The first50 consecutive polyps were removed by CS-EMR, and the remaining 50 were removed by CSP. Demographic data, clinical data,endoscopic findings, procedure times, complication rates, and pathology data were collected. Results: No difference in the complete resection rate was observed between the CS-EMR and CSP groups. A total of 9 polyps showedpost-polypectomy bleeding (7 had immediate bleeding, 1 had delayed bleeding, and 1 had both immediate and delayed bleeding). No difference in the bleeding rate was observed between the two groups. In multivariate analysis, warfarin (odds ratio [OR], 42.334;95% confidence interval [CI], 1.006–1,781.758) and direct-acting oral anticoagulants (OR, 35.244; 95% CI, 3.853–322.397) showed asignificantly increased risk of bleeding. Conclusions: The effect of submucosal injection in CSP was not significant for small colorectal polyps.
Abstract
Background/Aims: Cold snare polypectomy (CSP) is an effective method of polyp removal for small colorectal polyps. However,the effect of submucosal injection in cold snare endoscopic mucosal resection (CS-EMR) for small polyps is unclear. Therefore, thisstudy aimed to evaluate the effect of submucosal injection in CS-EMR for small polyps. Methods: Between 2018 and 2019, 100 consecutive small colorectal polyps (5–10 mm) were identified in 58 patients. The first50 consecutive polyps were removed by CS-EMR, and the remaining 50 were removed by CSP. Demographic data, clinical data,endoscopic findings, procedure times, complication rates, and pathology data were collected. Results: No difference in the complete resection rate was observed between the CS-EMR and CSP groups. A total of 9 polyps showedpost-polypectomy bleeding (7 had immediate bleeding, 1 had delayed bleeding, and 1 had both immediate and delayed bleeding). No difference in the bleeding rate was observed between the two groups. In multivariate analysis, warfarin (odds ratio [OR], 42.334;95% confidence interval [CI], 1.006–1,781.758) and direct-acting oral anticoagulants (OR, 35.244; 95% CI, 3.853–322.397) showed asignificantly increased risk of bleeding. Conclusions: The effect of submucosal injection in CSP was not significant for small colorectal polyps.
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