점막하 종양 형태의 위 림프상피종양 암종(Gastric Lymphoepithelioma-like Carcinoma) 1예
A Case of Gastric Lymphoepithelioma-like Carcinoma Presenting as a Submucosal Tumor
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림프상피종양 암종(lymphoepithelioma-like carcinoma, LELC)은 식도, 위, 담관, 타액 선, 폐, 자궁, 피부 등에서 발생한다. 위 LELC는 전체 위암의 1～4%를 차지하며 림프구성 간질을 가지며, 비교적 좋은 예후와 높은 Epstein-Barr 바이러스와의 연관성으로 주목을 받고 있다. 최근 저자들은 49세 여자 환자로 미란을 동반한 점막하 종양이 있어 시행한 내시경하 조직 생검에서 MALT 림프종이 의심되었으나, 위 아전 절제술 후 조직검사에서 위 LELC로 확진된 점막하 종양 형태의 조기위암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Lymphoepithelioma-like carcinoma (LELC) occurs in esophagus, stomach, bile duct, salivary gland, lung, uterus, skin, and so on. The incidence of gastric LELC is 1∼4 percents of all stomach cancers. Gastric LELC has a lymphoid stroma and shows a good prognosis and high association with Epstein-Barr virus. We experienced a case of patient with gastric LELC. The patient was 49- year-old woman. and the endoscopic finding showed a submucosal tumor with central erosion. The histologic findings of endoscopic biopsies were suggestive of low grade MALT lymphoma. but the histologic findings of the surgical specimen were consistent with gastric LELC. We report a case of gastric LELC presenting as a submucosal tumor, with a brief review of the literature.
참고문헌 (14)
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